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Doctor insights on: Panhematopenia Splenic Primary

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Upper Abdomen (Definition)

Draw a transverse line through the umbilicus and the upper abdomen includes every part of the belly above this line and below the ...Read more


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Define differential diagnosis of prolymphocytic leukemia or mantle cell leukemia.

Define differential diagnosis of prolymphocytic leukemia or mantle cell leukemia.

They are too differe: There should be no confusion between these two entities. One is a lymphoma(nodal disease) the other one is a blood cancer that should not affect the lymph nodes. Rather easy diagnosis if you are seeing the right type of specialist! ...Read more

Dr. Liawaty Ho Dr. Ho
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What causes an inhomogenous spleen in hodgkin lymphoma?

Dr. Liawaty Ho Dr. Ho
1 doctor agreed:
What causes an inhomogenous spleen in hodgkin lymphoma?

Spleen involvement: Spleen involvement from hodgkin's lymphoma can give you heterogeneous/inhomogenous appearance of the spleen in the ct scan. A pet scan will tell you whether this is involvement from hodgkin's lymphoma or rather from other causes. ...Read more

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Why is igm elevated in primary biliary cirrhosis (cholangitis)?

Why is igm elevated in primary biliary cirrhosis (cholangitis)?

Immune dysregulation: The immune system is not functioning normally in primary biliary cirrhosis. That and the chronic inflammation contrive to raise IgM. ...Read more

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What causes an inhomogeneous spleen in hodgkin lymphoma?

What causes an inhomogeneous spleen in hodgkin lymphoma?

Lymphoma vs. other: The spleen in hl may be heterogeneous/inhomogeneous/non-uniform due to lymphoma involvement, spleen infarction (death) due to cancer death in the spleen, or infection, or "other". The radiologist may or may not be able to determine that and your oncologist might be able to say more about it with knowing the clinical history. ...Read more

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What causes an enlarged liver in a sickle cell anemia patients?

What causes an enlarged liver in a sickle cell anemia patients?

The bad cells: In simplest terms, the sickle ("bad") cells need to be removed because they get "trapped" in the liver where they are disposed of. These cells don't live as long as normal red blood cells, so the liver is working over time. ...Read more

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What's the difference between primary biliary cirrhosis and primary sclerosing cholangitis?

Similar symptoms: Distinct diseases that announce themselves in the same way. Both destroy the small bile ducts within the liver and produce jaundice, itching and sometimes failure of the liver. The microscopic picture, labs, and treatment options are as strikingly different as the presentations are similar. ...Read more

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Pediatrics. IGM0.43 WBC4.1 RBC3.60 PLATELETS120 MCV107.0 MCH34.5 NEUTROPHIL0.66 MONOCYTE0.04 BRUISING EASY does this indicate MDS or APLASTIC AMENIA?

Pediatrics. IGM0.43 WBC4.1 RBC3.60 PLATELETS120 MCV107.0 MCH34.5 NEUTROPHIL0.66 MONOCYTE0.04 BRUISING EASY does this indicate MDS or APLASTIC AMENIA?

Easy bruise: These results do not point to an aplastic condition because there is normal WBC count and adequate platelets. They should have done labs for bleeding diathesis such as Prothrombin time(PT/INR) and Partial thromboplastin time (PTT) as well as possible blood clotting factor levels. ...Read more

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Is primary biliary cirrhosis hereditary?

Is primary biliary cirrhosis hereditary?

Basically no: There's a pair of genes that carry the ability to develop the disease and these run in families, but it's not inherited like sickle cell, huntington's or some of the other familiar entities. http://www.medicalnewstoday.com/releases/151640.php. ...Read more

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Please explain: 5 CM irregular splenic lesion. Differential diagnosis lymphoma and splenic metastasis. Could this be cancer?

Please explain: 5 CM irregular splenic lesion. Differential diagnosis lymphoma and splenic metastasis. Could this be cancer?

Yes: Both are forms of cancer. It could also be a benign hemangioma, an epidermoid cyst, an infart (how's your overall vascular health?) or any of a number of other entities. What to do next will depend on your history and physical exam. You're in no immediate danger but this very much needs to be followed up. Many of the lymphomas especially are very curable with today's biotech. ...Read more

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What causes a splenic infarction?

What causes a splenic infarction?

No Blood to Spleen: A splenic infarction occurs when there is not enough blood going to the spleen to give it nutrients & oxygen its cells need to survive. Anything that cuts off blood supply to the spleen can cause an infarct. Ex. Trauma causing blood vessels to be destroyed, sickle cell anemia & other problems that lead to clogged arteries going to the spleen, autoimmune disease, blood cell disease, emboli, etc. ...Read more

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Please describe the mortality rate for acute lymphocytic leukemia?

Please describe the mortality rate for acute lymphocytic leukemia?

Differs depending...: On the subtype of all, age and risk stratification. Pts with b-cell phenotypes tend to do better than those with t-cell dz. Children tend to do better than adolescents and adults. There are also several molecular abnormalities with prognostic significance. Not enough room here to list. Taking all comers, survival among adults is 40-50% while for children, 80-85%. Ask if you need more specifics. ...Read more

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Is primary sclerosing cholangitis rare?

Is primary sclerosing cholangitis rare?

Yes: The goal of managing acute attacks is antibiotics and IV fluids. In about 15%, emergency decompression or surgery is needed. Prevention of future attacks of cholangitis is based on removing biliary stones and debris, dilation or resection of strictures, and establishing optimal biliary drainage. Also important to rule out the clonorchis parasite. Your GI doctor can discuss newest treatments. ...Read more

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What does splenic lesion mean and how dangerous is it?

What does splenic lesion mean and how dangerous is it?

Not enough info: What kind of lesion do you mean? A mass? An infarct? A vascular lesion? You need to provide specifics. ...Read more