Doctor insights on:
Depends on stage: Chemotherapy is never used for stage 1 cancers (early). It is sometimes used in stage 2 cancers (early but more advanced than stage 1). Chemotherapy is definitely beneficial in stage 3 cancers (locally advanced) and in stage 4 cancers (distant spread). ...Read moreSee 2 more doctor answers
Stage 2B IDC breast cancer, her2+/ER/PR+Neoadjuvant taxol, (paclitaxel)A/C,lumpectomy,rads, lymphovascular invasion. What does this mean for prognosis & follow up?
Prognosis fair: Stage IIb breast cancer is usually palpable at 2-5 cm. and at time of procedure to remove lesion, sentinel nodes are + suggesting axillary dissection and reason for neoadjuvant therapy. Lymphovascular invasion increases chance for recurrence. With Her2+ Herceptin (trastuzumab) with chemo should be used and PET/CAT needed to assure met foci not missed in distal organs. Carful follow up needed. ...Read more
Yes?: As a rule, stage 4 cancer of the pancreas is incurable. As to being terminal, it depends on the definition. If you mean it will kill the patient at some point, the vast majority of the times the answer is yes. If you mean it will kill the patient right away, it depends on the situation. Never say never, though, some patients have surprised me in the past. Sorry if it is about you or a loved one. ...Read more
Depends: Some cancers are curable with today's chemotherapy even if they have spread extensively. Others (for example, the common lung cancers) may someday be curable when they have reached stage iv, but not today. I've just seen reports of possible cures of stage IV colon and stomach cancers; i'm hopeful. ...Read more
Extend/relieve: Mainly when chemotherapy is being recommended; it is for two purposes; either called curative when the goal is to achieve cure and then palliative; when the goal is mainly to improve quality of life by controlling the cancer in turn which is causing symptoms and hopefully to increase the period of time a person can live comfortably;. ...Read more
GB cancer is: Uncommon, so few studies done prospectively. Looking at results in people treated empirically, perhaps one person in 10 will respond. That needs to be balanced against side effects that tend to occur in most. Frank discussion about symptom rrelief focus rather than "shrink tumor" at all cost. ...Read moreSee 1 more doctor answer
Stage 3 nsclc right lung and lymph nodes. Chemo did not work, surgery impossible. Having 13 sessions palliative radiotherapy. What is life expectancy?
So many variables: Too many variables to give you a pertinent answer. Consult your oncologist to help you with clinical decisions ...Read more
Yes: If a 2b lesion has been completely resected with a lobectomy and there is no problem 6 months post surgery the best approach is for careful follow up. Adjuvant radiation for this stage of disease has shown no survival benefit and adjuvant chemo if initiated following surgery has only shown a 5% improvement in survival. ...Read more
Help means that: It can relieve a symptom, and restore better function...Brain and spinal cord are key, but any bone, or mass causing pain or obstruction can be "palliated" with short courses. However, it is not necessary to use the beam on every bone scan abnormality if it is not causing a symptom. ...Read moreSee 2 more doctor answers
Yes: It improves survival significantly in stage 1-3 lung cancers. Cyberknife provides survival similar to surgery in stage 1 patients. For stage 2-3 patients, both chemo and radiation may be used to improve survival. In certain patients with stage 4 cancer (such as with spread to the brain) radiation may help improve survival. ...Read moreSee 2 more doctor answers
Hepatocellular carcinoma.All spleen and partial liver resection.Later,secondary systemic cancer metastasis.any targeted therapy or immunotherapy?
Yes, for both: Hepatocellular Carcinoma is commonly treated with Sorafenib which is a type of targeted therapy. This is a good choice of treatment in case you have not yet received this drug. Immunotherapy using PD-1 inhibitors has also shown some modest evidence of benefit although it is not yet FDA approved for this indication. Ask your oncologist to guide your treatment further. ...Read more
Liver and peritoneal mets for mcrc patient . What is approx survival
With chemo , oxyplatin and raltitrexed ?
We can not guess: We can not tell you what the approx. survival as we do not have all the information to make a comment on the approx. survival You should discuss with your treating Oncologist There are second and third line treatments as well which may change the course ...Read more
Pancreatic cancer, ampullary tumor. Whipple procedure. Spread to liver, not respectable. Chemo for 6 months and continuing. Prognosis?
Poor: While Whipple is the best approach for a primary pancreatic or ampullary lesion, the recurrence rate at 1-2 yrs is 90%. Chemo either of the FOLFIERI or Genciabine /Abraxane combo have limited effects on liver mets which in pancreas are not considered amenable to resection. There is an FDA protocol using specific monoclonals targeting pancreas that might be available but only after chemo failure ...Read more