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Doctor insights on: Palpable Lump With Dcis

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True DCIS, TN, all dcis taken out at biopsy, lump showed nothing good margins. TN is scary Is it wise to have rads or go for MX. Chance TN comes back?

True DCIS, TN, all dcis taken out at biopsy, lump showed nothing good margins. TN is scary Is it wise to have rads or go for MX. Chance TN comes back?

AbbreviationsR dange: What is TN???? I could guess but I am sure to be wrong. Is TN stand for Tumor necrosis or Triple Negative or something else? Please help and in future avoid using Abbreviations, otherwise you will waste your and my time. ...Read more

Dr. Brad Goldenberg
56 Doctors shared insights

Intraductal Carcinoma (Definition)

Intraductal carcinoma is a noninvasive condition in which abnormal cells are found in the lining of a breast duct. The abnormal cells have not spread outside the duct to other ...Read more


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I'm post menopause 53ywith 1.5 cm lump in area of indentation, biopsy this mon. Sister had bilateral dcis at 39. What's my chance?

I'm post menopause 53ywith 1.5 cm lump in area of indentation, biopsy this mon. Sister had bilateral dcis at 39. What's my chance?

Biopsy needed R/O Ca: Be certain biopsy done in precise manner by surgeon and make sure report is definitely conclusive and accurate as biopsy at marginal area may miss diagnosis ending misdiagnosis as you are in high risk group. Wonder your sister had a genetic study done? Good luck ...Read more

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I have dcis and a new lump on the left breast. The surgeon just felt it, and said it's from a rib? Does that make sense?

I have dcis and a new lump on the left breast. The surgeon just felt it, and said it's from a rib? Does that make sense?

Catilage?: Your surgeon may be referring to the cartilage adjacent to the rib (costochondral junction). This would be near the breast, but not in the breast. If you feel a lump in your breast, though, please get a second opinion. ...Read more

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What does extensive low grade DCIS, No invasive malignancy is presented means in histopathology report for left breast lump with Benign fibrocycstic?

What does extensive low grade DCIS, No invasive malignancy is presented means in histopathology report for left breast lump with Benign fibrocycstic?

It means precancer: DCIS is a common problem in women. It is the beginning of cell changes which appear cancerous yet they are still not fully converted into cancer. Invasion by cancer cells is required in order to label them as cancerous. There is some risk that DCIS can convert into Invasive Breast Cancer. So it is a good idea to remove this abnormality/lump compeltely ...Read more

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How do you determine or detect dcis with palpable mass?

How do you determine or detect dcis with palpable mass?

Biopsy: A needle biopsy may be performed under local anesthesia in an office setting without much pain. Dcis can only be diagnosed by direct tissue examination. ...Read more

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How can I tell if I have dcis?

Cannot: Lcis and dcis are both conditions are variants of changes in the breast that can only be determined by biopsy. ...Read more

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How is lcis is different from dcis?

Risk factor v cancer: Dcis is a pre-cancerous condition that, if left untreated, could turn into a cancer. It is often detected by mammography. Lcis is not pre-cancerous, however, women who are found to have lcis are at an increased risk of developing breast cancer (in either breast). It is usually not detectable by mammography and is often found incidentally at the time of biopsy. ...Read more

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What are the treatment options for treating dcis?

What are the treatment options for treating dcis?

Depends: Dcis can have a wide range of presentations and therefore has a wide range of treatment options - every case is different. Some cases may be observed or treated with surgery alone; more often, surgery followed by radiation therapy and possibly anti-estrogen therapy may be needed. Dcis may be very widespread throughout the breast, and mastectomy may be required. ...Read more

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What is the definition or description of: intraductal carcinoma?

What is the definition or description of: intraductal carcinoma?

Noninvasive: Intraductal carcinoma is a noninvasive condition in which abnormal cells are found in the lining of a breast duct. The abnormal cells have not spread outside the duct to other tissues in the breast. ...Read more

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How fast does dcis spread?

Quite slowly: It is difficult to define. But it does not spread all that fast. You have a few months before you need to worry about that. ...Read more

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Why does dcis become invasive?

Unknown: If we knew the answer to this question, women with dcis would not all need surgery! about 50% of dcis (ductal carcinoma in situ), if left untreated, will go on to become invasive cancer. Certain genes in the dcis cells get "turned on", making them invasive, but we don't know what makes this switch happen. ...Read more

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Are there different types of dcis?

Yes: Dcis may be classified into different types based upon the pattern of growth when viewed under a microscope. These include comedo, papillary, cribiform, and solid. The comedo form tends to have the highest potential for becoming invasive if left untreated. Dcis may also be classified by how rapidly the cancer cells are dividing; this is referred to as the grade of the cancer. ...Read more

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How does dcis become harmfully invasive?

Unknown: If we knew the answer to this question, women with dcis would not all need surgery! about 50% of dcis (ductal carcinoma in situ), if left untreated, will go on to become invasive cancer. Certain genes in the dcis cells get "turned on", making them invasive, but we don't know what makes this switch happen. ...Read more

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Can you tell me what hg-dcis stands for?

High-grade DCIS: This designation refers to high-grade ductal carcinoma in situ. The adhesion molecules cd31 and cd44 are increasing expressed in very malignant breast ca. Such expression correlates well with tumor cells spreading within the ductal system of said breast. ...Read more

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How is dcis typically detected and diagnosed?

How is dcis typically detected and diagnosed?

