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Doctor insights on: Ovarian Suppression Ahead Of Chemotherapy

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Hormonal effects of chemotherapy for breast cancer?

Hormonal effects of chemotherapy for breast cancer?

Please clarify.: It is unclear from your question what you are asking. Most breast cancers are estrogen-sensitive and can be treated with anti-estrogen medication (tamoxifen, aromatase inhibitors). Many women who are peri menopausal when receiving traditional chemotherapy develop ovarian suppression from the chemo and effectively "go into" menopause. I hope this helps. ...Read more

Dr. Devon Webster
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Chemotherapy (Definition)

The term chemotherapy typically is used to describe using chemicals to treat ...Read more


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Does taking tamoxifen for breast cancer treatment induce development of cancer of the uterus?

Does taking tamoxifen for breast cancer treatment induce development of cancer of the uterus?

Yes: The chance is about 1% and treatment is hysterectomy. With such a low chance then tamoxifen is worth the risk. A gynecologist needs to keep track of the patient and any unusual bleeding evaluated. There are also other hormone alternatives with less risk. Check with your medical oncologist to see which drug is best for a particular patient. ...Read more

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Can taking tamoxifen for breast cancer treatment induce cancer of the uterus ?

Can taking tamoxifen for breast cancer treatment induce cancer of the uterus ?

Maybe: There is a slight increased risk of endometrial cancer of 1 in 500 chance reported. The benefits of tamoxifen in treatment of breast cancer is much higher than the risk of endometrial cancer. Ask your oncologist and ob-gyn how best to follow or watch for this potential risk. ...Read more

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Does bep course of chemotherapy treatment effect fertilty in women.

Does bep course of chemotherapy treatment effect fertilty in women.

Yes: Any chemotherapy, bep (bleomycin, Etoposide and platinum) inclusive, can cause infertility by destroying the ovaries. Most ovaries will stop functioning either temporarily or permanently during chemotherapy. Some data has suggested that a shot of Lupron (leuprolide) during chemo can protect the ovaries but the data is not conclusive about lupron (leuprolide). ...Read more

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Ciii ovarian cancer in 06, 1212, surgery and chemo paxitaxtel/carboplatin. In remission. Recurrence treated with tamoxifen, carboplatin alone, abraxan, then topotacan to no avail. Which chemo next?

Ciii  ovarian cancer in 06, 1212, surgery and chemo paxitaxtel/carboplatin.  In remission. Recurrence treated with tamoxifen, carboplatin alone, abraxan, then topotacan to no avail. Which chemo next?

Many options: Choosing chemo depends on many factors, so only your doctor can decide what might work for you. Drugs you haven't mentioned include altretamine, capecitabine, cytoxan, (cyclophosphamide) vinorelbine, ifosfamide, etoposide, and irinotecan. There are also several hormonal agents. And a clinical trial might be an option. Check out www.Cancer.Gov for more info. And good luck. ...Read more

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What are the chances of chemo drug temodar (temozolomide) causing cancer later?

What are the chances of chemo drug temodar (temozolomide) causing cancer later?

Low: Temodar (temozolomide) is a chemotherapy drug that is taken orally. It works by damaging dna in cancer cells. It can also damage dna in normal cells, and in humans there is a small risk of developing acute leukemia as a result of temodar (temozolomide) use. This can happen years after taking the drug. The risk is less than a 1 in 100 chance, and the potential benefit is much higher than the benefit for treating cancer! ...Read more

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Does taking tamoxifen for breast cancer treatment induce cancer of the womb?

Does taking tamoxifen for breast cancer treatment induce cancer of the womb?

Small risk: Tamoxifen is asociated with a small (less than 5%) risk of uterine cancers, women on tamoxifen require regular gynecologic checkups every 6-12 months and high-risk women may need ultrasound screeenings too. ...Read more

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Can male breast cancer reoccur in the thyroid after 8 years of mastectomy, radiotherapy and chemotherapy?

Can male breast cancer reoccur in the thyroid after 8 years of mastectomy, radiotherapy and chemotherapy?

Less likely: The thyroid would be an unusual spot for breast cancer to spread. More common sites would be bone, liver, lung and brain. But with cancer, anything is possible. If there is a nodule on the thyroid the best thing to do would be an ultrasound guided biopsy if it looks concerning. ...Read more

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Hormone replacement therapy. Estrogen alone increases risk of uterine cancer. Adding progesterone increases risk of breast cancer, but reduces risk of uterine cancer. What's the right balance?

Hormone replacement therapy. Estrogen alone increases risk of uterine cancer. Adding progesterone increases risk of breast cancer, but reduces risk of uterine cancer. What's the right balance?

