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Doctor insights on: Paclitaxel Allergy In Children

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Who should not use Taxol (paclitaxel)?

Who should not use Taxol (paclitaxel)?

Taxol (paclitaxel): TAXOL (paclitaxel) is contraindicated in patients who have a history of hypersensitivity reactions to TAXOL (paclitaxel) or other drugs formulated in Cremophor® EL (polyoxyethylated castor oil). TAXOL (paclitaxel) should not be used in patients with solid tumors who have baseline neutrophil counts of ...Read more

Dr. John Chiu
2,630 Doctors shared insights

Allergies (Definition)

Allergies occur when your immune system is triggered by envirionmental factors it should ignore--for example, pollen in the air, or dander on a cat or dog--and creates cells to fight against them. An allergic reaction typically causes itching, congestion, or drainage, and ...Read more


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Who should avoid taking taxol (paclitaxel)?

Who should avoid taking taxol (paclitaxel)?

Discontinued: Taxol (paclitaxel) has been discontinued in the us. There was originally concern because of the environmental impact of its original sourcing, no longer used, from the pacific yew. In addition, the assignment of rights, and even the name itself, to bristol-myers squibb were the subject of public debate and congressional hearings. ...Read more

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What exactly does Taxol (paclitaxel) affect?

Stops cell division.: In order to grow and spread, cancer cells need to divide and make copies of themselves. In order to divide and make copies of itself, the cell must prepare by organizing a kind of internal scaffolding, called microtubules. Taxol (paclitaxel) works by preventing the microtubules from functioning properly. Consequently, the cells can't divide properly and cancer growth is slowed. ...Read more

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Does Taxol (paclitaxel) stabilize microtubules?

Taxol (paclitaxel): Yes. You can read about this "Insights into the mechanism of microtubule stabilization by Taxol" See: http://www. Pnas. Org/content/103/27/10166.full ...Read more

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What should I do if overdose taxol (paclitaxel)?

What should I do if overdose taxol (paclitaxel)?

Call your doctor: Seek emergency medical attention if you think you have received too much taxol (paclitaxel).

Overdose symptoms may include numbness or tingling, fever, chills, mouth sores, unusual bleeding or weakness, or any signs of infection. ...Read more

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What is the definition or description of: taxol (paclitaxel)?

Chemotherapy: Taxol (paclitaxel) or Paclitaxel is a chemotheaputic drug which is used to treat a variety of cancers including lung, breast, ovarian and head and neck cancers.
It works by interfering with cell division.
It is produced by a fungus that lives in a south american tree bark. ...Read more

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Taxol (paclitaxel) side effects

Taxol (paclitaxel) side effects

Many: The most common side effects are hair loss, lowered blood counts, neuropathy, leg pain, mouth sores, and severe allergic reaction due to the solvent used to dilute Taxol (paclitaxel) (called cremophor). ...Read more

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Can Taxol (paclitaxel) treat pneumonitis?

Can Taxol (paclitaxel) treat pneumonitis?

No: Taxol (paclitaxel) is a chemotherapeutic agent used to treat malignant, metastatic disease. Pneumonitis is an inflammatory process that needs antibiotics to bring the disease under control. One of the complications of chemo like Taxol (paclitaxel) is suppressing the immune system. As such reports appear that pneumonitis following the use of Taxol (paclitaxel) as in breast cancer occurs following the use of this agent. ...Read more

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What is the role of Taxol (paclitaxel) in chemotherapy?

What is the role of Taxol (paclitaxel) in chemotherapy?

Kills cancer cells!: Taxol (paclitaxel) works by preventing cancer cells from reproducing themselves. In the picture you can see green "microtubules" that are pulling a cancer cell apart into two daughter cells. Taxol blocks microtubules, preventing them from being able to pull the cancer cell into two daughter cells. The cancer cell gets stuck trying to divide, and it dies. Taxol works for many cancer types. ...Read more

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Can Taxol (paclitaxel) cause diarrhea?

Can Taxol (paclitaxel) cause diarrhea?

Yes, it can: Diarrhea is one of the common side effects of paclitaxel. While common, it’s recommended that you contact your healthcare team if you have more than 4 - 6 episodes in a 24 hour period (unless your healthcare team gave you different instructions). ...Read more

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How does Taxol (paclitaxel) treat cancer?

