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Doctor insights on: Oxymetazoline Hydrochloride Pregnancy

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What are the side effects of oxymetazoline hydrochloride?

What are the side effects of oxymetazoline hydrochloride?

Afrin (oxymetazoline): Hello. Oxymetazoline is the active ingredient in afrin nasal spray. If it is used beyond 5 days, it could cause rhinitis medicamentosa. This is a condition where your nose needs to continue to use the spray just to be able to breath in and out of your nose. This ingredient can also be linked to increased heart rate and blood pressure, insomnia and urinary incontinance. ...Read more

Dr. Shari Jackson
4 Doctors shared insights

Pregnancy (Definition)

When your due date arrives, you will be more than ready to have your baby! Most women deliver the baby somewhere between 37 and 42 weeks. According to the American College of Obstetricians and Gynecologists, only 5% of babies arrive on the exact due date. Approximately 7% of babies are not delivered by 42 weeks, and when that happens, it is referred to ...Read more


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Is afrin (oxymetazoline) safe in pregnancy?

Afrin (oxymetazoline) is FDA: Pregnancy category c. Thus it has not been established if it will cause harm to unborn child in humans. This should be discussed with your obstetrician/ physician to determine if benefits outweigh risks. ...Read more

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Ok to use afrin (oxymetazoline) in 3rd trimester of pregnancy?

Ok to use afrin (oxymetazoline) in 3rd trimester of pregnancy?

NO!: Do not use afrin or any other nasal decongestant (claritin-d, allegra-d) throughout pregnancy, as it can cause unsafe spikes in your blood pressure, stroke, placental abruption, or even fetal loss! Plain oral antihistamines (not -d), nasal saline spray may be used instead, as may nasal steroids with medical supervision. ...Read more

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Why is it bad to use a nasal spray with oxymetazoline hydrochloride nightly?

Why is it bad to use a nasal spray with oxymetazoline hydrochloride nightly?

Tachyphylaxis: Basically your nose will become desentized to the effect of the oxymetazoline. If you use beyond the recommend time (3-5 days), your nose will upregulate receptors for it and require more and more for the same effect. There are better options for nightly nasal stuffiness and simple in-office procedures can be a permanent solution for you - see your local ent. ...Read more

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Is it safe to take amedicine for sinus like afrin (oxymetazoline) in the 1st trimesters of pregnancy?

FDA Category C: This substance is rated category c for pregnant women. Which means it is not advised unless the benefit outweighs the risk. There have been very few reported problems, but no real studies have been done to establish safety. As a fellow sinus sufferer....I would not use it. I would do steam inhalations with menthol and consider seeing the doctor if symptoms last longer than 10 days. Good luck. ...Read more

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Can I use amoxicillin for chronic sinusitis? Become addicted to oxymetazoline hydrochloride, what shall I do. What is the best alternative?

Can I use amoxicillin for chronic sinusitis? Become addicted to oxymetazoline hydrochloride, what shall I do. What is the best alternative?

Afrin (oxymetazoline) addiction: Hello. Rhinitis medicamentosa is a condition where your nasal turbinates become dependent on the spray to breath. The best recommendation is to quit cold turkey. Use pseudofed as needed and increase your head when you sleep. Your nose will return to normal within a few days. If this doesn't work see your ENT doctor. ...Read more

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Is 0.025% oxymetazoline hydrochloride safe to give a 2 year old for a cold with congested nose?

Congestion: Not unless evaluated & recommended by Physician. May not be safe in young children. Suggest saline drops & gently auctioning w/ bulb & evaluation by Dr. ...Read more

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Is afrin safe to use for severe nasal congestion during third trimester of pregnancy? I am currently 33 weeks and a few days and need sleep! Thank you

Is afrin safe to use for severe nasal congestion during third trimester of pregnancy? I am currently 33 weeks and a few days and need sleep! Thank you

If your BP is NML: Afrin (oxymetazoline) contains a vasoconstrictor, which is to say that it constricts blood vessels. In women predisposed to this, especially in late pregnancy, it may cause a rise in your bp, that could make your doctor suspicious of developing preeclampsia.

In small amounts it should be safe, but I would suggest you try antihistamines (they sometimes help), and avoid the decongestants for the above reason. ...Read more

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Pioglitazone hydrochloride tablets ok in pregnancy?

Pioglitazone hydrochloride tablets ok in pregnancy?

Not known.: The safety of pioglitazone (actos) in pregnancy, lactation (breastfeeding) and people under 18 is not established. ...Read more

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Why is ritodrine hydrochloride prescribed during pregnancy?

Why is ritodrine hydrochloride prescribed during pregnancy?

Contractions: Ritodrine is a very potent medication that among other effects on a human's body stops uterine contractions. ...Read more

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I'm taking vominor taps 25 mg meclozine hydrochloride 50 mg pyridoxine hydrochloride To avoid vomiting is there any danger on my pregnancy?