Individual: Yes, estrogen alone does increase the risk of uterine cancer over time. And yes the whi showed that the combination of a certain synthetic estrogen and a certain synthetic progestin increased the risk of breast cancer. But most specialists do not use those older types of synthetic hormones and with newer medications the risks are lower and different. So a balance can be achieved. ...Read more

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Does taking tamoxifen for breast cancer treatment cause cancer of the uterus ?

Yes: Tamoxifen has been shown to increase the risk of uterine cancer, not unlike estrogen replacement therapy, with an incidence of ~1:500. However, this is almost-always caught at its earliest stage, with very high cure rates. If you compare the benefit of tamoxifen for either treating or preventing breast cancer compared to this risk, the benefit far outweighs the risk. ...Read more

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What are financial implications of using herceptin (trastuzumab) as a breast cancer treatment?

What are financial implications of using herceptin (trastuzumab) as a breast cancer treatment?

?: I have never had an issue of trastuzumab (herceptin) coverage in appropriate patients. Individual co-pays are based on each patients insurance. There may be a benefit of trastuzumab in 0/low expression breast cancer that is the subject of a cooperative group clinical trial -- nsabp b-47 - clinicaltrials.Gov id: nct01275677. ...Read more

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Is arimidex (anastrozole) when given as prevention of recurrence of breast cancer only used with estrogen receptive cancer?

Is arimidex (anastrozole) when given as prevention of recurrence of breast cancer only used with estrogen receptive cancer?

Yes*: Arimidex (anastrozole) belongs to a category of drugs called aromatase inhibitors. These are effective chemotherapeutic agents for people with either estrogen-sensitive or *progesterone-sensitive breast cancers. This is only effective after menopause; premenopausal women may use tamoxifen for a similar response rate. ...Read more

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What are side effects of radiation therapy for ovarian cancer?

What are side effects of radiation therapy for ovarian cancer?

See below: Radiation therapy is not commonly used in the initial management of ovarian cancer; the role of radiation therapy is typically limited to palliation of symptoms if the cancer has spread somewhere else and is causing pain or other localized problems. In this case, the side effects depend heavily on the organ being treated but typically are very manageable. ...Read more

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After completion of 6 cycles of chemo and mastectomy for early stage triple neg invasive carsinoma how to know there is no more cancer cells in body?

After completion of 6 cycles of chemo and  mastectomy for early stage triple neg invasive carsinoma how to know there is no more cancer cells in body?

Surveillance: Congratulations on completing this therapy. It sounds at this point like you have no evidence of cancer, so the hope going forward is that you will continue to show no evidence of recurrent disease. You can expect to be evaluated by a combination of physical examinations as well as potentially some routine imaging though this will depend on stage specifics. Congratulations again. ...Read more

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What are the side effects of chemo therapy with breast cancer?

What are the side effects of chemo therapy with breast cancer?

Several: Hair loss, nausea, fatigue, risk for infection. However, the incidence of nausea is a lot less now with newer medications. Hope this helps. ...Read more

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What are your thoughts of the use of tamoxifen for refractory ovarian cancer?

What are your thoughts of the use of tamoxifen for  refractory  ovarian cancer?

Little: Probably not very beneficial. For uterine cancer, there has been some data. Little if any benefit in ovarian cancer. Unlike breast cancer in which there is a benefit in estrogen positive disease because of the estrogen target, there is no target in ovarian cancer. Hope this helps. ...Read more

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Would male breast cancer reoccur in thyroid after 8 years of mastectomy, radiotherapy and chemotherapy?

Would male breast cancer reoccur in thyroid after 8 years of mastectomy, radiotherapy and chemotherapy?

Very unlikely: Very few cancers metastasize to the thyroid. I'll bet you it's a new tumor. The pathologist can tell for sure. ...Read more

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Wat are intraaxillary lymph nodes? what are the side effects of radiation for breast cancer..& how long its given for earlier stage of cancer

Wat are intraaxillary lymph nodes?
what are the side effects of radiation for breast cancer..& how long its given for earlier stage of cancer

Partial answer: The nodes in the armpit are often involved in patients with breast cancer and are generally treated with radiation to kill tumor cells. Radiation also damages other tissues needed for drainage of fluid from the arm. Due to that damage, some patients develop swelling of the arm on the involved side. You should discuss these issues with your doctor who knows your health status better. ...Read more

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What herbs kill ovarian cancer stage 3 c. Had hystetectomy and 6 rounds of chemo and there are still very small nodules?

What herbs kill ovarian cancer stage 3 c. Had hystetectomy and 6 rounds of chemo and there are still very small nodules?

No Standard: There are no standard guidelines nor adequate research to answer your question. However, dr. Keith block is a well known figure in the arena of integrative medicine in cancer care where you may find some answers. http://www.blockmd.com. ...Read more