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Doctor insights on: Pancuronium

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Dr. Martin Sokoll
32 doctors shared insights

Pancuronium (Overview)

Pancuronium is a neuromuscular blocker which is a kind of anesthetic agent.


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Will Narcan (naloxone) reverse opiate overdose after cardiac arrest has occurred?

Will Narcan (naloxone) reverse opiate overdose after cardiac arrest has occurred?

Probably not: Narcan (naloxone) will reverse respiratory arrest. This means that if a person has stopped breathing due to an overdose of Oxycontin or heroin, for example, Narcan (naloxone) can bring back the drive to breathe. If the person doesn't breathe for a long time, though, the heart will stop, which is called cardiac arrest, due to lack of oxygen. Narcan (naloxone) won't fix that. This is why narcotic abuse is so dangerous. ...Read more

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Dr. Martin Sokoll
32 doctors shared insights

Pancuronium (Overview)

Pancuronium is a neuromuscular blocker which is a kind of anesthetic agent.


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What effect does pancuronium have on your nervous system?

What effect does pancuronium have on your nervous system?

Relaxes muscles: It is an injectable skeletal muscle relaxer. It should be used only by an anesthesia provider as it causes prolonged paralysis of muscles and will stop ones breathing. ...Read more

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Will Narcan (naloxone) reverse an opiate overdose once cardiac arrest has occurred?

Will Narcan (naloxone) reverse an opiate overdose once cardiac arrest has occurred?

Not completely: Narcan (naloxone) can reverse a narcotic overdose to a point. If someone takes a narcotic overdose, and it is enough to stop breathing, the lack of oxygen and rise in carbon dioxide can cause the heart to stop ( cardiac arrest) at that point simply reversing the effect of the narcotic that started the process is not enough, one take additional measures to restore a pulse and resuscitate the patient. ...Read more

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Will Narcan (naloxone) still reverse opiate overdose once cardiac arrest has occurred?

Will Narcan (naloxone) still reverse opiate overdose once cardiac arrest has occurred?

Unclear: Usually breathing stops with opiate overdose and then cardiac arrest occurs. Reversing with Narcan (naloxone) may allow breathing to restart, but the cardiac arrest would still have to be treated with CPR and usual measures. Depending on the duration of cardiac arrest attempts may or may not be successful, thus the uncertainty. ...Read more

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Why is chlordiazepoxides, diazepam, clofibrate, barbiturates contraindicated in renal failure?

Why is chlordiazepoxides, diazepam, clofibrate, barbiturates contraindicated in renal failure?

Impaired elimination: All drugs that are taken are eventually metabolized and eliminated from the body. Although liver enzymes perform the bulk of metabolizing of these agents, elimination of the drug and their metabolites relies, to varying degrees, on the kidney. If the kidneys are failing, elimination is impaired, and a toxic buildup of the drug and/or its metabolites is possible. ...Read more

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Can nalbuphine (nubain) be used intrathecally?

Can  nalbuphine (nubain) be used intrathecally?

No: Only three drugs are fda approved for intrathecal administration: morphine, Baclofen and ziconotide. Other medications are used by physician discretion. Nalbuphine has not being used at all. ...Read more

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Is propofol dangerous?

Is propofol dangerous?

No, if......: All medications can be dangerous if used inappropriately. However, if used correctly and within accepted guidelines, medications, including propofol, are considered safe and effective. Propofol should only be used by anesthesiologists who have been properly trained on its use. ...Read more

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Can administration of Narcan (naloxone) in a cardiac arrest victim be helpful?

Can administration of Narcan (naloxone) in a cardiac arrest victim be helpful?

In opiate overdose: But that is often late in the game, as your brain is much more sensitive than your heart to the lack of oxygen, and the arrest is likely to go poorly. ...Read more

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Why drug addicts used barbiturates?

Why drug addicts used barbiturates?

Course of addiction : Typically drug addicts use drugs because of the way it makes them feel. Drugs of abuse are fast acting, hit the reward center of the brain and are thus reinforcing. As tolerance for the drug's effects develop, people take more of the drug in hope of obtaining the same high feeling. Physical dependence occurs and the drug is taken no longer to get high but to try to feel normal & avoid withdrawal. ...Read more

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What is flumazenil (clonazepam) detox?

What is flumazenil (clonazepam) detox?

Risky detox tool: Flumazanil is currently not recommended to treat chronic benzodiazepines by the American College of Medical Toxicology. There is a very real risk that rapid reversal of benzodiazepines can lead to refractory seizures only treatable with barbiturates as flumazanil binds to GABA receptors with greater affinity, which could lead to unopposed glutamate stimulation. Benzodiazepine tapers are better ...Read more

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Can narcan (naloxone) cause seizures?

Can narcan (naloxone) cause seizures?

Potentially, yes: A seizure would be very dose dependent and would be unusual, but possible based on the preceding medications on board at time of usage. Other variables contributing would include level of blood electrolytes, serum glucose, history of recreational drug use, alcohol ingestion or sudden cessation, and prior head injury. ...Read more

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Is morphine used to quicken death?

Is morphine used to quicken death?

Not for humans: Active euthanasia is illegal in most jurisdictions. However, morphine may be administered for terminal sedation or to provide comfort to someone in respiratory distress during the dying process. This is considered ethical even though it may make death come somewhat sooner. ...Read more

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Why do we do gastric lavage in intravenous opium poisoning?

Why do we do gastric lavage in intravenous opium poisoning?

Beats Me!: Intravenous Narcan (naloxone) works great without the mess and avoids the possibilty of pulmonary aspiration. ...Read more

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When is atracurium used?

When is atracurium used?

Renal failure/insuff: Atracurium is a muscle relaxant which is not dependent on kidney for elimination. So we use it for patients with poor kidney function or failure. ...Read more

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Can i.M. Administration of Narcan (naloxone) in a cardiac arrest victim be helpful?

IM not so much: Narcan (naloxone) can reverse respiratory depression caused by opiate overdose, but if that has lead to a respiratory arrest causing cardiac arrest, the IV form would be much more useful, and only useful then when circulated by chest compressions. ...Read more

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When is inapsine (droperidol) used?

When is inapsine (droperidol) used?

Refractory PONV: Inapsine (droperidol) is also known as Droperidol which was extensively used in 90s then it had fda warning for qt prolongation leading to cardiac arrest so we have not been using it unless patients have resistant postoperative nausea and vomiting. ...Read more

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Dr. Alan Ali Dr. Ali
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How is gastric lavage done?

Dr. Alan Ali Dr. Ali
2 doctors agreed:
How is gastric lavage done?

Gastric lavage: A flexible tube is inserted through the nose, down the throat & into the stomach, the contents o the stomach are suctioned out through the tube, and the stomach is then rinsed with saline solution or sterile water. ...Read more

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Is benzodiazepine abuse curable?

Benzodiazepine treat: It is well established that addictions are associated with other conditions such as mood and anxiety disorder. In an well done study in arch gen psychiatry. 2008;65(1):47-52 they found in comparison with major depression, bipolar ii disorder was associated with the development of alcohol and benzodiazepine use and disorders. If you treat correctly the mood disorder you improve treating addict. ...Read more

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Dr. Heidi Fowler
5 doctors shared insights

Pavulon (Definition)

Pavulon is a neuromuscular blocker which is a ...Read more