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Doctor insights on: Paget's Disease Of Bone

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What is paget's disease of the bone like?

What is paget's disease of the bone like?

Bone disorder: Paget' disease is a localized disorder of bone remodeling that involves excessive bone resorption, followed by increased bone formation. This overactivity followed by compensatory bone cell activity leads to a structurally disorganized mass of bone (woven bone), which is weaker, larger, more vascular, and more susceptible to fracture. It can be seen on x-rays, and can be a cause for bone pain. ...Read more

Bone (Definition)

Bone is a living growing tissue made mostly of collagen (protein that provides soft framework) & the mineral calcium phosphate that adds strength & hardens the framework. Two types of bone are found in the body; cortical (dense compact outer layer) & trabecular (makes up inner layer, ...Read more


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Paget's disease of bone is a type of cancer?

Paget's disease of bone is a type of cancer?

No : Paget's disease is a disorder of abnormal bone remodeling. We all lose and build none everyday. In paget's, there's more building than losing, but in an abnormal structure, which makes the bone unstable and prone to breaking. There is often a lot of blood flow to the areas involved and so it can be red and hot. ...Read more

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Relation of Paget disease of bone and giant cell tumor is what?

Relation of Paget disease of bone and giant cell tumor is what?

Giant: Cell tumor is a rare complication of paget's disease of bone. ...Read more

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Is paget's disease of breast curable?

Is paget's disease of breast curable?

It may be: Like other types of breast cancer with prompt and appropriate treatment there is a good likelihood that paget's disease can be successfully treated. ...Read more

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What is Paget disease of the nipple?

What is Paget disease of the nipple?

Cancer: Paget's disease of the breast is a scaly eczema-like skin change usually near or on the nipple, which is a malignant disease and is often associated with an underlying breast cancer. ...Read more

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Crohn's disease & metabolic bone disease. Is there a relation?

Crohn's disease & metabolic bone disease. Is there a relation?

Yes: Yes, potentially by three mechanisms: first, a percentage of patients with Crohn's disease will have an inflammatory arthritic component to it that can affect the bones; second, patients with Crohn's can have malabsorption of some of the key nutrients that make bone string; and third, some of the medications used to treat Crohn's can impact bone health. Discuss with your doctor. ...Read more

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What endocrine gland does paget's disease of bone harm?

What endocrine gland does paget's disease of bone harm?

None: While called an endocrine disorder, to my knowledge, there is no specific organ/gland damage. Any pathologist can to weigh in? ...Read more

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In a nutshell, what is paget's disease of the bone?

Benign usually: Bone enlarges, can be painful, rarely can lead to malignancy. ...Read more

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Dr. Liawaty Ho Dr. Ho
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Is there a cure for osteoporosis coupled with Paget's deasease of the bone?

Dr. Liawaty Ho Dr. Ho
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Is there a cure for osteoporosis coupled with Paget's deasease of the bone?

Unfortunately no: There is no cure for osteoporosis and no cure for paget's disease of the bone. Osteoporosis is part of the aging process, wear and tear- no we have not found any fountain of youth yet. Medication is available to help osteoporosis and paget's disease of the bone- that is intended to help relief bony pain, and for other indication- ie. Abnormal blood test etc. Please discuss w/ your md in detail. ...Read more

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What is brittle bone disease called?

OI: Osteogenesis imperfecta. There are several types of the disease. Type 1 is mild disease. Type iii is the one in which people are most affected. Hope this helps. ...Read more

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Is Paget's disease in the breast?

Is Paget's disease in the breast?

Yes and no: Pagets disease refers to an osseous lesion where there is over growth of bone and an extensive exophytic lesion can develop especially in the H&N area. Pagets of the breast is a disease of the very terminal milk duct system spilling out into the nipple and areola complex to present as a skin lesion. ...Read more

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What sort of disease is creutzfeldt-jacob disease (c.J.D.)?

What sort of disease is creutzfeldt-jacob disease (c.J.D.)?

A prion disease: Cjd is caused by infection/exposure to an abnormal form of the prion protein (pp). The abnormal form of pp is a completely bent out of shape version of the normal pp . This abnormal shape is very hard for the protein to change to spontaneously, but this can happen (1 in a million people). Once changed the abnormal pp changes other pp's and so on as the disease rapidly spreads/kills the brain. ...Read more

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Metabolic bone disease v. Osteoporosis, what's the difference?

Same thing: Osteoporosis is a metabolic bone disease. There are many other metabolic bone diseases. Metabolic bone disease is a catagory of disease. ...Read more

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Is paget's disease cancerous in all cases?

Is paget's disease cancerous in all cases?

In Situ or Invasive: Paget's dz represents less than 5% of all breast cancers; cancer cells are found involving the skin of the nipple, resembling eczema.Over 95% of the time an underlying cancer is found elsewhere in the breast, more commonly in-situ rather than invasive. Traditional rx was mastectomy however central lumpectomy (removal of nipple and areola) followed by radiation therapy is an acceptable alternative. ...Read more

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What are the symptoms of paget's disease of bone?

What are the symptoms of paget's disease of bone?

Not very much to: Start.Most people who have paget's disease of bone experience no symptoms. When symptoms do occur, the most common complaint is bone pain. Pelvis. Paget's disease of bone in the pelvis can cause hip pain.Skull. An overgrowth of bone in the skull can cause hearing loss or headaches. And others see the link below. ...Read more

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Is osteogenesis imperfecta a bone disease and disorder?

Is osteogenesis imperfecta a bone disease and disorder?

Yes: Osteogenesis imperfecta, or oi for short, is caused by genetic mutations of certain collagen genes. There are a number of types, and the severity can range from lethal shortly after birth to quite mild. Bone fractures, sometimes dental problems, and sometimes hearing loss can occur. The oi foundation is a great source of information: http://www.Oif.Org/site/pageserver. ...Read more

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What sort of disease is charcot-marie-tooth disease?

What sort of disease is charcot-marie-tooth disease?

Neuropathy: Charcot-marie-tooth (cmt) comes in a few different types. They are genetic disorders that affect function of peripheral nerves and are known as hereditary motor and sensory neuropathies (hsmn). They are slowly progressive diseases that often start in the 1st or 2nd decade and have progressive sensory and muscle function in the legs (starting at the feet) and progress upward, affecting arms too. ...Read more

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What is the relationship between gout disese and Paget's disease?

What is the relationship between gout disese and Paget's disease?

Unknown: It is currently not known definitively if there us a correlation, but i found this abstract regarding a study that might indicate association of the two at: http://www.Ncbi.Nlm.Nih.Gov/pubmed/3778075" rel="nofollow" target="_blank">http://www.Ncbi.Nlm.Nih.Gov/pubmed/3778075 i hope it helps. ...Read more

Dr. Romanth Waghmarae
40 doctors shared insights

Bone (Definition)

Bone is a living growing tissue made mostly of collagen (protein that provides soft framework) & the mineral calcium phosphate that adds strength & hardens the framework. Two types of bone are found in the body; cortical (dense compact outer layer) & trabecular (makes up inner layer, ...Read more


Dr. Michael Thompson
558 doctors shared insights

Bone Diseases (Definition)

Any disease process that affects the skeletal system. Some can be metabolic, such as osteoporosis; others can be infectious, ...Read more