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Doctor insights on: Pagets Disease Myelofibrosis

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Is myelofibrosis a terminal disease? Does it just keep progressing until all bone marrow is replaced by scar tissue that can't produce blood?

Is myelofibrosis a terminal disease? Does it just keep progressing until all bone marrow is replaced by scar tissue that can't produce blood?

Progressive: Yes, you described it well. New treatments are becoming available all the time, and they could extend your life! get treated! ...Read more

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Could mastectomy is the only option of treatment for paget"s disease?

Could mastectomy is the only option of treatment for paget"s disease?

For best results: Unfortunately it is diffuse diseases , it involves nipple and areola complex , when this area is removed will be cosmetically unacceptable , and is a aggressive disease are the reasons for mastectomy , although wide resection with good margins possible along with chemo-radiation is possible . It is also easier to reconstruct breast after mastectomy , if needed take a second opinion., discuss. ...Read more

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Is paget's disease common?

Is paget's disease common?

1-2% of population: Paget's disease of bone affects 1-2% of the population over 50 years of age. It is inherited in about 20% of patients. ...Read more

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What are the symptoms of Paget's disease?

What are the symptoms of Paget's disease?

Bone pain: Some people who have paget's disease will have absolutely no symptoms. Others may experience symptoms that are confused with arthritis. Others may have bone pain not in the joints. ...Read more

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Is paget's disease fatal?

Is paget's disease fatal?

Which?: Paget's disease of bone is a relatively benign and self-limited condition which can sometimes cause pain and in the worst case, deformity or fragility. But paget's disease of the breast is often a manifestation of an underlying breast cancer, which can certainly be fatal if untreated. ...Read more

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Is paget's disease treatable?

Is paget's disease treatable?

Yes: Paget's disease is very treatable. I have several paget's patients who do very well on yearly Reclast (zoledronic acid) infusions. ...Read more

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Can paget's disease be contagious?

Can paget's disease be contagious?

No: Some evidence suggests a virus might be involved in the cause but it still is not contagious. ...Read more

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