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Doctor insights on: Pancreatic Polypeptide

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How accurate is pancreatic polypeptide In detecting pancreas tumor?

How accurate is pancreatic polypeptide
In detecting pancreas tumor?

NOT VERY!!!: Hi. Pancreatic polypeptide (PP) is NOT a screening test for pancreatic tumors. The only pancreatic cells that make PP are rare neuroendocrine cells in the Islets of Langerhans (an already tiny fraction of the pancreas). And those would be a TINY, TINY fraction of all pancreatic tumors. But hey, if it's a PP secreting neuroendocrine tumor of the pancreas, you'd have it dialed! Good luck! ...Read more

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Dr. Gregory Moneta
3 doctors shared insights

Pancreas (Definition)

Abdominal organ. It is digestive organ: it secretes enzymes into the small bowel which break down food and help its absorption. It is also an endocrine organ: it produces hormones involved in sugar control and control of digestion. Insulin is one of these hormones. Diabetics either lack Insulin (type 1 diabetes) or have inadequate ...Read more


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How accurate is pancreatic polypeptide In detecting pancreas tumor?

NOT VERY!!!: Hi. Pancreatic polypeptide (PP) is NOT a screening test for pancreatic tumors. The only pancreatic cells that make PP are rare neuroendocrine cells in the Islets of Langerhans (an already tiny fraction of the pancreas). And those would be a TINY, TINY fraction of all pancreatic tumors. But hey, if it's a PP secreting neuroendocrine tumor of the pancreas, you'd have it dialed! Good luck! ...Read more

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I have primary hyperparathyroidism. My lipase and amylasec ranges from borderline high to x 6 u.L. Since 2006. The pancreatic polypeptide was x 3 u.L. In 2013. The CT wasnormal. Could I have neuroendocrine tumor or men-1?

I have primary hyperparathyroidism. My lipase and amylasec ranges from borderline high to x 6 u.L. Since 2006. The pancreatic polypeptide was x 3 u.L. In 2013. The CT wasnormal. Could I have neuroendocrine tumor or men-1?

Not unlikely: Neuroendocrine tumors can be difficult to detect. If the symptoms persist or worsen, there are more sophisticated imaging modalities available to look for occult tumors, including gallium 68. If you have other family members who have been diagnosed with pancreatic or adrenal tumors and/or hyperparathyroidism, men1 would be possible. ...Read more

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Is insulin a polypeptide or a protein?

Is insulin a polypeptide or a protein?

Definition: Hi. A definition was decided arbitrarily long ago, in the infancy of biochemistry, that proteins are 50 or more amino acids, and polypeptides are 49 or fewer. Insulin is a 51 amino acid polypeptide, and therefore, a protein. But it's completely arbitrary, and the chemistry of insulin doesn't care if you call it a protein or a polypeptide. But insulin rocks, eh?! ...Read more

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What's vasoactive intestinal polypeptide vip?

What's vasoactive intestinal polypeptide vip?

VIP definition: Vasoactive intestinal peptide or vip is a peptide hormone containing 28 Amino Acid residues. Vip is produced in many tissues of vertebrates including the gut, pancreas and suprachiasmatic nuclei of the hypothalamus in the brain. Vip stimulates contractility in the heart, causes vasodilation, increases glycogenolysis, lowers arterial blood pressure and relaxes the smooth muscle of trachea & stomach. ...Read more

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What are the benefits of taking collagen capsules? 4 capsules daily. Hydrolyzed marine collagen and elastin polypeptides.

What are the benefits of taking collagen capsules? 4 capsules daily. Hydrolyzed marine collagen and elastin polypeptides.

Not much evidence: There aren't a lot of studies out that have tested the health effects of all these collegen supplements.One study found that it does not really help with bone health,and another showed some preservation of lean body mass in older women but no skin improvement.It seems that elastin skin products have not shown clinically to improve elasticity of the skin but do help the skin hold moisture. ...Read more

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Can you tell me how the hbs polypeptide reduce oxygen transport in sickle cell disease?

Can you tell me how the hbs polypeptide reduce oxygen transport in sickle cell disease?

Some info: Hemolobin S produces what are known as hemoglobin tactoids-gelations of hemoglobin which are not as able to release oxygen because of mechanical reasons. ...Read more

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DERMATOLOGISTS: Will taking collagen capsules help with fine lines over time? Ingredients:hydrolyzed marine collagen, elastin polypeptides

I really doubt it.: Protein is digested and absorbed. It's doubtful that a small amount of a particular protein is going to be 'special' compared to a burger. Less collagen, degraded protein loss of subcutaneous fat are aging features that promote crow's feet and specific dietary proteins just aren't going to change any of that. ...Read more

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How do I treat inflame pancreas?

