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Doctor insights on: Pancreatic Polypeptide

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How accurate is pancreatic polypeptide In detecting pancreas tumor?

How accurate is pancreatic polypeptide
In detecting pancreas tumor?

NOT VERY!!!: Hi. Pancreatic polypeptide (PP) is NOT a screening test for pancreatic tumors. The only pancreatic cells that make PP are rare neuroendocrine cells in the Islets of Langerhans (an already tiny fraction of the pancreas). And those would be a TINY, TINY fraction of all pancreatic tumors. But hey, if it's a PP secreting neuroendocrine tumor of the pancreas, you'd have it dialed! Good luck! ...Read more

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Dr. Neigatha Graney
3 doctors shared insights

Pancreas (Definition)

Abdominal organ. It is digestive organ: it secretes enzymes into the small bowel which break down food and help its absorption. It is also an endocrine organ: it produces hormones involved in sugar control and control of digestion. Insulin is one of these hormones. Diabetics either lack Insulin (type 1 diabetes) or have inadequate ...Read more


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How accurate is pancreatic polypeptide In detecting pancreas tumor?

NOT VERY!!!: Hi. Pancreatic polypeptide (PP) is NOT a screening test for pancreatic tumors. The only pancreatic cells that make PP are rare neuroendocrine cells in the Islets of Langerhans (an already tiny fraction of the pancreas). And those would be a TINY, TINY fraction of all pancreatic tumors. But hey, if it's a PP secreting neuroendocrine tumor of the pancreas, you'd have it dialed! Good luck! ...Read more

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I have primary hyperparathyroidism. My lipase and amylasec ranges from borderline high to x 6 u.L. Since 2006. The pancreatic polypeptide was x 3 u.L. In 2013. The CT wasnormal. Could I have neuroendocrine tumor or men-1?

I have primary hyperparathyroidism. My lipase and amylasec ranges from borderline high to x 6 u.L. Since 2006. The pancreatic polypeptide was x 3 u.L. In 2013. The CT wasnormal. Could I have neuroendocrine tumor or men-1?

Not unlikely: Neuroendocrine tumors can be difficult to detect. If the symptoms persist or worsen, there are more sophisticated imaging modalities available to look for occult tumors, including gallium 68. If you have other family members who have been diagnosed with pancreatic or adrenal tumors and/or hyperparathyroidism, men1 would be possible. ...Read more

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Is insulin a polypeptide or a protein?

Is insulin a polypeptide or a protein?

Definition: Hi. A definition was decided arbitrarily long ago, in the infancy of biochemistry, that proteins are 50 or more amino acids, and polypeptides are 49 or fewer. Insulin is a 51 amino acid polypeptide, and therefore, a protein. But it's completely arbitrary, and the chemistry of insulin doesn't care if you call it a protein or a polypeptide. But insulin rocks, eh?! ...Read more

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What's vasoactive intestinal polypeptide vip?

What's vasoactive intestinal polypeptide vip?

VIP definition: Vasoactive intestinal peptide or vip is a peptide hormone containing 28 Amino Acid residues. Vip is produced in many tissues of vertebrates including the gut, pancreas and suprachiasmatic nuclei of the hypothalamus in the brain. Vip stimulates contractility in the heart, causes vasodilation, increases glycogenolysis, lowers arterial blood pressure and relaxes the smooth muscle of trachea & stomach. ...Read more

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What are the benefits of taking collagen capsules? 4 capsules daily. Hydrolyzed marine collagen and elastin polypeptides.

What are the benefits of taking collagen capsules? 4 capsules daily. Hydrolyzed marine collagen and elastin polypeptides.

Not much evidence: There aren't a lot of studies out that have tested the health effects of all these collegen supplements.One study found that it does not really help with bone health,and another showed some preservation of lean body mass in older women but no skin improvement.It seems that elastin skin products have not shown clinically to improve elasticity of the skin but do help the skin hold moisture. ...Read more

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Can you tell me how the hbs polypeptide reduce oxygen transport in sickle cell disease?

Can you tell me how the hbs polypeptide reduce oxygen transport in sickle cell disease?

Some info: Hemolobin S produces what are known as hemoglobin tactoids-gelations of hemoglobin which are not as able to release oxygen because of mechanical reasons. ...Read more