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Doctor insights on: Ovarian Insufficiency In Children

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Dr. Michael Opsahl
28 Doctors shared insights

Ovarian Insufficiency (Definition)

"Primary ovarian insufficiency describes a spectrum of declining ovarian functions and reduced fecundity due premature decrease in follicle number, an increase in follicle destruction or poor response to gonadotropins".This abnormal "Hypoestrogenic state" increases risks of vasomotor symptoms, urogenital atrophy, osteoporosis, fractures, cardiovascular diseases and other ...Read more


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What are the symptoms of ovarian insufficiency?

What are the symptoms of ovarian insufficiency?

Irregular/ no period: Irregular cycles or no periods, especially in a woman who was regular before, is a common sign. However there are many other causes of irregular cycles that we need to exclude. Hot flashes, vaginal dryness, or mood changes may occur, particularly if the woman's periods are stopped. Some women with primary ovarian insufficiency still have regular periods but see md for difficulty getting pregnant. ...Read more

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What is the definition or description of: Ovarian insufficiency?

What is the definition or description of: Ovarian insufficiency?

Spectrum of disorder: "Primary ovarian insufficiency describes a spectrum of declining ovarian functions and reduced fecundity due premature decrease in follicle number, an increase in follicle destruction or poor response to gonadotropins".This abnormal "Hypoestrogenic state" increases risks of vasomotor symptoms, urogenital atrophy, osteoporosis, fractures, cardiovascular diseases and other issues if left untreated ...Read more

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What is the treatment for ovarian insufficiency?

What is the treatment for ovarian insufficiency?

Trying to conceive?: If not trying to conceive: bone density scan, calcium, vitamin d, and hormone replacement with estrogen and progestin. We look for and treat any adrenal insufficiency. If you're trying to conceive, 5-10% of women with poi will get pregnant on their own after diagnosis, but if you truly have poi we don't have good fertility treatments using your own eggs. Egg donation or embryo donation are best. ...Read more

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What are the tests for primary ovarian insufficiency?

What are the tests for primary ovarian insufficiency?

Many tests, see REI: Reproductive endocrinology md will confirm poi - pregnancy test, fsh, lh, estradiol, amh, thyroid and prolactin tests, pelvic ultrasound. Test for genetic causes: karyotype looking for turner's syndrome, fragile x premutation testing, fish test for sry (y-chromosome material). Test adrenal antibodies which cause addison's disease. Screen for diabetes, thyroid antibodies, and parathyroid disease. ...Read more

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What are the symptoms associated with primary ovarian insufficiency?

What are the symptoms associated with primary ovarian insufficiency?

Irregular/ no period: Irregular cycles or no periods, especially in a woman who was regular before, is a common sign. However there are many other causes of irregular cycles that we need to exclude. Hot flashes, vaginal dryness, or mood changes may occur, particularly if the woman's periods are stopped. Some women with primary ovarian insufficiency still have regular periods but see md for difficulty getting pregnant. ...Read more

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What is the definition or description of: Primary ovarian insufficiency?

What is the definition or description of: Primary ovarian insufficiency?

Early failure: Premature ovarian failure is a loss of normal function of your ovaries before age 40. If your ovaries fail, they don't produce normal amounts of the hormone estrogen or release eggs regularly. ...Read more

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Are there certain things that make getting primary ovarian insufficiency more likely?

Are there certain things that make getting primary ovarian insufficiency more likely?

Early ovarian failur: Chemotherapy, ovarian surgery, genetics, exposure to radiation would be the most common antecedants. ...Read more

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Was planning to see classmates at upcoming 20th reunion. Now I am hearing my best friend has ovarian insufficiency. What is that?

Premature menopause: Ovarian insufficiency is another way of saying someone is going through menopause. There can be various causes of why someone might go through this prematurely. This can be treated with supplemental hormones and should not keep your friend from attending the reunion. ...Read more

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What is the treatment for primary ovarian insufficiency?

What is the treatment for primary ovarian insufficiency?

Trying to conceive?: If not trying to conceive: bone density scan, calcium, vitamin d, and hormone replacement with estrogen and progestin. We look for and treat any adrenal insufficiency. If you're trying to conceive, 5-10% of women with poi will get pregnant on their own after diagnosis, but if you truly have poi we don't have good fertility treatments using your own eggs. Egg donation or embryo donation are best. ...Read more

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Is there something wrong with ovaries or hormone system if I have ovarian insufficiency?

Is there something wrong with ovaries or hormone system if I have ovarian insufficiency?

EARLY menopause: Ovarian failure or 'insufficiency' is a really another name for menopause (which may be premature if <40 yo). Normally the pituitary gland (in the brain) sends 2 hormone messengers FSH & lh to 'tell' the ovary to make estrogen/'female' hormones. When the ovary 'fails' =estrogen levels drop and fsh/lh levels rise confirming ovarian 'insufficiency'. Treatment with 'hormones' is optional. ...Read more

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Is it common for primary ovarian insufficiency to develop postpartum?

Is it common for primary ovarian insufficiency to develop postpartum?

Early menopause: Premature ovarian failure can occur at any age, but it is unusual immediately following pregnancy. Regular menses suggest ovulation and a healthy ovary, but there are many causes of lack of menses after having a baby. Included considerations are breastfeeding, polycystic ovaries (estrogen is produced, but no ovulation), another pregnancy! Pituitary failure (sheehan's syndrome) is a rare cause. ...Read more

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With primary ovarian insufficiency and not taking hrt, is it possible for a woman to get an occasional period?

With primary ovarian insufficiency and not taking hrt, is it possible for a woman to get an occasional period?

