Doctor insights on:
Panhematopenia Splenic Primary
Can a splenic hemangioma cause splenic swelling? Would a tumor on your spleen cause splenic swelling?
Possible: If either one is large enough it can. ...Read more
No: Liver hemangiomas occur at random and are harmless. ...Read more
Lymphoma vs. other: The spleen in hl may be heterogeneous/inhomogeneous/non-uniform due to lymphoma involvement, spleen infarction (death) due to cancer death in the spleen, or infection, or "other". The radiologist may or may not be able to determine that and your oncologist might be able to say more about it with knowing the clinical history. ...Read moreSee 1 more doctor answer
Right renal cell carcinoma extensive retroperitoneal lymphadenopathy IVC & renal vein infiltration. Can you tell stage or prognosis from this report?
Poor: This is high stage disease with a poor prognosis. ...Read more
The bad cells: In simplest terms, the sickle ("bad") cells need to be removed because they get "trapped" in the liver where they are disposed of. These cells don't live as long as normal red blood cells, so the liver is working over time. ...Read more
Similar symptoms: Distinct diseases that announce themselves in the same way. Both destroy the small bile ducts within the liver and produce jaundice, itching and sometimes failure of the liver. The microscopic picture, labs, and treatment options are as strikingly different as the presentations are similar. ...Read more
Pediatrics. IGM0.43 WBC4.1 RBC3.60 PLATELETS120 MCV107.0 MCH34.5 NEUTROPHIL0.66 MONOCYTE0.04 BRUISING EASY does this indicate MDS or APLASTIC AMENIA?
Easy bruise: These results do not point to an aplastic condition because there is normal WBC count and adequate platelets. They should have done labs for bleeding diathesis such as Prothrombin time(PT/INR) and Partial thromboplastin time (PTT) as well as possible blood clotting factor levels. ...Read moreSee 4 more doctor answers
Immunodeficiency, enlarged spleen, enlarged liver, anemia of chronic disease, are these serious issues?
You bet: And I hope are you under the care of an immunologist and hematologist. ...Read more
Basically no: There's a pair of genes that carry the ability to develop the disease and these run in families, but it's not inherited like sickle cell, huntington's or some of the other familiar entities. http://www.medicalnewstoday.com/releases/151640.php. ...Read more
Please explain: 5 CM irregular splenic lesion. Differential diagnosis lymphoma and splenic metastasis. Could this be cancer?
Yes: Both are forms of cancer. It could also be a benign hemangioma, an epidermoid cyst, an infart (how's your overall vascular health?) or any of a number of other entities. What to do next will depend on your history and physical exam. You're in no immediate danger but this very much needs to be followed up. Many of the lymphomas especially are very curable with today's biotech. ...Read more
Is there a possible link between hereditary hemochromatosis, polycythemia vera (primary jak2 mutation), & idiopathic pulmonary arterial hypertension?
No Blood to Spleen: A splenic infarction occurs when there is not enough blood going to the spleen to give it nutrients & oxygen its cells need to survive. Anything that cuts off blood supply to the spleen can cause an infarct. Ex. Trauma causing blood vessels to be destroyed, sickle cell anemia & other problems that lead to clogged arteries going to the spleen, autoimmune disease, blood cell disease, emboli, etc. ...Read moreSee 2 more doctor answers
Differs depending...: On the subtype of all, age and risk stratification. Pts with b-cell phenotypes tend to do better than those with t-cell dz. Children tend to do better than adolescents and adults. There are also several molecular abnormalities with prognostic significance. Not enough room here to list. Taking all comers, survival among adults is 40-50% while for children, 80-85%. Ask if you need more specifics. ...Read moreSee 1 more doctor answer
Yes: The goal of managing acute attacks is antibiotics and IV fluids. In about 15%, emergency decompression or surgery is needed. Prevention of future attacks of cholangitis is based on removing biliary stones and debris, dilation or resection of strictures, and establishing optimal biliary drainage. Also important to rule out the clonorchis parasite. Your GI doctor can discuss newest treatments. ...Read more
Not enough info: What kind of lesion do you mean? A mass? An infarct? A vascular lesion? You need to provide specifics. ...Read more