Doctor insights on:
Pancreatic Triacylglycerol Lipase
Are pancreatic enzymes (amylase and lipase) always elevated if pancreatic cancer is present?? What about insulin blood level?
Insulin levels /P.Ca: Serum amylase and/or lipase levels: Elevated in less than 50% of patients with resectable pancreatic cancers and in only 25% of patients with unresectable tumors. Tumor markers such as CA 19-9 antigen and CEA: 75-85% have elevated CA 19-9 levels; 40-45% have elevated CEA levels.The odds of getting pancreatic cancer were worse for men with type 2 diabetes and the highest insulin levels. ...Read moreSee 1 more doctor answer
Lipases, such as lipoprotein lipase and endothelial lipase, are enzymes that breakdown circulating triglycerides (tg). Specifically, lipases degrade tg rich lipoproteins including chylomicrons, very low density lipoprotein (vldl) and remnant particles produced by breakdown of chylomicron and vldl particles. Decreased lipase function leads to accumulation of ...Read more
I have elevated liver enzyme ast(sgot)412 ALT (sgpt) 317 GGT 186 dilation of the common bile duct 1 CM no gallbladder?
Liver issue: Enzymes ast and alt are inside liver cells. When liver is injured by disease or medication, enzymes leak out, resulting in elevation. Can be due to many reasons, including medications like statins. An elevated GGT suggest biliary problems, but is not that specific. The normal common bile duct measures less than 0.8 cm, but after the gb is removed, can be 1cm. Complete history needed for this. ...Read moreSee 1 more doctor answer
Which test is better for diagnosing pancreas insufficiency: stool panc elastase or serum lipase/amylase? Would either diagnose pancreatic cancer?
Both together: Neither of the tests alone tells much. A combination of tests and exams will lead to diagnosis. Pancreatic cancer is not able to be ruled out by any test or imaging study. It can only be absolutely proven by some form of biopsy. A ct guided needle or egd with brushing a may be the only way to find it. ...Read more
History & physical: If the pancreas is inflamed or damaged, amylase and lipase are often up, and it's not subtle. If your pancreas isn't functioning properly, you'll be losing weight with no explanation and probably have diarrhea / steatorrhea. Your physician can check your stool for pancreatic enzymes. It's rare but with a suggestive history, a screen may show something that could respond to enzyme replacement. ...Read more
NOT VERY!!!: Hi. Pancreatic polypeptide (PP) is NOT a screening test for pancreatic tumors. The only pancreatic cells that make PP are rare neuroendocrine cells in the Islets of Langerhans (an already tiny fraction of the pancreas). And those would be a TINY, TINY fraction of all pancreatic tumors. But hey, if it's a PP secreting neuroendocrine tumor of the pancreas, you'd have it dialed! Good luck! ...Read moreSee 1 more doctor answer
Don't treat labs: Omega-3's have been a massive disappointment in most areas when subjected to scientific testing. Most important is finding WHY these liver tests are up. If it's chronic hepatitis B or C, hemochromatosis, Wilson's, or autoimmune hepatitis, you're going to die if you're not diagnosed & Rx'd. If this is non-alcoholic steatohepatitis, nothing will help as much as getting aerobically fit. ...Read more
They may: It is not unusual for patients to have slight elevations in their liver enzymes with gall stones. This is probably caused by sub clinical inflammation in the gall bladder. Significant elevations are seen in acute cholecystitis and elevation of the bilirubin can be due due common duct stones with obstruction. ...Read more
Lfts worsening-serum gammagt level 647u/l, serum alk phosphate 654u/l.Othr blood/heps normal.Mri &scans done. 3polyps large14mm in gallbladder-remove?
See specialist: The elevation in ggtp and alkaline phosphatase in the setting of gallbladder polyps that large mandates that you see a liver specialist before embarking on surgery. There are two types of specialists you should see, a hepatologist, a liver internal medicine doctor to make sure this is not some type of hepatitis or liver disease and then a liver surgeon to decide if the polyp is cancerous. Do asap. ...Read moreSee 1 more doctor answer
Pancreatic cancer?I had a pancreatic protocol ct/hida/liver, pancreas, CBC blood test/stool test/colonoscopy.All perfect.I still have light/yellow stool
Stop worrying: You have nothing to worry about except that fact that you are still a smoker, which i hope you'll stop. If everybody with light-colored stools consumed health-care dollars searching for pancreatic cancer, it'd be a huge waste. Evidently you're not even jaundiced. Please stop reading internet scare stuff, look for another cause of your abdominal pain ; stop reading internet scare stuff. ...Read more
7mm periampullary lesion, 3 liver lesions, total beta hCG is high, anion gap-10, monocytes-1.1, chloride high, erc low, cbd & pancreatic duct dilation?
Your question?: I appreciate your sharing this, but no one here will be able to make the call. Unless your HCG is extremely high, it means nothing. The other labs are not helpful. Your periampullary lesion has hopefully been biopsied, as will your liver lesions if the radiologist cannot certify them as benign. Hoping celiac sprue has been ruled in or out, along with whipple's and common lactose intolerance. ...Read more
Normal pancreatic enzymes, normal liver enzymes, normal CBC, normal ESR & C-RP. does this rule out pancreatic and liver cancer?
Why do you ask?: Why would you think you have this stuff at age 20? You've written about this before. You owe it to yourself and those who love you to get with someone who can help you out these thoughts out of your mind and get on with studying, getting job skills and experience, perhaps finding romance and meaningful things to enjoy. To be brave, act brave. You're anything but helpless. ...Read more
Lab:ldl:159, cholesterol:267, triglycerides:347, hdl:39, chol/hdl:6.8, tsh:9.79, free t4:0.80, testosterone:total:78/free:3.1, eosinophil:7.1.Recommendation?
Talk to your doc!: Your cholesterol & triglycerides are too high. Proper nutrition could help fix this. Your HDL is too low. Physical activity would raise this. Your TSH is too high so you may want to consider levothyroxine. Your total & free t are more difficult to interpret b/c you gave results w/o reference ranges. As i've noted before, there are many ways to check/measure testosterone so reference range is key. ...Read more
Are normal cbc, billuprin, amylase and lipase levels, CT scan and qualitative fecal fat test a good indication against pancreatic cancer?
On ursodeoxycholic acid, transaminases chronically fluctuating elevated ALT 50-200 AST 40-80.ALP 90-107. MRCP normal,fibroscan normal,what could it be?
Difficult question: Why the ursodiol? If for blood cholesterol, there may be better options (I don't see CF or PBC on your history). Sounds like you're getting a work up for the elevated enzymes. Consider a virtual consult with GI specialist for a thorough review of lab and imaging results. ...Read more
Idiopathic recurring pancreatitis, no alcoholism, gallstones, pain, high triglycerides. Only elevated amylase and lipase. What is next step?
See your doctor soon: It is wise to see your doctor soon regarding this. Depending on how high your amylase and lipase are it could be acute or chronic pancreatitis, and considering that you're on medications and have a history of acute pancreatitis, it's even more important to see your doctor. Diet restrictions like low fat intake and fluid replacement and monitoring are needed to be done, so see dr. Asap. ...Read moreSee 2 more doctor answers
Abdominal organ. It is digestive organ: it secretes enzymes into the small bowel which break down food and help its absorption. It is also an endocrine organ: it produces hormones involved in sugar control and control of digestion. Insulin is one of these hormones. Diabetics either lack Insulin (type 1 diabetes) or have inadequate ...Read more
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