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Doctor insights on: Pancreatic Exocrine Cell Ab

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Dr. Michael Gabor
3 doctors shared insights

Pancreas (Definition)

Abdominal organ. It is digestive organ: it secretes enzymes into the small bowel which break down food and help its absorption. It is also an endocrine organ: it produces hormones involved in sugar control and control of digestion. Insulin is one of these hormones. Diabetics either lack Insulin (type 1 diabetes) or have inadequate ...Read more


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What distinguishes pancreas, liver, colon, kidney, prostate and gallbladder cancers?

What distinguishes pancreas, liver, colon, kidney, prostate and gallbladder cancers?

Cure varies: Beyond the obvious differences in organ and cell type as well as the various treatment approaches, the most important patient difference is really the chance at cure. Early stage prostate and renal cell (kidney) cancers can be very curable. Even really early stage pancreatic cancers can be quite deadly. ...Read more

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Which genes control cell growth in pancreatic tissue?

Which genes control cell growth in pancreatic tissue?

There are: literally millions of genes that control cell growth not only in pancreatic tissue but throughout the entire body. Why do you ask? ...Read more

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How accurate is pancreatic polypeptide In detecting pancreas tumor?

How accurate is pancreatic polypeptide
In detecting pancreas tumor?

NOT VERY!!!: Hi. Pancreatic polypeptide (PP) is NOT a screening test for pancreatic tumors. The only pancreatic cells that make PP are rare neuroendocrine cells in the Islets of Langerhans (an already tiny fraction of the pancreas). And those would be a TINY, TINY fraction of all pancreatic tumors. But hey, if it's a PP secreting neuroendocrine tumor of the pancreas, you'd have it dialed! Good luck! ...Read more

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What about neuroendocrine (islet cell tumors)?

What about neuroendocrine (islet cell tumors)?

Interesting tumor: Overally, neuroendocrine tumors are often capable of over-producing hormones that your body naturally makes. Islet cells are cells that are naturally present in the pancreas and produce a number of hormones, most notably insulin. Insulin helps you break down and digest sugars. Patients with an islet cell tumor can produce too much Insulin resulting in weight & gain and low blood sugars. ...Read more

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Which test is better for diagnosing pancreas insufficiency: stool panc elastase or serum lipase/amylase? Would either diagnose pancreatic cancer?

Which test is better for diagnosing pancreas insufficiency: stool panc elastase or serum lipase/amylase? Would either diagnose pancreatic cancer?

Both together: Neither of the tests alone tells much. A combination of tests and exams will lead to diagnosis. Pancreatic cancer is not able to be ruled out by any test or imaging study. It can only be absolutely proven by some form of biopsy. A ct guided needle or egd with brushing a may be the only way to find it. ...Read more

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Normal pancreatic enzymes, normal liver enzymes, normal CBC, normal ESR & C-RP. does this rule out pancreatic and liver cancer?

Normal pancreatic enzymes, normal liver enzymes, normal CBC, normal ESR & C-RP. does this rule out pancreatic and liver cancer?

Why do you ask?: Why would you think you have this stuff at age 20? You've written about this before. You owe it to yourself and those who love you to get with someone who can help you out these thoughts out of your mind and get on with studying, getting job skills and experience, perhaps finding romance and meaningful things to enjoy. To be brave, act brave. You're anything but helpless. ...Read more

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Can pancreatic/biliary duct, stomach, colon cancer or leukemia skip a generation?

Can pancreatic/biliary duct, stomach, colon cancer or leukemia skip a generation?

Variable: Family incidence doesn't mean you will have the disease only that you MAY get it and should be more vigilant. For example colon cancer. Start colonoscopy at age 30 rather than 50, etc.. ...Read more

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Pancreatic cancer. Whipple. Chemo 7 months. Tumors in pancreas and liver. Recent blood clot. Pain. New intestinal blockage. Is my body shutting down?

Pancreatic cancer. Whipple. Chemo 7 months. Tumors in pancreas and liver. Recent blood clot. Pain. New intestinal blockage. Is my body shutting down?

Difficult disease: Some blockages are due to scar tissue inside the abdomen (called adhesions), and other blockages are due to cancer growth. A CT scan may be able to tell the difference between the 2. If the blockage is cancer-related, then it may be time to think about a different chemotherapy regimen. But if it's just adhensions, then sometimes an operation helps. Talk to your doctor to investigate further ...Read more

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Panc elastase test shows insufficiency. Have fatty liver. Is pei cause of fatty liver? Is there connection between fatty liver and pancreatic cancer?

Panc elastase test shows insufficiency. Have fatty liver. Is pei cause of fatty liver? Is there connection between fatty liver and pancreatic cancer?

No, just description: Like most dx, just a label for a pattern, as judged by whatever metrics. Yes, there is observed relation between fatty liver ; developing liver cancer. Fatty liver most commonly due to persistent low-fat, hi-carb (i.e. All sugars, simple ; complex) foods. Liver, to protect rest of body from ?sugar (toxic), converts sugars into triglyceride fats. If can't export into external fat, then fatty liver. ...Read more

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How to diagnose pancreatic dysfunction? Amylase, lipase and insulin blood test?

