Doctor insights on:
Pagets Disease Myelofibrosis
I have myelofibrosis. How does the disease progress? Does your marrow just keep becoming scar tissue that can't produce blood? Is bone pain common?
Is myelofibrosis a terminal disease? Does it just keep progressing until all bone marrow is replaced by scar tissue that can't produce blood?
Nipple changes: Paget's disease of the breast is a type of cancer that involves the nipple and/or the dark tissue around the nipple (areloa). Often there is another tumor within the breast. Symptoms involve the nipple and include crusting, thickening, itching, scabbing or bleeding. There are many non-cancerous reasons for nipple symptoms, but if you have changes that don't resolve, see your health provider! ...Read moreSee 1 more doctor answer
Yes: Because paget's disease can be hereditary, some experts recommend that the brothers, sisters, and children of people with paget's disease talk to their doctor about having an alkaline phosphatase blood test every 2 to 3 years after age 40. Paget's disease is rare in people under 40. ...Read moreSee 1 more doctor answer
Around 1%: Paget's disease of the bone (and i assume you bone, not nipple) in about 1% of cases gives rise to aggressive cancers. Let's hope this does not happen to you. A few patients with paget's died as a result of high-output heart failure from the arteries connecting directly with veins in the bone; hopefully with today's treatment this will not happen. Good luck. ...Read moreSee 1 more doctor answer
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