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Doctor insights on: Pancreas Transplantation

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Dr. Jonathan Fridell
71 doctors shared insights

Pancreas Transplantation (Overview)

Type 1 diabetics do not make insulin, but if they get a transplant, the new pancreas would make Insulin and the sugars would be normal. It is like having a biologic Insulin pump that works perfectly. It is not a cure, but it is currently the most effective treatment available. The downside: it involves a big operation, lifelong immunosuppresion and is only offered to select individuals.


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I have severe sharp pain as soon as I begin to eat. The pain is NOT my stomache but just to the left of my stomache. Exactly where the pancrease (pancrelipase) sits.

I have severe sharp pain as soon as I begin to eat. The pain is NOT my stomache but just to the left of my stomache. Exactly where the pancrease (pancrelipase) sits.

Few possibilities: There are a few possibilities from pancreatic issues, to ulcers, and possibly gall bladder. See your doc or make an appointment with HealthTap to provide more detail. I'm available through the Concierge service all day. ...Read more

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Dr. Jonathan Fridell
71 doctors shared insights

Pancreas Transplantation (Overview)

Type 1 diabetics do not make insulin, but if they get a transplant, the new pancreas would make Insulin and the sugars would be normal. It is like having a biologic Insulin pump that works perfectly. It is not a cure, but it is currently the most effective treatment available. The downside: it involves a big operation, lifelong immunosuppresion and is only offered to select individuals.


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What is the definition or description of: pancreas transplantation?

What is the definition or description of: pancreas transplantation?

Pancreas transplant: Type 1 diabetics do not make insulin, but if they get a transplant, the new pancreas would make Insulin and the sugars would be normal. It is like having a biologic Insulin pump that works perfectly. It is not a cure, but it is currently the most effective treatment available. The downside: it involves a big operation, lifelong immunosuppresion and is only offered to select individuals. ...Read more

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Is it possible have a pancreas transplant?

Is it possible have a pancreas transplant?

Yes: In the us over 1000 were done last year. About 800 are combined with a kidney transplant in those diabetics that also have kidney failure. ...Read more

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Why is a pancreas transplant never heard of?

Why is a pancreas transplant never heard of?

It is: There are two common indications for a pancreas transplant: 1. A commitment to lifelong immunosuppresion for another organ transplant in a type 1 diabetic (usually a kidney for diabetic nephrology, but liver and lung have been done as well) or 2. Very poorly controlled type 1 diabetes despite optimized medical care. This usually requires documented episodes of hypoglycemia unawareness. ...Read more

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What is the success in a pancreas transplant?

What is the success in a pancreas transplant?

Results: The international pancreas transplant registry (iptr) and the organ procurement and transplant network (optn) have data available on line. 1 yr pt survival ranges from 95.5-97.4. Graft survival at 1 yr is 78-85 depending on type of transplant with the best results reported for spk. Some centers are reporting 1 year graft survival rates in the 89-90% range with certain immunosuppresion regimens. ...Read more

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Is it possible to have a pancreas transplant?

Is it possible to have a pancreas transplant?

Yes: Hi. Yes, it is. They generally only do them when they're also doing a kidney transplant for kidney failure from diabetic kidney disease, although that standard is shifting some. Transplants require immunosupression, which most docs will tell you is a boat load worse than taking insulin shots. To your health! ...Read more

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When is it too risky for a pancreas transplant?

When is it too risky for a pancreas transplant?

Refer to your doctor: Every situation is different. Your surgeon must assess your general medical condition before deciding on the level of risk. ...Read more

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Would it be possible to have a pancreas transplant?

Would it be possible to have a pancreas transplant?

Yes, for diabetes: Pancreas transplants are done for type 1 diabetes (rarely for type 2) that has caused kidney failure, or causes unawareness of hypoglycemia. Few good quality organs are available and the risks are greater than for a kidney transplant. So, only about 1000 are performed each year in the us. The purpose of the txp is to normalize blood sugar without the need to use insulin. ...Read more

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What risks are associated with pancreas transplant ?

What risks are associated with pancreas transplant ?

Surgical risks: The risks involved with pancreas transplant involve the risks of surgery. The risks involve death, bleeding, infection, nerve injury, loss of graft function. The risks also involve that of anesthesia. These benefits are that you are freed from Insulin and the stability of sugar level. Talk to your doctor about the risks and benefits. ...Read more

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Why is it not possible to have a pancreas transplant?

It's possible: But there are strict criteria as to who would benefit. Talk to a diabetologist. ...Read more

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If i recieve a pancreas transplant could i join the army?

NPQ: A pancreatic transplant would prevent enlistment or commissioning in any branch of the armed forces. You would be "not physically qualified". ...Read more

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Can pancreas transplant be possible with today's technology?

