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Doctor insights on: Paget's Disease Of Bone

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How can Paget's disease of bone be treated?

How can Paget's disease of bone be treated?

See details: Mild cases may not require treatment. For the patients needing treatment, many of the meds used to treat osteoporosis will also treat pagets. I generally use Reclast (zoledronic acid) but there are other choices. ...Read more

Bone (Definition)

Bone is a living growing tissue made mostly of collagen (protein that provides soft framework) & the mineral calcium phosphate that adds strength & hardens the framework. Two types of bone are found in the body; cortical (dense compact outer layer) & trabecular (makes up inner layer, ...Read more


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What are the symptoms of paget's disease of bone?

What are the symptoms of paget's disease of bone?

Not very much to: Start.Most people who have paget's disease of bone experience no symptoms. When symptoms do occur, the most common complaint is bone pain. Pelvis. Paget's disease of bone in the pelvis can cause hip pain.Skull. An overgrowth of bone in the skull can cause hearing loss or headaches. And others see the link below. ...Read more

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What's your opinion on treating paget's disease of bone?

What's your opinion on treating paget's disease of bone?

Depends: Paget's can be localized or widespread. It can cause deformity and nerve damage.. Treatment involves drugs like Didronel (etidronate) etc..See a good doctor and have your xrays assessed fully. ...Read more

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What is the definition or description of: Paget's disease of bone?

What is the definition or description of: Paget's disease of bone?

See below: Paget's disease is a condition in which the normal turnover and remodeling of bone is disrupted. This results in dense, sometimes brittle and sclerotic bone to form that can cause both bone pain and fragility. ...Read more

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What are the cellular and molecular aspects of Paget's disease of bone ?

What are the cellular and molecular aspects of Paget's disease of bone ?

The answer: is too extensive for 400 words or less, but try this link: http://www.orthochirurg.com/resources/journals/JAAOS/Volume3/V3N6A4.pdf ...Read more

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Paget's disease of bone is a type of cancer?

Paget's disease of bone is a type of cancer?

No : Paget's disease is a disorder of abnormal bone remodeling. We all lose and build none everyday. In paget's, there's more building than losing, but in an abnormal structure, which makes the bone unstable and prone to breaking. There is often a lot of blood flow to the areas involved and so it can be red and hot. ...Read more

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Dr. Liawaty Ho Dr. Ho
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Are there alternative therapies for paget's disease of bone?

Dr. Liawaty Ho Dr. Ho
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PDOB: Bisphoshonates many times are used for pagets disease of the bones if it is symptomatic- pain etc, and /or if elevation of alkaline phosphatase/or serum calcium. It can relieve the pain and hopefully slow down the rapid turn over of the bone. ...Read more

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What endocrine gland does paget's disease of bone harm?

What endocrine gland does paget's disease of bone harm?

None: While called an endocrine disorder, to my knowledge, there is no specific organ/gland damage. Any pathologist can to weigh in? ...Read more

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Paget's disease of bone have anything to do with the breast?

Pagets disease : Pagets disease of the bone has nothing to do with pagets disease of the breast. ...Read more

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Relation of Paget disease of bone and giant cell tumor is what?

Giant: Cell tumor is a rare complication of paget's disease of bone. ...Read more

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What is paget's disease of the bone like?

What is paget's disease of the bone like?

Bone disorder: Paget' disease is a localized disorder of bone remodeling that involves excessive bone resorption, followed by increased bone formation. This overactivity followed by compensatory bone cell activity leads to a structurally disorganized mass of bone (woven bone), which is weaker, larger, more vascular, and more susceptible to fracture. It can be seen on x-rays, and can be a cause for bone pain. ...Read more

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In a nutshell, what is paget's disease of the bone?

Benign usually: Bone enlarges, can be painful, rarely can lead to malignancy. ...Read more

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What is the % of getting Paget's disease of the bone if there is a family history and have symptoms that could fit?

What is the % of getting Paget's disease of the bone if there is a family history and have symptoms that could fit?

Cannot estimate: No one even knows what percentage of older folks actually have some paget's lesions, since the disease is usually subclinical. If older folks with an unexplained elevation of alkaline phosphatase are assumed to have paget's, it's maybe 10%. The key is that paget's can be managed nowadays and of course it's largely hereditary. Let your physician know of the family history. ...Read more

Dr. Heidi Fowler
68 doctors shared insights

Bone (Definition)

Bone is a living growing tissue made mostly of collagen (protein that provides soft framework) & the mineral calcium phosphate that adds strength & hardens the framework. Two types of bone are found in the body; cortical (dense compact outer layer) & trabecular (makes up inner layer, ...Read more


Dr. Michael Thompson
562 doctors shared insights

Bone Diseases (Definition)

Any disease process that affects the skeletal system. Some can be metabolic, such as osteoporosis; others can be infectious, ...Read more