I'm taking vominor taps 25 mg meclozine hydrochloride 50 mg pyridoxine hydrochloride To avoid vomiting is there any danger on my pregnancy?

Approved: We do not have this drug in the US but reading online the components are category B which indicates studies show it is safe for use ...Read more

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Is it safe to use fexofenadine hydrochloride, ciprofloxacin, and moxifloxacin if im suspecting pregnancy at v early stage. (last ovulation on 9th dec)?

Is it safe to use fexofenadine hydrochloride, ciprofloxacin, and moxifloxacin if im suspecting pregnancy at v early stage. (last ovulation on 9th dec)?

No: Fenofenadine is in category b. Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women. But the fluorinated quinolones have the potential to create problems with ligaments and tendons and are not recommended for use in pregnancy. ...Read more

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If Each 5 ml contains:50mg glyceryl guaiacolate, 50mgpotassium citrate, 1.5mg terbutaline sulphate, 14mg diphenhydramine hydrochloride. Safe for pregnancy?

If Each 5 ml contains:50mg glyceryl guaiacolate, 50mgpotassium citrate, 1.5mg terbutaline sulphate, 14mg diphenhydramine hydrochloride. Safe for pregnancy?

Depends: The most susceptible time for the fetus is during the 1st trimester. After that, most allergy medication or cough medications are likely safe. Diphenhydramine has been associated with a slightly higher risk to develop cleft palate when used in the 1st trimester although the incidence is still very low. ...Read more

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Should I use expired afrin (oxymetazoline)?

Recommend: Use within expiration date. If it has been used previously - would definitely recommend throwing it away. ...Read more

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Is there still oxymetazoline in dristan?

Yes in the spray: The spray form has oxymetazoline. The oral form does not. ...Read more

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Oxymetazoline nasal solution considered a antihistamine?

Oxymetazoline: No, Oxymetazoline is a decongestant. It temporarily helps with nasal congestion by constricting the local blood vessels and reducing swelling and congestion. If used more than 3 days, it can cause a rebound effect and worsen symptoms. Antihistamines are a separate class of medications. They block the effects histamine, which help reduce the watery eyes and runny nose. ...Read more

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Can afrin (oxymetazoline) cause eustachian tube problems?

Not usually: If anything afrin (oxymetazoline) helps to open the et opening making it easier on the ears during diving and descending on planes. It may make it too open in which case the ear may feel plugged and you can hear your voice and breathing (autophony). ...Read more

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Deviated septum should I get surgery or take afrin (oxymetazoline)?

Surgery is definitiv: If your car's front end is out of alignment do you get a new paint job or repair the alignment? The septum in the nose is there to help your 'heating coils' (nasal turbinates) to moisturize the air you breathe. If it's out of alignment it overworks one side of the nose over the other and chronic congestion develops...You're much better off and breathe much better with a septoplasty. ...Read more

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Is it possible for you to use afrin (oxymetazoline) after nose cauterization?

Yes: I routinely recommend Afrin for three days after nasal cautery. Also use saline for crusting, saline gel to coat the nasal musosa and no vigorous nose blowing. ...Read more

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Would it be recommended to to take afrin (oxymetazoline) with a perforated eardrum?

Yes: Afrin (oxymetazoline) in the nose won't go to your ear so that is definitely safe. Even if you got a little afrin (oxymetazoline) in your ear it should still be okay as it is used sometimes in ear surgeries if there is bleeding in the ear.
Remember not to use afrin (oxymetazoline) more that a few days as it has the potential to be "addicting". ...Read more

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Afrin (oxymetazoline) mix with equal part saline solution. Allows for long term use without overdosing. Healthy? Or cancer causing?

The problem with. .: With long-term use of afrin is the rebound effect in the nasal cavity and a potential for increasing blood pressure. Diluting it with saline is not a good long-term solution. There are some prescription nasal sprays that are safe to use for the long-term treatment of allergies and nonallergic nasal conditions. There is no association with the use of afrin and cancer. ...Read more

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I am flying for the first time, is it okay to take sudafed with afrin (oxymetazoline)? If so how soon should I use booth before the plane takes off and lands?

I am flying for the first time, is it okay to take sudafed with afrin (oxymetazoline)? If so how soon should I use booth before the plane takes off and lands?

No: Both medications are considered decongestants, so you only want to take one or the other, not both. If you take the sudafed, I would take it about 30 minutes prior to flying. If you use the afrin, (oxymetazoline) it tends to start working fairly quickly, so 5-10 minutes prior to flying should be adequate. ...Read more

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I'm 33years old. My nasals (oxymetazoline) get blocked every 3-4 hours every day I face dis problem since 12 years. I tried lots of treatments but no cures please advice?

I'm 33years old. My nasals (oxymetazoline) get blocked every 3-4 hours every day I face dis problem since 12 years. I tried lots of treatments but no cures please advice?