Kinda: If you have little to no estrogen from your ovaries you should not bleed at all. But if you have some in your diet or are overweight you may have bleeding so talk to your obgyn or endocrinologist. ...Read more

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Has anyone seen a patient with adrenal insufficiency, intermittent ovarian failure, intermittent glucose intolerance, and thyroid values in normal range? Perhaps also with a pituitary tumor?

Has anyone seen a patient with adrenal insufficiency, intermittent ovarian failure, intermittent glucose intolerance, and thyroid values in normal range? Perhaps also with a pituitary tumor?

Pituitary tumors: You need an endocrinologist to sort this out. A big pituitary tumor (>10 mm) can wipe out other hormones; you could lose some (eg reproductive) but not others. Typically the last to go from a pituitary insult is TSH and acth (thyroid and adrenal), but odd things can occur. A micro tumor does not usually damage the rest of the pituitary, but may produce excess hormone (eg. Prolactin, acth). ...Read more

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Can people with polysistic ovarian syndrome still have children?

Can people with polysistic ovarian syndrome still have children?

Absolutely, yes.: There are ways to increase your odds of ovulating despite pcos, either with lifestyle changes and/or medications. ...Read more

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Peripherally oriented ovarian follicles mean I can't have children?

Peripherally oriented ovarian follicles mean I can't have children?

No: This comment just locates the follicles in reference to the center of the ovary. Peripheral just means toward the outside, rather than a predominantly central or generalized pattern. ...Read more

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Got an ovarian cyst removed, can I still have children?

Got an ovarian cyst removed, can I still have children?

Many do: As long as you have one healthy ovary and tubes a pregnancy is possible. Removal of an ovarian cyst does not necessarily ruin the ovary it came from. ...Read more

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I have two children, one at 45, nursed, now 53, suddenly struck with ovarian discomfort and pressure, cramps? (celebate)

I have two children, one at 45, nursed, now 53, suddenly struck with ovarian discomfort and pressure, cramps? (celebate)

??????????????: As written your submission does not provide clear background information or ask a clear question. Please start over. Your submissions are not linked and the site docs cannot view uploaded information or prior questions. ...Read more

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How do I tell my children I have stage 4 ovarian cancer?

How do I tell my children I have stage 4 ovarian cancer?

Be honest.: It's important to be honest with them. Cancer is understandably a shocking and emotionally taxing thing for everyone involved, so keeping everyone on the same page will allow you and your loved ones to support each other through difficult times. Keep them, as well as yourself, informed of all the amazing resources out there to help patients and their families cope with their situation. ...Read more

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Does abortions cause ovarian cancer I had six abortions in between six live and healthy children?

Does abortions cause ovarian cancer I had six abortions in between six live and healthy children?

That's a lot: Six is a lot of abortions, but sometimes we have to abort and destroy a baby fetus in order to prevent giving birth to a baby with genetic mutations. One's body does not get a higher chance of ovarian or breast cancer from abortions. A woman has a lower chance of these cancers if she spends more of her life being pregnant and breastfeeding afterwards... so having six kids can be a good thing. ...Read more

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Bilaterally which is a nonspecific finding that can be associated with polycystic ovarian syndrome does this mean I can't have children?

Bilaterally which is a nonspecific finding that can be associated with polycystic ovarian syndrome does this mean I can't have children?

Bilateral what??: Bilateral just means both sides. It is not a diagnosis it is a location designation. Women with PCOS may have more difficulty attaining pregnancy but most will do so. ...Read more

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Should I screen my children for ovarian cancer genes since it seems to be so deadly? There is no history in my family.

Should I screen my children for ovarian cancer genes since it seems to be so deadly? There is no history in my family.

No: There is no simple screen for ovarian cancer susceptibility beyond the breast-ovarian cancer gene (brca) testing that costs $2600-3300. Only families with cases of ovarian or early onset (<45) breast cancer should consider this testing. ...Read more

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Hello I am 26 and have been TTC for 4 years. I have two children but can not get pregnant now. Please help! I did have ovarian cysts and have them scrapped. Could this have something to do with it?

Hello I am 26 and have been TTC for 4 years. I have two children but can not get pregnant now. Please help! I did have ovarian cysts and have them scrapped. Could this have something to do with it?

May be: So that is a long time and means that the chance of becoming pregnant on your own each month is very low. Not sure exactly what procedure you had but it would be very important to see a fertility specialist at this point. 4 years age age 26 is a big deal ...Read more

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I am at my wits end after suffering with painful ovarian cysts for years. What more can be done? I am a 24 y/o female who has suffered painful ovarian cysts for the past 4 years. I have two children, and suffered one miscarriage before they were born.

I am at my wits end after suffering with painful ovarian cysts for years. What more can be done? I am a 24 y/o female who has suffered painful ovarian cysts for the past 4 years. I have two children, and suffered one miscarriage before they were born.

I: I understand your frustration. It sounds like you have failed all conservative treatment. Please discuss surgical options with your physician. You may also want to seek out a second opinion about other conservative treatments. Cysts are very painful and debilitating and I'm sorry you are going through this. ...Read more

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I have a severe case of polycystic ovarian syndrome and im on bc pills, will I be able to get pregnant and have children?

I have a severe case of polycystic ovarian syndrome and im on bc pills, will I be able to get pregnant and have children?

Yes: Women with pcos, even severe, can conceive but they usually need the help of a fertility specialist or ob/gyn in order to induce ovulation and to exclude other reasons for infertility. After a certain age the biggest limitation for pregnancy becomes the age of the female as opposed to the lack of ovulation. ...Read more