How does Taxol (paclitaxel) treat cancer?

Inhibits division: Taxol (paclitaxel) is a chemotherapy drug that inhibits microtubules. This ends up inhibiting cell replication thereby making it difficult for cancer cells to continue dividing. ...Read more

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How can Taxol (paclitaxel) against the cancer?

How can Taxol (paclitaxel) against the cancer?

Unclear question: Please tell us in more detail: what do you want to know about taxol (paclitaxel)? It is a chemotherapy drug which is very useful in treating several different cancers. ...Read more

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Do you loose your hair with taxol (paclitaxel)?

Do you loose your hair with taxol (paclitaxel)?

Yes: Taxol (paclitaxel) is a chemo drug. It will cause hair loss if given in sufficient doses. ...Read more

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How fast does hair grow after taxol (paclitaxel)?

How fast does hair grow after taxol (paclitaxel)?

Varies: Hair growth after hair loss due to chemotherapy is variable. In general if your hair grew fast prior to therapy it may return more quickly (months) then if you had slow growing hair or hair loss prior to therapy. ...Read more

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What are Taxol (paclitaxel) side effects to skin?

Numerous: According to the package insert, the following are possible side effects of Taxol (paclitaxel) to the skin:
1) yellowing or darkening of the skin
2) severe redness or swelling, severe irritation, a hard lump, or skin changes where the injection was given
3) easy bruising or red pinpoint spots under your skin
4) pale skin
5) temporary hair loss
6) numbness, tingling, or burning
7) nail changes. ...Read more

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Do you need a prescription for Taxol (paclitaxel)?

YES: Should only be used under the direction of an oncologist ...Read more

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What are the different side effects of Abraxane and Taxol (paclitaxel)?

Chemotoxicity: ABRAXANE is an Injectable suspension of paclitaxel, a derivative of Taxol formulated as albumin-bound nanoparticles with a mean particle size of approximately 130 nanometers and sodium acetyltryptophanate. Toxicity of taxol and abraxane are similar and present with numbness, tingling, pain, or weakness in hands or feet; Sudden chest pain or discomfort, wheezing dry cough, Low WBC and fever. ...Read more

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Can you tell me about breastcancer, chemotherapy and experiences with Taxol (paclitaxel)?

Paclitaxel: Paclitaxel or Taxol (paclitaxel) is a micro tubule inhibitor. It has great activity in breast cancer. Side effects include low blood counts, hair loss, numbness and tingling which may persist despite stopping the drug. Typically given either weekly or every other week in breast cancer. It is mixed with a chemical called cremophor which can cause an allergic reaction so patients are monitored. ...Read more

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I was treated for 3 months (weekly) with paclitaxel. My tumor marker values increased while on the chemo. What should be next step?

I was treated for 3 months (weekly) with paclitaxel. My tumor marker values increased while on the chemo. What should be next step?

Follow up CT scan: If your tumor markers continue to increase while on chemo, it may mean that the chemo is not working. Regardless, it has been 3 months on treatment, your doctor should order a follow up ct scan to re-evaluate your cancer. ...Read more

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What is the definition or description of: paclitaxel?

Chemotherapy drug: Paclitaxel is a type of chemotherapy drug in the class called taxanes. It works by interfering with cell division. Major complications are nerve damage, allergic reactions, and low blood counts. It is used with many cancers, including breast, lung and ovary. ...Read more

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What is Taxol (paclitaxel) typically used for?

What is Taxol (paclitaxel) typically used for?

Chemotherapy: Taxol (paclitaxel) is a very effective chemotherapeutic drug for the treatment of some forms of breast and ovarian cancer. ...Read more

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What exactly is the drug Taxol (paclitaxel) used for?

What exactly is the drug Taxol (paclitaxel) used for?

Chemotherapy: Taxol (paclitaxel) is a widely used chemotherapy drug for breast, lung, head/neck, esophageal cancers. ...Read more

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What are some contraindications of taxol (paclitaxel)?

Not too many: Taxol (paclitaxel) is contraindicated in patients who have a history of hypersensitivity reactions to Taxol (paclitaxel) or other drugs made in cremophor el (polyoxyethylated castor oil).