History & physical: If the pancreas is inflamed or damaged, amylase and lipase are often up, and it's not subtle. If your pancreas isn't functioning properly, you'll be losing weight with no explanation and probably have diarrhea / steatorrhea. Your physician can check your stool for pancreatic enzymes. It's rare but with a suggestive history, a screen may show something that could respond to enzyme replacement. ...Read more

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A friend w/ advanced pancreatic cancer. Chemo helped. Tumors in pancreas & liver. Intrathecal pump. Digestion problems. Released to go home. Hospice?

A friend w/ advanced pancreatic cancer. Chemo helped. Tumors in pancreas & liver. Intrathecal pump. Digestion problems. Released to go home. Hospice?

Advanced cancer: It seems reasonable and sensitive to engage hospice; hospice can help at home or he can go to a facility; hospice team can engage for many weeks. It is a good service. ...Read more

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Necrotiz pancreat led to chronic pancreas 5 yrs. EUS shows markedly atrophic pancreas. taking pancreaze 10500 units x 12/day w/food. Extreme fatigue!

Necrotiz pancreat led to chronic pancreas 5 yrs. EUS shows markedly atrophic pancreas. taking pancreaze 10500 units x 12/day w/food. Extreme fatigue!

Talk to your doctor!: You have a complicated health history and should be following closely with a GI physician. Talk to them! Your symptoms can't be properly evaluated in an anonymous question format and you owe it to yourself to be completely open with your physicians about how you are feeling and your concerns. They can't evaluate an issue that you don't share with them. ...Read more

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Are liver and pancreatic enzymes always elevated with liver and pancreatic cancer?

Are liver and pancreatic enzymes always elevated with liver and pancreatic cancer?

Short answer: No: Most often if a malignant mass presses on the ductal system of liver or panc. (see picture), it can cause abn. blood enzymes. If the mass is small and ducts drain, routine enzymes are usually normal. Gilbert Syndrome, a genetic abn. of up to 7% of folks, has the significance like your fingerprints, and is discussed nicely in: http://ghr.nlm.nih.gov/condition/gilbert-syndrome ...Read more

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Hepatocellular carcinoma.All spleen and partial liver resection.Later,secondary systemic cancer metastasis.any targeted therapy or immunotherapy?

Hepatocellular carcinoma.All spleen and partial liver resection.Later,secondary systemic cancer metastasis.any targeted therapy or immunotherapy?

Yes, for both: Hepatocellular Carcinoma is commonly treated with Sorafenib which is a type of targeted therapy. This is a good choice of treatment in case you have not yet received this drug. Immunotherapy using PD-1 inhibitors has also shown some modest evidence of benefit although it is not yet FDA approved for this indication. Ask your oncologist to guide your treatment further. ...Read more

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Pancreatic cancer?I had a pancreatic protocol ct/hida/liver, pancreas, CBC blood test/stool test/colonoscopy.All perfect.I still have light/yellow stool

Pancreatic cancer?I had a pancreatic protocol ct/hida/liver, pancreas, CBC blood test/stool test/colonoscopy.All perfect.I still have light/yellow stool

Stop worrying: You have nothing to worry about except that fact that you are still a smoker, which i hope you'll stop. If everybody with light-colored stools consumed health-care dollars searching for pancreatic cancer, it'd be a huge waste. Evidently you're not even jaundiced. Please stop reading internet scare stuff, look for another cause of your abdominal pain ; stop reading internet scare stuff. ...Read more

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7mm periampullary lesion, 3 liver lesions, total beta hCG is high, anion gap-10, monocytes-1.1, chloride high, erc low, cbd & pancreatic duct dilation?

7mm periampullary lesion, 3 liver lesions, total beta hCG is high, anion gap-10, monocytes-1.1, chloride high, erc low, cbd & pancreatic duct dilation?

Your question?: I appreciate your sharing this, but no one here will be able to make the call. Unless your HCG is extremely high, it means nothing. The other labs are not helpful. Your periampullary lesion has hopefully been biopsied, as will your liver lesions if the radiologist cannot certify them as benign. Hoping celiac sprue has been ruled in or out, along with whipple's and common lactose intolerance. ...Read more

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Tiny adrenal tumor, h cortisol, h testosterone, h creatinine, h dheas, fast gluc 106. Hysterectomy, thyromegaly Will metformin reduce testosterone?

Tiny adrenal tumor, h cortisol, h testosterone, h creatinine, h dheas, fast gluc 106.   Hysterectomy, thyromegaly
Will metformin reduce testosterone?

Hormones: Metformin medicine that keeps your blood sugar under control should not have an effect on testosterone. That said, too much metformin will likely lower your testosterone. Are you checking your blood sugar regularly? Please let me know how things are going. ...Read more