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Doctor insights on: Pancytopenia Chemotherapy Aplastic Anemia

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Is pancytopenia resulting from chemotherapy is same as aplastic anemia?

Is pancytopenia resulting from chemotherapy is same as aplastic anemia?

No: Aplastic anemia means something is wrong with your bone marrow and it cannot make red blood cells, white blood cells or platelets. It can be caused by toxins, infections, or autoimmune problems. Often the cause is never found. Pancytopenia from chemotherapy means a decrease in red blood cells, white blood cells and platelets caused by the toxic effect of chemo. This improves with time. ...Read more

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Dr. Scott Keith
38 doctors shared insights

Pancytopenia (Definition)

This is a decrease in all the cell lines of your blood. Meaning the white count, hemoglobin and platelets. If someone is anemic, the hemoglobin is low. If someone us thrombocytopenic, the platelet count is low. If someone is pancytopenic, all cell lines are ...Read more


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How is pancytopenia developed during aplastic anemia?

How is pancytopenia developed during aplastic anemia?

Production stops: The body continuously recycles & replaces different cells in the blood. Red cells last ~100days, platelets several hours, other cells vary. The healthy system acheives a steady state of producing cells as fast as they break down. If an event such as a toxic exposure (chloramphenacol) or tumor invasion shuts down the "factory", no new material will be made & you get low on everything. ...Read more

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Do they give chemotherapy for aplastic anemia?

Do they give chemotherapy for aplastic anemia?

For BMT...: Chemotherapy is given to ablate the bone marrow when you treat aplastic anemia with a bone marrow transplant. Otherwise, immunosuppressive medications are the standard of care for treatment. ...Read more

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What medications treat aplastic anemia?

What medications treat aplastic anemia?

Many: Immune suppression with drugs like steroids, cyclosporine, and anti-thymocyte globulin (horse). Bone marrow transplantation is another important type of treatment for aplastic anemia in young people. ...Read more

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What are the signs you get with aplastic anemia?

BM failure: Aplastic anemia is caused by bone marrow failure to produce all blood cells ( affecting white cell, red blood cells as well as platelet). It can be presented with pallor, fatigue/tired, lack of energy, shortness of breath on exertion, episodes of infections, bleeding episodes, increased abdominal girth due to enlargement of spleen, etc. ...Read more

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What're the signs and symptoms of aplastic anemia?

Aplastic anemia: Usually present with significant fatigue, anemia, shortness of breath on activity, dizziness, multiple episodes of infections which could be life threatening, easy bruising, bleeding from low platelet. Discuss more in detail with your doctor. ...Read more

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Can Lamotrigine cause aplastic anemia?

Can Lamotrigine cause aplastic anemia?

Unfortunately, yes: Unfortunately, the very good drug for epilepsy and to some extent mood disorders, Lamotrigine can cause aplastic anemia in a very rare number of individuals. AA is present worldwide at a rate of about 4 cases per 1 million (word wide). 3.2 cases per million would be ACQUIRED such as from exposure to medication or other reasons. Usually found in younger individuals on the drug. ...Read more

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Can aplastic anemia cause infertility?

Yes: Any severe illness can have a negative impact on fertility. In this specific case the therapies can also haver an impact on long term reproductive issues. ...Read more

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Should someone with aplastic anemia take multivitamins?

Multivitamins: My answer is 'yes, ' but i also believe that every adult should take a multivitamin a day, and older adults should add calcium (1000 mg/d) and vitamin d (at least 800 iu/d). For aplastic anemia, make sure you get enough folate (ie. A prenatal vitamin or a separate supplement) and vitamin b12. Some of the drugs used to treat aplastic anemia may interfere with some vitamins, so you may need more. ...Read more

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Can long untreated pernicious anemia give you the same symptoms of aplastic anemia with out actually having it. ?

PA: Is due to deficiency of B12 and/or folate (folic acid). Anemia is anemia, whatever the cause. If due to folate (folic acid) deficiency B12 must also be given or you will wind up with a nasty compliocation. ...Read more

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I have moderate aplastic anemia i really want to have a baby but i'm not sure if its safe or not. What are the risks and what do you think I should do?

Probably safe: You need to discuss with your doctor. Is your aa in remission? Are you requiring transfusions? What about any other health problems? Lots of unknowns. My understanding is that transfusion requirements might go up during pregnancy but most of the time it is safe if you are well compensated when you get pregnant. ...Read more

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Can aplastic anemia be cured?

Can aplastic anemia be cured?

Possible: Aplastic anemia can be treated with immunosuppressive medications with resolution in a significant percentage of patients. Younger patients can be successfully treated with donor bone marrow transplants. ...Read more

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Can neglis aplastic anemia be cured?

What is neglis?: Regarding aplastic anemia, yes there are good treatments for it. Standard of care for a young person with severe aplastic anemia and a matched sibling donor is an hematopoietic stem cell transplant. For those without a suitable donor, immune suppression is standard of care. If you can clarify the word "neglis" for us, we are happy to provide additional info. Cheers. ...Read more

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What are the tests for aplastic anemia?

What are the tests for aplastic anemia?

Many: The most basic is the cbc, which will give you hemoglobin, hematocrit, white cell count, and platelet counts. An additional important test is a reticulocyte count which gives you the production index of red cells. Your doctor can advise you further, based on your symptoms and history. Hope this helps. ...Read more

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What sort of problem is aplastic anemia?

What sort of problem is aplastic anemia?

Aplastic anemia: Aplastic anemia is a serious problem of the blood sytem and bone marrow. The problem is that the bone marrow, where new blood cells are normally made, stops producing new cells, so you end up with low red blood cell counts, low white blood cell counts, and low platelet counts. The causes may be nutritional, cancer-related, toxin-related (eg, certain drugs), or genetic. See a hematologist. ...Read more

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What are the symptoms of aplastic anemia?

Aplastic anemia: Aplastic anemia can make all of the blood cells low. Low red cells causes anemia. The symptoms of anemia can be fatigue, dizziness, pallor, chest pain, and shortness of breath. Low white cells make the patient susceptible to fever and a variety of infections. Low platelets make one likely to have bruising, bleeding, or petechiae (small purple freckles on the skin). ...Read more

Dr. Devon Webster
963 doctors shared insights

Chemotherapy (Definition)

The term chemotherapy typically is used to describe using chemicals to treat ...Read more


Dr. Steven Ginsberg
1,276 doctors shared insights

Anemia (Definition)

Any condition where there is a decrease in the red blood ...Read more