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Doctor insights on: Ovarian Cancer Risk Hypothyroid Hormone Replacement Therapy

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Dr. Barry Rosen
4,357 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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Does hormone replacement therapy for menopausal symptoms cause breast cancer?

Does hormone replacement therapy for menopausal symptoms cause breast cancer?

Increases risk: Hormone replacement therapy (hrt) has been shown to increase one's risk for breast cancer if taken for longer than 5 years. The current recommendation is to take low doses for a limited amount of time and then stop. There are some other non hormonal medications that can be used to help manage menopausal symptoms. ...Read more

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Does hormone replacement therapy increase your chances for breast cancer expotentionally?

Does hormone replacement therapy increase your chances for breast cancer expotentionally?

Not exponentially: Data from the whi (women's health initiative) study show that estrogen alone does not significantly increase the risk of breast cancer, especially if started within 5 years of menopause. However, estrogen + Progesterone (needed when women still have a uterus to prevent uterine cancer) increases the risk of breast cancer to about 2x the baseline risk. Progesterone appears to be the "bad guy". ...Read more

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Still confused about estrogen, hormone replacement therapy and cardiovascular disease?

Still confused about estrogen, hormone replacement therapy and cardiovascular disease?

Complex issues: Female hormones increase thromboembolism, deep venous thrombosis--progesteron is blamed, more than estrogen--because at menopause, there is changes in blood coagulation?Increase weight, arteriosclerosis, metabolic syndrome all of this increase risk of cardiovascular disease-- estrogen can be given at low dose for brief periods. ...Read more

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Does postmenopausal hormone therapy lead to breast cancer?

Does postmenopausal hormone therapy lead to breast cancer?

Very low Risk: With due respect. The landmark study, whi, is called into question in so many ways. The nih spent millions to answer very little. As an re, i feel there are many facets to HRT and a careful and comprehensive evaluation of the literature supports a very minimal at best increase in breast cancer and the evidence points to the progestin component only (provera). Consultation warranted. ...Read more

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Hormone therapy for menopausal symptoms cause breast cancer?

Hormone therapy for menopausal symptoms cause breast cancer?

NO BUT INCREASE RISK: Hormone therapy does not cause breast cancer but it does increase your risk of breast cancer. According to the national nurses health study using hormone replacement therapy for 10-15 yrs increases risk about 20%, if used more than 15 yrs it doubles to around 40%. Talk to your doctor to help you decide how to better manage postmenopausal symptoms. ...Read more

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How safe is hormone replacement therapy if family history breast cancer?

How safe is hormone replacement therapy if family history breast cancer?

Varies: If a first order relative (mother, sister, daughter) has bc i would take ert only briefly and then only for severe symptoms. Remember that we try to prevent breast cancer by prescribing tamoxifen - which blocks estrogen. Adding ert definitely increases risk, somewhat, so you have to balance risks/benefits. Some women are miserable without it - and a short course may be appropriate for them. ...Read more

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Will taking hormone replacement therapy causes iatrogenic menstruation in menopaused women?

Will taking hormone replacement therapy causes iatrogenic menstruation in menopaused women?

Usually no: During the time a woman is perimenopausal hormonal manipulation can cause some spotting or bleeding depending on how the hormones are dosed. Once a woman is truly menopausal hrt does not usually cause menstruation. Vaginal bleeding in the post-menopausal woman is considered abnormal & worthy of investigation. ...Read more

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Could premerin homone replacement cause Paget breast cancer?

Could premerin homone replacement cause Paget breast cancer?

Unlikely: We think that combined hormone replacement including estrogen and Progesterone cause an increase in breast cancer of which paget's disease if the breast is a type. Premarin (conjugated estrogens) only contains estrogen. ...Read more

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Does hormone replacement therapy have significant risks?

Does hormone replacement therapy have significant risks?

It can: If not monitored. Estradiol and estriol levels are much higher in ovulating women & pregnant women, respectively. Birth control estrogen is 5x more potent than the estrogen used in hrt and carries risks of blood clots, heart attack etc. Estrone levels are high in overweight women who carry the same risks. Hrt that is not converted to estrone is the key, in my opinion. ...Read more

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Hormone replacement therapy. Estrogen alone increases risk of uterine cancer. Adding progesterone increases risk of breast cancer, but reduces risk of uterine cancer. What's the right balance?

Hormone replacement therapy. Estrogen alone increases risk of uterine cancer. Adding progesterone increases risk of breast cancer, but reduces risk of uterine cancer. What's the right balance?

Individual: Yes, estrogen alone does increase the risk of uterine cancer over time. And yes the whi showed that the combination of a certain synthetic estrogen and a certain synthetic progestin increased the risk of breast cancer. But most specialists do not use those older types of synthetic hormones and with newer medications the risks are lower and different. So a balance can be achieved. ...Read more

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Hormone therapy for prostate cancer?