Decongestants: If you have been using over the counter decongestant medications to try and get relief, such as afrin, neosynephrine, Vicks 4 way, etc, you may now have something called rhinitis medicamentosa due to the repeated use of the topical decongestant medication. This causes rebound nasal congestion when the decongestant wears off which occurs quicker over time. See and ENT or allergist. ...Read more

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Used afrin (oxymetazoline) then noticed acrid-like sensation/smell and it won't go away/ been 4 days stuffed up/ had hard time sleeping so tried the afrin (oxymetazoline)

This: This is a very hard question to answer, as there's not much research in this area, but I've heard this before with people who use afrin or sudafed (an oral decongestant). My feeling is that these medications overly dry out the nose (and your mucous), so it sticks around and festers. The other potential mechanism would be that the spray is directly irritating the nerve endings responsible for smell. We saw this with zycam spray (which rendered some without any sense of smell at all).

I'd recommend that you use lots of nasal saline spray to work on getting the stuff out of your nose. ...Read more

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My nose is terribly stuffy. I've used afrin (oxymetazoline) and Vicks for the allotted time but I am miserable! Is there anything else I can do? How long is afrin (oxymetazoline) ok?

From the afrin (oxymetazoline): Afrin (oxymetazoline) is best used for three days followed by three day break, may repeat this cycle. Usually it takes a while to develop swelling from daily use but some can have severe continuing swelling after just a couple applications. Also need to make sure there isn't a sinusitis causing the blockage. Suggest sudafed, topical steroid sprays, saline rinse, and brief oral steroids. May need to see ent. ...Read more

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Can expired afrin (oxymetazoline) still be used?

Agree w Dr. Klein: Recommend that expired oxymetazoline not be used. After the episode that oxymetazoline has been used for passes – toss the container (to avoid contamination). ...Read more

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What can I do if I overdosed on afrin (oxymetazoline)?

What can I do if I overdosed on afrin (oxymetazoline)?

Cold turkey: Technically, you don't overdose on afrin, you become addicted to it due to the rebound swelling of your nasal membranes after using it for more than a few days. Your physician can prescribe a nasal spray that is not addicting and add a steroid tablet if severe. ...Read more

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Would oxymetazoline HCl show on tox screen?

Not sure: Unlikely if used in recommended amounts. Depends on how much is used. If much used can elevate blood pressure so it can get into the system. Could call poison control center and find out. ...Read more

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Is afrin (oxymetazoline) allergy ok for kids?

Afrin (oxymetazoline): Afrin should only be used for 2 to 3 days. Longer use can cause rebound nasal congestion due to down regulation of the number of Alpha receptors in the nasal tissue. Avoid using afrin in children under the age of 6. ...Read more

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Can a pregnant woman take afrin (oxymetazoline)?

Can a pregnant woman take afrin (oxymetazoline)?

Yes, but. . .: Taken in the third trimester, there appears to be no problem. There are adverse events reported sporadically after high dose/prolonged use, especially in the first two trimesters. My recommendation is use saline nasal spray. Works very well and all it is salt water. ...Read more

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What is the treatment for oxymetazoline overdose?

Steroids: The immediate cessation of the nasal spray and the use of oral steroid for several weeks may reverse this condition known as rhinitis medicamentosa. The main thing to do once this condition, hopefully is reversed, is to obtain a specific diagnosis such as nasal allergy or hypertrophy (enlargement) of the inferior turbinates. Surgery to reduce the size of the inferior turbinates may be curative. ...Read more

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Can I use afrin (oxymetazoline) and sudafed together?

Yes, but: I recommend that my patients use afrin for an absolute maximum of 5 days if indicated. Sudafed is ok to use at the same time, as long as you have no medical contraindications to using it (heart problems, high blood pressure, etc). See your doctor if your nasal congestion symptoms are not improved within 5 days of use of either medication. ...Read more

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What is the treatment for afrin (oxymetazoline) overdose?

What is the treatment for afrin (oxymetazoline) overdose?

Stop Afrin (oxymetazoline): First, stop afrin, then tapered steroids, and prescription nasal spray, oral decongestants if cardiac status allows, sometimes saline drops or spray. ...Read more

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Can problems with the nasals (oxymetazoline) cause bad breath?

Can problems with the nasals (oxymetazoline) cause bad breath?

Yes: Infected sinuses can cause bad breath, but also have tonsils checked and ask your dentist to make sure there are no infections in your mouth. ...Read more

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I have etd can you use both afrin (oxymetazoline) and Flonase together?

Yes: Afren is an antihistaminic and Flonase is a nasal steroid. Mechanism of action of both drugs is different so they don't interfere with each other.
While Flonase can be used for extended periods (2 weeks or more), afrin is not recommended to use more than 5-7 days because of risk of rebound phenomenon. ...Read more

Dr. Heidi Fowler
190 Doctors shared insights

Oxymetazoline (Definition)

Oxymetazoline is a nasal preparation which is a kind of ...Read more


Dr. Heidi Fowler
197 Doctors shared insights

Afrin (Definition)

Afrin is a nasal preparation which is a kind of ...Read more