Absolutely: There are over 1000 done every year in the us. While the majority also have uremia-kidney failure- several hundred do not. Speak with you transplant team or contact the american society of transplant surgeons for centers. ...Read more

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Can it be possible for someone to have a pancreas transplant?

Can it be possible for someone to have a pancreas transplant?

Yes: It is possible to have a whole organ pancreas transplant, in diabetics often done in conjunction with kidney transplantation. It is also possible to have pancreatic islet cell transplantation, which in some cases is considered experimental. The best option would depend on what the problem is with the pancreas and what other treatments are planned. ...Read more

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Can you tell me how to get on the waiting list for a pancreas transplant?

First an evaluation: Call one of the local transplant centers in your location and make an appointment to be evaluated. You can contact the american society of transplant surgeons for a center in your area. Not every diabetic is a good candidate for the procedure and you will need careful evaluation and discussion of benefits and risks. ...Read more

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I'm wondering why can't diabetics have a pancreas transplant?

I'm wondering why can't diabetics have a pancreas transplant?

They can: But then they have to be on transplant medications that are sometimes more dangerous than diabetes. There are also many complications that can occur so its usually reserved for diabetic patients that are young who can't control their diabetes on the diabetic medications. ...Read more

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Can a diabetic request a pancreas transplant?

Pancreas transplant: There are two common indications for a pancreas transplant: 1. A commitment to lifelong immunosuppresion for another organ transplant in a type 1 diabetic (usually a kidney for diabetic nephrology, but liver and lung have been done as well) or 2. Very poorly controlled type 1 diabetes despite optimized medical care. This usually requires documented episodes of hypoglycemia unawareness. ...Read more

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Can having a pancreas transplant cure type 1 diabete?

Can having a pancreas transplant cure type 1 diabete?

Pancreas transplant: Type 1 diabetics do not make insulin, but if they get a transplant, the new pancreas would make Insulin and the sugars would be normal. It is like having a biologic Insulin pump that works perfectly. It is not a cure, but it is currently the most effective treatment available. The downside: it involves a big operation, lifelong immunosuppresion and is only offered to select individuals. ...Read more

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What can I expect with kidney and pancreas transplant?

What can I expect with kidney and pancreas transplant?

Feeling healthy : When a kidney + pancreas transplant is successful (roughly 4 our 5 cases) the diabetic patient becomes free from needing Insulin or having to check blood sugar. If dialysis was needed pre-txp, that also becomes unnecessary. Overall, the person feels rejuvenated and healthy again. But risks must be considered too. They include surgical complications, rejection, and the need for immunosuppression. ...Read more

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I am a type 1 diabetic. Can i sign up for a pancreas transplant ?

I am a type 1 diabetic. Can i sign up for a pancreas transplant ?

Pancreas transplant: There are two common indications for a pancreas transplant: 1. A commitment to lifelong immunosuppresion for another organ transplant in a type 1 diabetic (usually a kidney for diabetic nephrology, but liver and lung have been done as well) or 2. Very poorly controlled type 1 diabetes despite optimized medical care. This usually requires documented episodes of hypoglycemia unawareness. ...Read more

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Can it be possible for a diabetic to request a pancreas transplant?

Can it be possible for a diabetic to request a pancreas transplant?

Yes: In diabetics a pancreas transplant is often performed together with a kidney transplant. There is also research into using pancreatic islet cell transplantation which is less invasive usually than a whole organ transplantation in diabetics to restore beta cell function (the Insulin producing cells of the pancreas.). ...Read more

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Can someone who is diabetic get a pancreas transplant and be cured?

Can someone who is diabetic get a pancreas transplant and be cured?

Not completely: Pancreas transplant will replace the needed Insulin for the patient, but does not really cure the diabetes. One reason is the disease has been present for years-even decades-and has taken a toll on the blood vessels and other organs and tissues of the body. ...Read more

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What's the impact on the immune system after a pancreas transplant?

What's the impact on the immune system after a pancreas transplant?

Toned down: 1st of all, the quality of life and overall health of most pancreatic transplant patients are dramatically better than their pre transplant state. That being said, unless you have a perfect match, immuno suppressants are needed for you to live with the transplanted organ. Your immunity will not be optimal but should be manageable if you take proper precautioins. ...Read more

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Dr. John Landi
3 doctors shared insights

Transplant (Definition)

In medicine: a transfer from one body or body part to another of an organ (liver, heart, lung, kidney, pancreas bowel) or tissue (hand, face, hair). The immune system fights foreign invaders (like infections) so it will reject transplants from other people (allotransplants) because they look like infections. So transplants usually require drugs to ...Read more


Dr. L. Collins
3 doctors shared insights

Pancreas (Definition)

Abdominal organ. It is digestive organ: it secretes enzymes into the small bowel which break down food and help its absorption. It is also an endocrine organ: it produces hormones involved in sugar control and control of digestion. Insulin is one of these hormones. Diabetics either lack Insulin (type 1 diabetes) or have inadequate ...Read more