Taxol (paclitaxel) also should not be used in patients with solid tumors who have white counts of less than 1500 cells/mm3 or in patients with aids-related kaposi’s sarcoma with baseline white counts of less than 1000 cells/mm3. ...Read more

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What side effects are associated with Taxol (paclitaxel)?

Taxol (paclitaxel): Taxol (paclitaxel) has many potential side effects. See: http://www. Drugs. Com/sfx/taxol-side-effects. Html ...Read more

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What information is on the Taxol (paclitaxel) package insert?

Taxol (paclitaxel) Label info:: See: http://www. Accessdata.fda.gov/drugsatfda_docs/label/2011/020262s049lbl. Pdf

Get a more detailed answer ›
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What can you do to help with pain caused by taxol (paclitaxel)?

Medication: Taxol pain is usually though of a pain due to damage of the nerves (tingling/numbness/burning/electrical) also called neuropathic pain. Medications such as Lyrica (pregabalin) and Gabapentin have been shown to be of benefit. Narcotic medications may help somewhat but historically have been considered of little benefit. Speak with your physician. ...Read more

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How can Taxol (paclitaxel) affect cancer cells?

Taxol (paclitaxel): ...Works in cellular organelles called microtubules, which are the structures that separate the chromosomes during cell division. Taxol (paclitaxel) stabilizes the tubules and interrupts the normal cellular division process. ...Read more

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What are common adverse reactions of taxol (paclitaxel)?

What are common adverse reactions of taxol (paclitaxel)?

Multiple, see below.: The most common adverse reactions are low blood counts, irritation of your nerve endings, nausea, vomiting, muscle & joint aches, diarrhea, irritation of your oral cavity, fever, swelling, and abnormalities of your liver function tests. See your doctor if you have any of these symptoms to see if your dose needs to be modified. ...Read more

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Is Abraxane or Taxol (paclitaxel) better for neuropathy?

Is Abraxane or Taxol (paclitaxel) better for neuropathy?

Not really: Abraxane is a derivative of Taxol. It is employed after recurrent or metastatic pancreas cancers have failed Gemzar (gemcitabine) adding about 8 wks to the overall survival in these patients. The drug, protein-bound paclitaxel is an injectable formulation of paclitaxel, It has almost the same extent of neuropathy. ...Read more

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For how long does leg pain from Taxol (paclitaxel) last?

For how long does leg pain from Taxol (paclitaxel) last?

2-3 days: It typically starts on day 3 and lasts for 2 or 3 days. Usually lasts for 3 days. Hope this helps. ...Read more

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Can the chemotherapy drug paclitaxel causes everyone's hair to fall out?

Can the chemotherapy drug paclitaxel causes everyone's hair to fall out?

Most but not all: Hair loss is seen in 85% of patients receiving paclitaxel, so the answer is not all but most patients will have temporary alopecia. ...Read more

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I was wondering does the chemotherapy drug paclitaxel causes your hair to fall out?

Yet it does: Unfortunately Paclitaxel is harsh on your hair and usually causes complete or near complete baldness.But it is temporary. ...Read more

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My friend gets carboplatin and Taxol (paclitaxel) combined and longterm - are there side effects to this?

Carbo/taxol: It is a very common regimen for cancer for multiple type of cancers. Read this for more info:

carboplatin- http://www. Nlm. Nih. Gov/medlineplus/druginfo/meds/a695017.Html
paclitaxel:
http://www. Nlm. Nih. Gov/medlineplus/druginfo/meds/a607070.Html. ...Read more

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What is Taxol (paclitaxel) used for?

Taxol (paclitaxel): Taxol (paclitaxel) is an anti-cancer chemotherapy drug ...Read more

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What exactly is paclitaxel (onxol, taxol)?

Drug from a tree: Taxol is a chemotherapy drug used commonly to treat breast cancer. It's generic name is paclitaxel. It is also used to treat ovarian, lung, prostate, bladder, melanoma, esophageal cancer and other solid tumor cancers. It is made fromthe pacific yew tree bark. It works by preventing the cancer cells from dividing and therefore stops their growth. ...Read more

Dr. Thomas Krivak
988 Doctors shared insights

Paclitaxel (Definition)

Paclitaxel is a type of chemotherapy drug in the class called taxanes. It works by interfering with cell division. Major complications are nerve damage, allergic reactions, and low blood counts. It is used with many cancers, including ...Read more