Doctor insights on:
Paclitaxel Allergy In Children
Taxol (paclitaxel): TAXOL (paclitaxel) is contraindicated in patients who have a history of hypersensitivity reactions to TAXOL (paclitaxel) or other drugs formulated in Cremophor® EL (polyoxyethylated castor oil). TAXOL (paclitaxel) should not be used in patients with solid tumors who have baseline neutrophil counts of ...Read more
Allergies occur when your immune system is triggered by envirionmental factors it should ignore--for example, pollen in the air, or dander on a cat or dog--and creates cells to fight against them. An allergic reaction typically causes itching, congestion, or drainage, and ...Read more
Discontinued: Taxol (paclitaxel) has been discontinued in the us. There was originally concern because of the environmental impact of its original sourcing, no longer used, from the pacific yew. In addition, the assignment of rights, and even the name itself, to bristol-myers squibb were the subject of public debate and congressional hearings. ...Read more
Stops cell division.: In order to grow and spread, cancer cells need to divide and make copies of themselves. In order to divide and make copies of itself, the cell must prepare by organizing a kind of internal scaffolding, called microtubules. Taxol (paclitaxel) works by preventing the microtubules from functioning properly. Consequently, the cells can't divide properly and cancer growth is slowed. ...Read more
Taxol (paclitaxel) or Paclitaxel is a chemotheaputic drug which is used to treat a variety of cancers including lung, breast, ovarian and head and neck cancers.
It works by interfering with cell division.
It is produced by a fungus that lives in a south american tree bark. ...Read more
No: Taxol (paclitaxel) is a chemotherapeutic agent used to treat malignant, metastatic disease. Pneumonitis is an inflammatory process that needs antibiotics to bring the disease under control. One of the complications of chemo like Taxol (paclitaxel) is suppressing the immune system. As such reports appear that pneumonitis following the use of Taxol (paclitaxel) as in breast cancer occurs following the use of this agent. ...Read more
Kills cancer cells!: Taxol (paclitaxel) works by preventing cancer cells from reproducing themselves. In the picture you can see green "microtubules" that are pulling a cancer cell apart into two daughter cells. Taxol blocks microtubules, preventing them from being able to pull the cancer cell into two daughter cells. The cancer cell gets stuck trying to divide, and it dies. Taxol works for many cancer types. ...Read more
Yes, it can: Diarrhea is one of the common side effects of paclitaxel. While common, it’s recommended that you contact your healthcare team if you have more than 4 - 6 episodes in a 24 hour period (unless your healthcare team gave you different instructions). ...Read more
According to the package insert, the following are possible side effects of Taxol (paclitaxel) to the skin:
1) yellowing or darkening of the skin
2) severe redness or swelling, severe irritation, a hard lump, or skin changes where the injection was given
3) easy bruising or red pinpoint spots under your skin
4) pale skin
5) temporary hair loss
6) numbness, tingling, or burning
7) nail changes. ...Read more
Yes: Yes, it does.Get a more detailed answer ›
YES: Should only be used under the direction of an oncologist ...Read more
Chemotoxicity: ABRAXANE is an Injectable suspension of paclitaxel, a derivative of Taxol formulated as albumin-bound nanoparticles with a mean particle size of approximately 130 nanometers and sodium acetyltryptophanate. Toxicity of taxol and abraxane are similar and present with numbness, tingling, pain, or weakness in hands or feet; Sudden chest pain or discomfort, wheezing dry cough, Low WBC and fever. ...Read more
Paclitaxel: Paclitaxel or Taxol (paclitaxel) is a micro tubule inhibitor. It has great activity in breast cancer. Side effects include low blood counts, hair loss, numbness and tingling which may persist despite stopping the drug. Typically given either weekly or every other week in breast cancer. It is mixed with a chemical called cremophor which can cause an allergic reaction so patients are monitored. ...Read more
I was treated for 3 months (weekly) with paclitaxel. My tumor marker values increased while on the chemo. What should be next step?
Not too many:
Taxol (paclitaxel) is contraindicated in patients who have a history of hypersensitivity reactions to Taxol (paclitaxel) or other drugs made in cremophor el (polyoxyethylated castor oil).
Taxol (paclitaxel) also should not be used in patients with solid tumors who have white counts of less than 1500 cells/mm3 or in patients with aids-related kaposi’s sarcoma with baseline white counts of less than 1000 cells/mm3. ...Read more
Taxol (paclitaxel): Taxol (paclitaxel) has many potential side effects. See: http://www. Drugs. Com/sfx/taxol-side-effects. Html ...Read more
Medication: Taxol pain is usually though of a pain due to damage of the nerves (tingling/numbness/burning/electrical) also called neuropathic pain. Medications such as Lyrica (pregabalin) and Gabapentin have been shown to be of benefit. Narcotic medications may help somewhat but historically have been considered of little benefit. Speak with your physician. ...Read more
Taxol (paclitaxel): ...Works in cellular organelles called microtubules, which are the structures that separate the chromosomes during cell division. Taxol (paclitaxel) stabilizes the tubules and interrupts the normal cellular division process. ...Read more
Multiple, see below.: The most common adverse reactions are low blood counts, irritation of your nerve endings, nausea, vomiting, muscle & joint aches, diarrhea, irritation of your oral cavity, fever, swelling, and abnormalities of your liver function tests. See your doctor if you have any of these symptoms to see if your dose needs to be modified. ...Read more
Not really: Abraxane is a derivative of Taxol. It is employed after recurrent or metastatic pancreas cancers have failed Gemzar (gemcitabine) adding about 8 wks to the overall survival in these patients. The drug, protein-bound paclitaxel is an injectable formulation of paclitaxel, It has almost the same extent of neuropathy. ...Read more
2-3 days: It typically starts on day 3 and lasts for 2 or 3 days. Usually lasts for 3 days. Hope this helps. ...Read more
My friend gets carboplatin and Taxol (paclitaxel) combined and longterm - are there side effects to this?
Drug from a tree: Taxol is a chemotherapy drug used commonly to treat breast cancer. It's generic name is paclitaxel. It is also used to treat ovarian, lung, prostate, bladder, melanoma, esophageal cancer and other solid tumor cancers. It is made fromthe pacific yew tree bark. It works by preventing the cancer cells from dividing and therefore stops their growth. ...Read more