Hormone therapy for prostate cancer?

Treatment: Hormone therapy consists of medications that decrease the effects of testosterone on prostate cancer and a man's body. Prostate cancer growth is primarily fueled by testosterone. If testosterone is absent/ineffective, prostate cancer hopefully would stop growing. Hormone therapy has several varieties including pills and injections. Given for advanced disease or at times prior to radiation. ...Read more

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Does hormone replacement therapy prevent osteoporosis?

Does hormone replacement therapy prevent osteoporosis?

Yes, an option: There are many things you can do to avoid osteoporosis. Things you can't change: your family history, race, aging. Things you can change: get adequate calcium: 1500 mg per day, vit d 2000 iu per day, physical activity: 150 minutes per week (or 50 jumps per day), have normal tsh, get regular screening, and know your personal risk factors. Have a frax score done to help you decide what to do. ...Read more

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Does hashimoto's thyroiditis increase your risk for thyroid cancer?

Does hashimoto's thyroiditis increase your risk for thyroid cancer?

A little: Is an association between hashimotos and thyroid lymphoma. If you had thyroidectomy, for other reasons, you don't need to worry about developing that. If not, intermittent neck ultrasounds can be a useful screening test. ...Read more

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How does hormone replacement therapy to treat menopause symptoms affect the risk of cancer?

How does hormone replacement therapy to treat menopause symptoms affect the risk of cancer?

Not likely: Hormone replacement therapy remains one of the most effective means of controlling and sometimes eliminating these symptoms. Our current thinking is that for healthy women in their 50s -- women who have not had breast cancer or a history of blood clots -- and have been experiencing the symptoms of menopause for less than 10 years, hormone therapy can be very effective for symptom relief. ...Read more

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Does hormone replacement therapy (hrt) increase a woman's risk for heart disease or not?

Does hormone replacement therapy (hrt) increase a woman's risk for heart disease or not?

Yes and no: It reduces the risk of developing plaque which reduces long term risk. However, it increases the risk of forming clots, especially in smokers, which is the final step leading to stroke or heart attack. ...Read more

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How much does hormone replacement therapy play in the development of ovarian cancer?

How much does hormone replacement therapy play in the development of ovarian cancer?

Probably none: There does not appear to be a correlation with hormone replacement therapy and ovarian cancer. Nevertheless, i always balance estrogen treatment with progesterone. There is some evidence that women estrogen dominance (overweight, infertile, polycystic ovaries and women who don't ovulate) have higher estrogen dependent cancers like breast, colon, uterine and ovarian. It's all about balance. ...Read more

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35 years, childless, hypothyroidism, 50 mcg Thyronorm daily. Read long term use of thyroid HRT can increase risk of breast cancer. Is this true?

35 years, childless, hypothyroidism, 50 mcg Thyronorm daily. Read long term use of thyroid HRT can increase risk of breast cancer. Is this true?

No: this medication is a synthetic Thyroid hormone which you need to survive. The levels should be monitored and adjusted by a doctor. It should not increase your Breast cancer risk. The replacement hormones people use for hot flushes (estrogen/progesterone) during and after menopause do cause increased risk. ...Read more

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On hormone replacement therapy since hysterectomy at age 31 for ovarian cancer- now 50. Do i need to end HRT for normal menopause age?

On hormone replacement therapy  since  hysterectomy at age 31 for ovarian cancer- now 50. Do i need to  end HRT  for normal menopause  age?

Add progesterone: Estrogen continues to be made from the fat cells and adrenal glands so you need to be on natural Progesterone forever to balance the estrogen. It stimulates the p53 gene to protect you from cancers. ...Read more

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Is there a link between ovarian cancer and hormone replacement therapy?

Is there a link between ovarian cancer and hormone replacement therapy?

No: Causes of ovarian cancer are poorly understood. In some cases, there is a hereditary risk. There is no evidence that hormone therapy affects ovarian cancer. There is evidence that use of birth control pills is protective against ovarian cancer. ...Read more

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Dr. Bryan Treacy
870 doctors shared insights

Hormone Replacement Therapy (Definition)

Usually done to provide the hormones that would be deficient upon surgical removal or inactivity or malfunction of a hormone producing gland or organ. The endocrinologist is the medical specialist that specializes amongst other things , in doing just that. Insulin/glucagon-pancreas, thyroid hormone-thyroid, ovaries, testicles, hypothalamus, ...Read more


Dr. Mark Pack
1 doctor shared a insight

Hormone (Definition)

A hormone (from greek ὁρμή, "impetus") is a chemical released by a cell or a gland in one part of the body that sends out messages that affect cells in other parts of the organism. Only a little amount of hormone is required to alter cell metabolism. In essence, it is a chemical messenger that transports a signal from ...Read more