Doctor insights on:
Pancreatic Cancer Prognosis Without Treatment
Plenty of Rx: But only total removal works. Panc resides in a critical area, if ca invades important vessels removal unlikely. Potential to remove improved with chemo and radiorx. If vessels not freed, stomach and liver secretions need to be bypassed to attain relief. ...Read more
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
Unfortunately, conventional therapy has poor success. Alternative therapies are controversial but are worth considering- see www. Cancertutor. Com for an overview. For pancreatic cancer specifically, oncologist nicholas gonzales offers a promising if controversial approach: www. Dr-gonzalez. Com a recent study on homeopathic psorinum had incredible results:
www. Hindawi. Com/journals/ecam/2011/724743. ...Read more
Perhaps: Whenever one of my patients wants to use natural or alternative therapy for a problem. I always ask them to show me exactly what it is they are taking. Some things may help, some things may really do nothing at all, but some things may have bad side effect when combine with other medicines. Your doctor can cross check your alternative medicines with whatever they order. ...Read more
In addition to gemcitabine, are there any new treatments for advanced pancreatic cancer (in older people)?
Cyberknife: Aggressive local treatment in addition to chemotherapy has offered good palliation of the symptoms and improvement of local control. Use of cyberknife radiosurgery in elderly with advanced pancreatic cancer patients is usually very well tolerated and improves local control and can offer palliation if patient is symptomatic. Gemzar (gemcitabine) alone or in combination with 5-fu mainstay of systemic therapy. ...Read more
Gene therapy for cancers, including pancreatic cancer is not in common use. See this site for more info.
http://www. Mayoclinic. Com/health/gene-therapy/my00105. ...Read more
My son has pancreatic cancer. It has moved to the lymph nodes. Generally what is the prognosis? He is 39.
Depends: For the 85% or so of patients who present with disease that cannot be resectable, survival is usually 6 months or less without treatment and around a year with aggressive chemo +/- radiation. Surgery with negative lymph nodes has about a 25% 5-year survival rate with chemo and radiation. Surgery with positive nodes - about 14 months average with chemo and radiation. ...Read more
Pancreatic cancer, ampullary tumor. Whipple procedure. Spread to liver, not respectable. Chemo for 6 months and continuing. Prognosis?
Poor: While Whipple is the best approach for a primary pancreatic or ampullary lesion, the recurrence rate at 1-2 yrs is 90%. Chemo either of the FOLFIERI or Genciabine /Abraxane combo have limited effects on liver mets which in pancreas are not considered amenable to resection. There is an FDA protocol using specific monoclonals targeting pancreas that might be available but only after chemo failure ...Read more
Doesn't exist: After failing chemo which all pancreatic malignancies do, a newer approach is using monoclonal antibodies targeting an immunogenic protein, a post translational modification of MUC5ac, to bring the tumor under control. With the proper dosage, added chemo and later the radiolabelled Alpha emitter given sequentially, better results are anticipated. ...Read more
Unsure of question!: Do YOU have pancreas cancer? That is very rare in someone in their 30s. No one knows what causes pancreas cancer. Symptoms are usually upper mid-abdominal pain near the breast bone, often after eating going into the back, weight loss, loss of appetite, change in taste/smell sensation, blood clot in leg, depression. Early pancreas cancer's best chance for cure is surgery. ...Read more
What is the worst disease a person can be diagnosed with? Low cure rate, fatal, and very aggressive. ALS? Pancreatic cancer? Something else?
"Worst disease" means nothing without more information.
It is time to see your doctor who will take your medical history, examine you, and then possibly/probably will order labs.
When complete the doctor will discuss things with you. ...Read more
Surgery is Key:
The best option for cure is surgery. About 20% of patients with pancreatic cancer are candidates for surgery. The surgery is pancreaticoduodenectomy, also called a Whipple procedure. It usually involves removing.
1. The head of the pancreas
2. A part of the duodenum
3. A of a portion of the common bile duct
4. The gall bladder
5. In many instances a portion of the stomach ...Read more
Surgical oncology: Whipple may be the only cure for pancreatic cancer? But, it is a huge operation with many months of recovery? Go through it?