Biopsy: Ductal carcinoma in situ (dcis) is initially seen on mammogram as a cluster of abnormal microscopic calcifications in the breast. A biopsy is then done to obtain a sample of the area of breast tissue in question. When the biopsy tissue is examined under a microscope it will definitively diagnose the dcis cells. ...Read more

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Does taking tamoxifen really benefit dcis?

Yes, for ER+ DCIS: The addition of tamoxifen to surgery and radiation therapy for dcis significantly reduced the risk of invasive cancer on the same beast by 40 % and risk for in situ breast cancer on the other breast by 60 percent. ...Read more

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My mum just been told that she has dcis, can I get a test to see if am going to get it?

My mum just been told that she has dcis, can I get a test to see if am going to get it?

No such test: Ductal carcinoma in situ is very common and usually quite manageable. And if there was such a test, what would you do? Have both your breasts amputated? That would be so wrong. Most women who die of breast cancer have lesions that could have been spotted and cured with the usual surveillance. I'm still a proponent of self-exam, and of course report any new dominant mass right away. Best wishes. ...Read more

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Cea. 5.6 but thought to be elevated due to ovarien cysts, recheck 5 weeks after surgery, its now 7.7, have history of dcis 4 years ago?

Cea. 5.6 but thought to be elevated due to ovarien cysts, recheck 5 weeks after surgery, its now 7.7, have history of dcis 4 years ago?

May still be normal: CEA cant be used for dx but only for monitoring the presence of a known malignancy with normal levels occassionaly reaching 10ugms. A normal value of CEA is a range from 0 to 2.5 (mcg/L). For a smoker, expected levels of CEA range from 0 to 5.0 (mcg/L). High levels may be an indication of cancer, but some will test high, even though they do not have cancer. ...Read more

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High grade DCIS 1mm removed successfully, pathology showed no spread, what chance of reoccurrence and what prognosis or need for follow up treatment?

High grade DCIS 1mm removed successfully, pathology showed no spread, what chance of reoccurrence and what prognosis or need for follow up treatment?

It depends on 3 fact: WE need to know the size of the DCIS, age of patient and recommendations of the doctor who has done surgery. There are 2 options of treatment once the tumor has been excised compeltely. Radiotherapy to the breast is commonly done in yourger (<60year olds) but can be spared in those over 75 year. Tamoxifen is another options proven to reduce the risk of recurrence. This is a curable condtion in 98% ...Read more

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Is radiation treatment necessary or required for dcis?

Is radiation treatment necessary or required for dcis?

Sometimes.: The primary treatment for dcis is surgical: either a lumpectomy or a mastectomy. Following a lumpectomy, radiation therapy is often recommended, depending on the type of dcis, the size, and the age of the patient. ...Read more

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What causes dcis breast cancer?

What causes dcis breast cancer?

In one word unknown: Ductal carcinoma in situ dcis is simply the sleeping cancer cells inside the breast ducts, like a garden hose loaded with cancer cells safe if they are inside the duct, once they are out side then is invasive cancer, ready to spread, cause is unknown at this time, from genetic mutations, braca I & ii age, hormonal uses. Environment, late age pregnancy life style etc are all attributed. ...Read more

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Are there any natural treatments for intraductal carcinoma?

Are there any natural treatments for intraductal carcinoma?

Yes BUT: There is debate about stage 0 breast cancer and how diff it is now vs how we found it 10-20 yrs ago. Some say smaller, low grade lesions shouldn't be called "cancer". Hi grade dcis certainly has risk of invasion over time. There are complementary treatments offered. Fam history & risk reduction should be considered. Tough to find cohort of pts w/ grade 2-3 dcis for whom radiation not beneficial. ...Read more

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Why is it that some women have to have mastectomy for dcis if it's a non invasive cancer?

You are right: Ordinarily, mastectomy is not necessary for precisely the reasons you have mentioned. So the standard treatment is excision of the dcis followed by radiotherapy to the affected breast. The only exception may be, if there are multiple dcis lesions in one breast....So unless you have this type of dcis, you do not need a mastectomy. ...Read more

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I am getting a diagnosis of dcis then a bilateral mastectomy preformed, what follow up treatment is good or needed?

No further treatment: If you had a bilateral mastectomy for DCIS, no further treatment is necessary. If you have a lumpectomy you will need radiation afterwards and 5 years of tamoxifen if the DCIS is estrogen receptor positive and if there is no contraindication to taking tamoxifen. ...Read more

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Approx. How long would it take for dcis to spread to the lymph nodes? I have heard it is a fairly slow growing cancer.

It varies: When it's found, 1 case in 100 has metastasized. There must have been a few cells that got through the basement membrane that the pathologist didn't find -- or the primary may have regressed. But don't mess around with a dcis diagnosis. Choose the option that is right for you -- and you'll be offered a choice. ...Read more

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Should tamoxifen be stopped if it caused endometrium thickening? Taking it for dcis, will it lead to endometrium cancer if continued?

Should tamoxifen be stopped if it caused endometrium thickening? Taking it for dcis, will it lead to endometrium cancer if continued?

Probably not: In a female in their 20's the discovery of dcis is unusual and raises possibility of the need for prevention of other breast disease with tamoxifen
furthermore endometrium cancer is very unusual in a women on tamoxifen of this age and particularly if she still has periods
most doctors if concerned by thickening will do a biopsy and resolve the concern. ...Read more