Doctor insights on:
70 years male with stomach cancer metastasized to liver and bone, is this a good chemo drug combination (capecitabine+oxaliplatin+zoledronic acid)?
Chemo: If you can tolerate capecitabine, the regiment will be good for the type of cancer. Also, consider to check her2-neu receptor status of the cancer - as if her2-neu receptor is positive, Herceptin (trastuzumab) which is an inhibitor to the her2-neu receptor should be considered as one of treatment options. ...Read more
Eloxatin (oxaliplatin): "ELOXATIN (oxaliplatin) should not be administered to patients with a history of known allergy to ELOXATIN (oxaliplatin) or other platinum compounds." See: http://dailymed. Nlm. Nih. Gov/dailymed/drugInfo. Cfm? Setid=3c740b43-f396-4998-bc66-6964a21f7161 ...Read more
Eloxatin (oxaliplatin): Oxaliplatin.Get a more detailed answer ›
DNA replication: It forms dna adducts that block dna replication and transcription, resulting in cell death in actively dividing cells. It forms bulkier platinum-dna adducts that may be more difficult to repair. Journal of clinical oncology vol 20, no 7 (april 1), 2002. Hope this helps. ...Read more
Eloxatin (oxaliplatin): See: http://www. Drugs. Com/sfx/oxaliplatin-side-effects. HtmlGet a more detailed answer ›
Increased Neuropathy: Patients report severe weakness, numbness, and tingling/shocking sensations after minimal exposure to cold. In some cases, the effects are startling - they have been described as feeling like spasms in the throat. Some find that the side effects decrease after warming or massaging the area. However, cold exposure during treatments may having lasting nerve effects, up to 14 days after infusion. ...Read more
Eloxatin (oxaliplatin): Yes, Eloxatin (oxaliplatin) requires a prescription.Get a more detailed answer ›
YES: Yes, sounds right. Xeloda (capecitabine) is a 5-FU oral prodrug given with Oxaliplatin IV usually for colorectal cancer. This regimen is known as XELOX. ...Read more
Ask: Ask your oncologist about your options. Depending on the malignancy, oxaliplatin may be your best option even after having a reaction. An Allergist can help to evaluate the reaction, and depending on its nature, suggest an effective premedication regimen or even assist with a desensitization procedure (basically fooling the immune system into accepting the drug). ...Read more
Eloxatin (oxaliplatin): Eloxatin (oxaliplatin) is beneficial in the treatment of colon & rectal cancers. ...Read more
Would "4 life factor plus" or max international's products do any good on a 59 year old cancer patient? He's on chemo with eloxatin (oxaliplatin) and capecitabina.
SORRY (:- (- NO: Unfortunately no. "tranfer factor" is one of the current fads, just see who is selling these products, literally your neighbors or friends. From what I can gather this person has colon cancer. These two chemotherapy agents are appropriate in this setting. Stick to what we know works. ...Read more
Yes, absolutely: 5fu (fluorouracil) based chemotherapy is the standard chemotherapy in colon cancer. Combination of 5-FU and oxaliplatin is widely used and a standard regiment of chemotherapy in colorectal cancer. A big randoomized clinical trial in colon cancer (mosaic study) has demonstrated the overall survival benefit of using combination of 5fu (fluorouracil)/oxaliplatin in stage iii colon cancer and limited case of stage ii disease. ...Read more
Immunotherapy: If primary lesion present it is essential to be resected. If lesion already removed and oxaliplatin advocated as part of chemo, other option are Xelodac given orally or avastin (bevacizumab) as a monoclonal antibody. In addition there is Erbitux, an epidermal growth factor 1 inhibitor, radiation to the site of potential recurrence and newer monoclonals in FDA trials targeting tumor protein. ...Read more
What are typical side effects of liver cancer chemo therapy consisting of Gemcitabine + Oxaliplatin (GEMOX)?
Modest side effects: Gemcitabine is a well tolerated chemo drug. It can cause some decrease in blood counts, so monitor your CBC periodically (something your oncologist will discuss and do it for you). Oxaliplatin has some additional side Effects like nausea and neuropathy, yet these are manageable by any good oncologist. So I would advice you to proceed with chemo and wait to worry if you have any side effects. ...Read more
For a 59 year old stomach cancer patient, should leg pain be taken as a chemotherapy's side effect? Patient is on eloxatin (oxaliplatin) and capecitabina... Thanks.
Maybe related: You are having leg pain and wonder if it is related to chemotherapy drugs. It is important to relay your leg pain to your doctor. This could be related to electrolyte imbalance, blood clot, among other things. Your doctor will want to know what makes the pain get better and when you notice it, if it resolves on its own. There may be additional studies ordered to look for clots. ...Read more
What is the most effective treatment for neuropathy and swollen hands that is caused by oxiplaten (a chemo drug)?
Difficult to treat: There are 2 forms acute and chronic. There are mixed benefits from use of calcium and magnesium infusion in the acute situation. The drug venlafaxine, an antidepressant has had some benefit in both situations. There are other drugs like Amitriptyline and Gabapentin has been helpful in some cases. It is hard to treat. It may very slowly improve if the drug is stopped. ...Read more
My grandfather, 80 y/o stage 4 colon cancer has been put on: levoronin, eloxatin, avastin, (bevacizumab) 5-fo. Is this appropriate for his first round of chemo?
Should one on chemo (xeloda+eloxatin+zometa) take multivitamins, calcium, antioxidants, resveratrol, digestive enzymes, fish oils, curcumin etc?
70 years male, stomach cancer metastasized to liver&bone, on (xeloda+eloxatin+zometa), can or should he take antioxidants during chemo?
There is no benefit I am aware of with antioxidants helping chemotherapy.
There are theoretical reasons why antioxidants can impair chemotherapies ability to kill cancer cells. I would not take additional unproven supplements without a md approval or without being on a clinical trial to study it. Anti-oxidants have harmed people in randomized studies. The won't harm, might help mantra is out. ...Read more
There are none...: Even the strongest opiates only "take the edge off" for people in chronic pain. Meds are only one part of dealing with the pain. A useful tool, but pain is so necessary for survival that we are not "allowed" to monkey with it much. In acute pain, the transition from miserable to less miserable can be great. In chronic pain, it's just part of the plan. ...Read more
Sometimes: Sometimes they are. For the most part, expired drugs simply lose potency once past their expiration date. There are, however, some drugs that actually become harmful if taken after they expire. As such, it is best to throw out any medications you have after a year. ...Read more
ASPRIN: Actually no one has decided on 'safest'. Asprin has been around since before you were born and unless you take too much (yes, too much of anything isn't good) most people are okay with it. If the pain it too severe for asprin you need to know what causes it. Good diagnosis is called for. See the dr. ...Read more