Depends: You are right, a Whipple is a big operation. Fortunately, many patients have a great outcome and the recovery is generally about 8 weeks, not always "many months". True, if you have a complication, it can take this long. It really depends how strong you are going into the operation, the anatomy of your cancer, and your cancer stage. Talk with your surgeon. ...Read more
No: If the diagnosis is correct, then they want to play you for a fool. Please forgive my frankness, and call me unspiritual if you want. It is hard enough to have incurable cancer -- harder still to be taken for thousands of dollars by sweet-talkers who may themselves be deceived. If you realize you have been scammed, call your local prosecutor -- i'll testify for free if it will help. ...Read more
Chemotherapy: Treatment of pancreatic cancer like many cancers involves surgical oncologists (surgery), medical oncologists (chemotherapy) and radiation oncologist (radiation). Chemotherapy is usually Gemzar (gemcitabine) or 5-fu based. There are some existing new drug combinations recently that has helped improve outcomes. ...Read more
If you are: In boston, you have some of the best hospitals in the country within your city. Ask your doctor for a referral. ...Read more
Immunochemotherapy: Stage IV pancreatic cancer is a poor responder due to excessive Kras mutations and release of TNF which is same as cachexin causing several metabolic problems. Best approach is to begin with FOLFIERI followed by Gemzar (gemcitabine) Abraxane. New Phase IIb study will begin comparing Gemzar (gemcitabine)/Abrtaxane vs. Gemzar (gemcitabine) Abraxane with a monoclonal antibody targeting the immunogenic protein found in pancreatic cancer. ...Read more
Resection: There are basically two types of surgery for pancreatic cancer: as mentioned, tumors in the head of the pancreas are removed by resection of the head of the pancreas, duodenum, and distal bile duct (the whipple); tumors in the body and tail are removed by distal pancreatectomy, often with splenectomy. All pancreatic resections should be performed at high volume centers by high volume surgeons. ...Read more
IS COMPLEX: Myasthenia gravis affects the connection btwn nerve and muscle, and control is achieved by dealing with an autoimmune process. If surgery is to be done, oral meds will need to be held, and postop respiratory failure may occur especially if surgery requires a neuro-muscular blocking agent. Some anesthetics can worsen myasthenia, chemotherapy may be tough. A skilled neurologist needs to be nearby. ...Read more
Depends on stage: Colon ca: stage 1 (surgery, no chemo), stage 2 (surgery, usually no chemo), stage 3 (surgery, chemo), stage 4 (chemo, surgery and radiation only for symptom control). Pancreas staging is often defined functionally as "resectable" (surgery as primary treatment), "borderline/unresectable" (neo-adjuvant chemo and surgery if possible), advanced/metastatic (chemo). Details too advanced for answer limit. ...Read more
Pain relief and: Supportive with comfort care (hospice)Get a more detailed answer ›
Recuperating from pancreatic cancer and was advised to change from pan crease to pancrelipase. Is that favorable treatment?
Yes: Recuperating means treatment other than chemo. If Whipple performed the duct of the pancreas was implanted into the bowel to allow enzymes to pass into the GI tract. The amt of enzyme for digestion is usually low and one needs both the proteins and fat digested with the add of bile from the liver/GB. The pancrelipase provides that function. ...Read more
What effects might myasthenia graves have on radiation and chemotherapy treatment for pancreatic cancer?
See prior answer: In brief, anesthesia, neuromuscular blockers, surgery itself can all result in post-operative respiratory failure, with need for trach and respirator. The chemo may also affect the neuromuscular junction. Need a careful coordinated team approach with your neurologist constantly monitoring. ...Read more
Hi, if pet scan results for pancreatic cancer are negative after treatment is this mean that the patient was recovered completely?
No: The medical definition of a cure is usually no cancer present for 5 years after the end of treatment. PET scans can miss small tumors and can also give a falsely negative results for other reasons. That being said, it is a positive sign, better chance of a cure than if cancer were still present, obviously. ...Read more
My dad has pancreatic cancer that has spread to his liver. Chemo did not help. How long can he live without further treatment?
Palliative Care: Survival rates are most appropriately applied to large groups of patients; it's impossible to give such a number for one person, especially without knowing his own unique situation. As a generalization, it is very difficult to completely eradicate cancer in that setting. The fact that he has not responded to chemotherapy would suggest that the focus should be on palliative (comfort) care. ...Read more
Why have there been no major breakthroughs in pancreatic cancer treatment? Why is it so hard to come up with a good screening tool?
My dad has pancreatic cancer that spread to his liver. Chemo did not help. The cancer has spread more. How long can he live without further treatment?
Few months at best: Most pateints with metastatic pancreatic cnacer die within 6 months to 12 months. So given that he has liver metastases and already failed chemo, he may not live more than 1, 2 or 3 months. But it is not possible to predict it exactly. ...Read more
Abdominal organ. It is digestive organ: it secretes enzymes into the small bowel which break down food and help its absorption. It is also an endocrine organ: it produces hormones involved in sugar control and control of digestion. Insulin is one of these hormones. Diabetics either lack Insulin (type 1 diabetes) or have inadequate ...Read more
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