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Doctor insights on: Oxaliplatin Allergy In Children

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Who should not use Eloxatin (oxaliplatin)?

Who should not use Eloxatin (oxaliplatin)?

Eloxatin (oxaliplatin): "ELOXATIN (oxaliplatin) should not be administered to patients with a history of known allergy to ELOXATIN (oxaliplatin) or other platinum compounds." See: http://dailymed. Nlm. Nih. Gov/dailymed/drugInfo. Cfm? Setid=3c740b43-f396-4998-bc66-6964a21f7161 ...Read more

Dr. John Chiu
2,638 Doctors shared insights

Allergies (Definition)

Allergies occur when your immune system is triggered by envirionmental factors it should ignore--for example, pollen in the air, or dander on a cat or dog--and creates cells to fight against them. An allergic reaction typically causes itching, congestion, or drainage, and ...Read more


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Oxaliplatin mechanism. How does it work?

Oxaliplatin mechanism. How does it work?

Platinum analog: Is a cancer medication that interferes with the growth of cancer cells and slows their growth and spread in the body.
It is a platinum derivative. It binds to dna forming cross-links which inhibit dna replication and transcription, resulting in cell death. ...Read more

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What to do if I had an allergic reaction to oxaliplatin chemo?

What to do if I had an allergic reaction to oxaliplatin chemo?

Ask: Ask your oncologist about your options. Depending on the malignancy, oxaliplatin may be your best option even after having a reaction. An Allergist can help to evaluate the reaction, and depending on its nature, suggest an effective premedication regimen or even assist with a desensitization procedure (basically fooling the immune system into accepting the drug). ...Read more

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Why do doctors refer to oxaliplatin as eloxatin?

Eloxatin (oxaliplatin): Eloxatin (oxaliplatin) (brand name) and Oxaliplatin (generic name). ...Read more

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My chemo is 5-FU and oxaliplatin, tablet for one and intrevenus for the other?

My chemo is 5-FU and oxaliplatin, tablet for one and intrevenus for the other?

YES: Yes, sounds right. Xeloda (capecitabine) is a 5-FU oral prodrug given with Oxaliplatin IV usually for colorectal cancer. This regimen is known as XELOX. ...Read more

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What is the oxaliplatin mechanism. How?

What is the oxaliplatin mechanism. How?

DNA replication: It forms dna adducts that block dna replication and transcription, resulting in cell death in actively dividing cells. It forms bulkier platinum-dna adducts that may be more difficult to repair. Journal of clinical oncology vol 20, no 7 (april 1), 2002. Hope this helps. ...Read more

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Why can't you have cold food or drinks when taking oxaliplatin?

Why can't you have cold food or drinks when taking oxaliplatin?

Increased Neuropathy: Patients report severe weakness, numbness, and tingling/shocking sensations after minimal exposure to cold. In some cases, the effects are startling - they have been described as feeling like spasms in the throat. Some find that the side effects decrease after warming or massaging the area. However, cold exposure during treatments may having lasting nerve effects, up to 14 days after infusion. ...Read more

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How effective are oxaliplatin injections (Eloxatin) for treating colon cancer?

How effective are oxaliplatin injections (Eloxatin) for treating colon cancer?

Eloxatin (oxaliplatin): Eloxatin (oxaliplatin) is beneficial in the treatment of colon & rectal cancers. ...Read more

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Would "4 life factor plus" or max international's products do any good on a 59 year old cancer patient? He's on chemo with eloxatin (oxaliplatin) and capecitabina.

Would "4 life factor plus" or max international's products do any good on a 59 year old cancer patient? He's on chemo with eloxatin (oxaliplatin) and capecitabina.

SORRY (:- (- NO: Unfortunately no. "tranfer factor" is one of the current fads, just see who is selling these products, literally your neighbors or friends. From what I can gather this person has colon cancer. These two chemotherapy agents are appropriate in this setting. Stick to what we know works. ...Read more

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Anyone using oxaliplatin and 5-FU for colon cancer?

Yes, absolutely: 5fu (fluorouracil) based chemotherapy is the standard chemotherapy in colon cancer. Combination of 5-FU and oxaliplatin is widely used and a standard regiment of chemotherapy in colorectal cancer. A big randoomized clinical trial in colon cancer (mosaic study) has demonstrated the overall survival benefit of using combination of 5fu (fluorouracil)/oxaliplatin in stage iii colon cancer and limited case of stage ii disease. ...Read more

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What are your treatment options for colon cancer (allergic reaction to oxaliplatin)?

What are your treatment options for colon cancer (allergic reaction to oxaliplatin)?

Immunotherapy: If primary lesion present it is essential to be resected. If lesion already removed and oxaliplatin advocated as part of chemo, other option are Xelodac given orally or avastin (bevacizumab) as a monoclonal antibody. In addition there is Erbitux, an epidermal growth factor 1 inhibitor, radiation to the site of potential recurrence and newer monoclonals in FDA trials targeting tumor protein. ...Read more

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What are typical side effects of liver cancer chemo therapy consisting of Gemcitabine + Oxaliplatin (GEMOX)?

What are typical side effects of liver cancer chemo therapy consisting of Gemcitabine + Oxaliplatin (GEMOX)?

Modest side effects: Gemcitabine is a well tolerated chemo drug. It can cause some decrease in blood counts, so monitor your CBC periodically (something your oncologist will discuss and do it for you). Oxaliplatin has some additional side Effects like nausea and neuropathy, yet these are manageable by any good oncologist. So I would advice you to proceed with chemo and wait to worry if you have any side effects. ...Read more

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For a 59 year old stomach cancer patient, should leg pain be taken as a chemotherapy's side effect? Patient is on eloxatin (oxaliplatin) and capecitabina... Thanks.