How do I treat inflame pancreas?

Pancreatitis info: Hi QFong, If you have been diagnosed with pancreatitis, I would recommend that you seek treatment guided by a physician as soon as possible. The treatment is fairly simple but you need work up to determine the cause and to be monitored clinically depending on the severity of your illness. Here is some additional information. I hope this answers your questions. http://wb.md/2gWMgUZ ...Read more

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How can you affect your pancreas?

How can you affect your pancreas?

Pnacreas: I wish I could help but you have not given any information. What exactly do you mean by "affect your pancreas"? ...Read more

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What service does a pancreas perform?

Multiple functions: On one hand, it produces several enzymes needed to digest food. This is the "exocrine" part of the pancreas. On the other hand, there is an "endocrine" part that is responsible of the levels of blood sugar (through the release of Insulin and glucagon). It also release other hormones. ...Read more

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How do the islets in the pancreas work?

How do the islets in the pancreas work?

Make hormones.: The islets of langerhans in the pancreas contain its endocrine cells. These cells produce hormones that help control blood glucose levels in the body. There are at least 5 kinds of islet cells: Alpha cells producing glucagon (15-20% of cells), beta cells - Insulin and amylin (65–80%), delta cells - somatostatin (3–10%), pp cells - pancreatic polypeptide (3–5%), epsilon cells -ghrelin (<1%). ...Read more

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Where is the pancreas in the body found?

Where is the pancreas in the body found?

Deep in the belly: The pancreas is located in the upper abdomen, behind the stomach, and in front of the spine. On the right side, the pancreas is bounded by the duodenum (small intestine), and on the left side it is bounded by the spleen. There are several very large blood vessels that touch the pancreas as well. This challenging anatomy demands that a specialist operate on the pancreas. ...Read more

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What side of the body is your pancreas on?

Middle: the pancreas is usually right in the middle of the abdomen, just above your belly button. Why do you ask? ...Read more

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Can the pancreas be tottally removed safely?

Can the pancreas be tottally removed safely?

Not really: Very rarely, such as in emergencies or specific types of pancreatic cancer. The pancreas is responsible for producing major hormones involved in sugar regulation and digestion- removal would take away all of these hormones. The pancreas is also located very close to major blood vessels and vital organs, making the surgery difficult. ...Read more

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What is the best medicine for pancreas pain?

Metformin: Metformin sometimes relieves pancreatic pain by acting as an insulin receptor sensitizer, thereby reducing the requirement for the pancreas to work so hard to release insulin. It's not a pain reliever, per-se, but gives the pancreas a "rest," reducing pancreatic action which often reduces the pain. ...Read more

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What are the symptoms of a pancreas problem?

Pancreas: Besides pain there is little to note about the pancreas. I am curious as to what is the rest of the story. What is the question you are really asking? ...Read more

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What are some common causes of pancreatic pain?

What are some common causes of pancreatic pain?

Inflammation: Pancreatitis, which is an inflammatory, very painful and dangerous conditions, stones stuck in the duct that drains pancreas and a complication from pancreatitis called pseudo cyst of the pancreas. Cancer may or may not cause pain. ...Read more

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What are the hallmarks of good pancreas health?

What are the hallmarks of good pancreas health?

Pancreas health: I don't fully understand the question. If the pancreas is working OK there should be no concern. If the pancreas has stopped working careful replacement medication is in order. If the pancreas has some tumors in it they need to be removed. ...Read more

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What is the definition or description of: pancreas?

Abdominal organ: Abdominal organ. It is digestive organ: it secretes enzymes into the small bowel which break down food and help its absorption. It is also an endocrine organ: it produces hormones involved in sugar control and control of digestion. Insulin is one of these hormones. Diabetics either lack Insulin (type 1 diabetes) or have inadequate Insulin function (type 2). ...Read more

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Can exorcine pancreatic insufissancy, not have any cause?

Pancreatic insuf: The exocrine pancreas produces 3 main types of enzymes: amylase, protease, and lipase. Because the exocrine pancreas retains a large reserve capacity for enzyme secretion, fat digestion is not clearly impaired until lipase output decreases to below 10% of the normal level. The diagnosis is clinical. It may go undetected due to dietary restrictions. ...Read more