For a 59 year old stomach cancer patient, should leg pain be taken as a chemotherapy's side effect? Patient is on eloxatin (oxaliplatin) and capecitabina... Thanks.

Maybe related: You are having leg pain and wonder if it is related to chemotherapy drugs. It is important to relay your leg pain to your doctor. This could be related to electrolyte imbalance, blood clot, among other things. Your doctor will want to know what makes the pain get better and when you notice it, if it resolves on its own. There may be additional studies ordered to look for clots. ...Read more

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70 years male with stomach cancer metastasized to liver and bone, is this a good chemo drug combination (capecitabine+oxaliplatin+zoledronic acid)?

70 years male with stomach cancer metastasized to liver and bone, is this a good chemo drug combination (capecitabine+oxaliplatin+zoledronic acid)?

Chemo: If you can tolerate capecitabine, the regiment will be good for the type of cancer. Also, consider to check her2-neu receptor status of the cancer - as if her2-neu receptor is positive, Herceptin (trastuzumab) which is an inhibitor to the her2-neu receptor should be considered as one of treatment options. ...Read more

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Why do some children have allergies?

Why do some children have allergies?

Exposure + Genes: One needs both a genetic component and "exposure" to a said allergen to develop an allergy. There is a growing support over the past 20 years, that growing up in an environment which is "too clean" can also lead to development of allergies down the road. Either way, allergies are on the rise. ...Read more

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How are children tested for allergies?

How are children tested for allergies?

See below: They are tested the same as everyone else. They can have skin testing performed by an allergist, or blood work ordered by their primary care provider. ...Read more

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I have an allergy to nuts and I was wondering if my children would also be allergic?

I have an allergy to nuts and I was wondering if my children would also be allergic?

Nut allergy: Maybe. Your children may have inherited genes from you that make them more likely to develop an allergy, but they do not inherit a specific allergy to a food e.g. Nuts. The children have to be exposed to food proteins in the diet, before an allergy can develop. Once one develops an allergy then they are always allergic and need proper medical attention to prevent severe problems. ...Read more

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How do docs test children for indoor & outdoor allergies?

How do docs test children for indoor & outdoor allergies?

Allergy tests: There are several types of testing. Some involve certain types of blood tests. Another method is to do a series of skin tests done by pricking the skin and applying different allergens. Other tests are provocative tests that can involve challanging the patient with allergic materials. Testing should be done by doctors specializing in allergy to obtain the best results. ...Read more

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What testing is there for? Children and food allergies?

What testing is there for? Children and food allergies?

Skin & blood tests: Prick testing with allergenic extracts or fresh foods can help confirm allergy, as can blood tests for specific ige antibodies (rast-type tests). However, both types of testing can produce false positive results, and confirmation with food challenges may be needed. ...Read more

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Can a parents allergies be passed on to their children?

Can a parents allergies be passed on to their children?

Not exactly: The ability to react to certain proteins in an allergic way is passed on from parents to their children, but a specific allergy is not. So if a mom is allergic to pollen and the dad is allergic to fire ants, their child may develop allergies but it may be to a food instead. If 1 parent has allergies, the child is 50% likely to develop allergies, but it's a 75% chance if both parents are allergic. ...Read more

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What kind of allergy medicine is best for children under 3 years old, with bad allergy probelms?

What kind of allergy medicine is best for children under 3 years old, with bad allergy probelms?

Antihistamine: Zyrtec and Claritin (loratadine) are approved for age 6m and older. But speak with your doctor before giving this medication to your child. ...Read more

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Where can I find a statistic for the number of children who died from allergies causing anaphylaxis in the u.S.?

Where can I find a statistic for the number of children who died from allergies causing anaphylaxis in the u.S.?

Only overall numbers: The incidence of anaphylaxis in children is unknown. Estimates of anaphylactic deaths (from drugs, foods, insect stings, and latex) in the us are 0.002 percent annually (2 per 100, 000): 500 fatalities from penicillin anaphylaxis; 40 fatalities from bee stings; 125-150 from food anaphylaxis. ...Read more

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My husband has nut and fish allergies. I have 4 children, 2 without allergies should I get rest of kids tested before giving them these foods?

My husband has nut and fish allergies. I have 4 children, 2 without allergies should I get rest of kids tested before giving them these foods?

Food testing: Food allergies can be frightening but there is no reason to test the children if they have not had reactions. Always be cautious when introducing a new food to an allergic child. ...Read more

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I give my 17mnth old 1/2 teaspoon of children's zyrtec (cetirizine) for allergies but some days it's not enough. Can I increase the dose or try something differ t?

I give my 17mnth old 1/2 teaspoon of children's zyrtec (cetirizine) for allergies but some days it's not enough. Can I increase the dose or try something differ t?

Do not increase: A 17 month old should not have allergies to inhaled items like dust or pollen. Zyrtec (cetirizine) could cause drowsiness and I would avoid long term use of zyrtec (cetirizine) in your child. If your child has a runny or stuffy nose that is unresponsive to zyrtec (cetirizine) then see your doctor to make sure there isn't an infection brewing. ...Read more

Dr. Arnold Malerman
15 Doctors shared insights

Oxaliplatin (Definition)

Oxaliplatin ...Read more


Dr. Cornelius O'leary jr
11 Doctors shared insights

Eloxatin (Definition)

Eloxatin ...Read more