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Doctor insights on: Ovarian Cancer Risk Hypothyroid Hormone Replacement Therapy

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How much does hormone replacement therapy play in the development of ovarian cancer?

How much does hormone replacement therapy play in the development of ovarian cancer?

Probably none: There does not appear to be a correlation with hormone replacement therapy and ovarian cancer. Nevertheless, i always balance estrogen treatment with progesterone. There is some evidence that women estrogen dominance (overweight, infertile, polycystic ovaries and women who don't ovulate) have higher estrogen dependent cancers like breast, colon, uterine and ovarian. It's all about balance. ...Read more

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Dr. Barry Rosen
4,224 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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Is there a link between ovarian cancer and hormone replacement therapy?

Is there a link between ovarian cancer and hormone replacement therapy?

No: Causes of ovarian cancer are poorly understood. In some cases, there is a hereditary risk. There is no evidence that hormone therapy affects ovarian cancer. There is evidence that use of birth control pills is protective against ovarian cancer. ...Read more

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On hormone replacement therapy since hysterectomy at age 31 for ovarian cancer- now 50. Do i need to end HRT for normal menopause age?

On hormone replacement therapy  since  hysterectomy at age 31 for ovarian cancer- now 50. Do i need to  end HRT  for normal menopause  age?

Add progesterone: Estrogen continues to be made from the fat cells and adrenal glands so you need to be on natural Progesterone forever to balance the estrogen. It stimulates the p53 gene to protect you from cancers. ...Read more

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Should women take hormone replacement therapy if they have a history of cancer?

Should women take hormone replacement therapy if they have a history of cancer?

Depends: Women with history of breast cancer may or may not be given the ok to take estrogen. Some endometrial cancer cases can take ht after @ cancer free yrs. Should not affect other cancers. Best to seek counsel with your md. ...Read more

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Does hormone replacement therapy increase your chances for breast cancer expotentionally?

Does hormone replacement therapy increase your chances for breast cancer expotentionally?

Not exponentially: Data from the whi (women's health initiative) study show that estrogen alone does not significantly increase the risk of breast cancer, especially if started within 5 years of menopause. However, estrogen + Progesterone (needed when women still have a uterus to prevent uterine cancer) increases the risk of breast cancer to about 2x the baseline risk. Progesterone appears to be the "bad guy". ...Read more

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How does hormone replacement therapy to treat menopause symptoms affect the risk of cancer?

How does hormone replacement therapy to treat menopause symptoms affect the risk of cancer?

Not likely: Hormone replacement therapy remains one of the most effective means of controlling and sometimes eliminating these symptoms. Our current thinking is that for healthy women in their 50s -- women who have not had breast cancer or a history of blood clots -- and have been experiencing the symptoms of menopause for less than 10 years, hormone therapy can be very effective for symptom relief. ...Read more

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How safe is hormone replacement therapy if family history breast cancer?

How safe is hormone replacement therapy if family history breast cancer?

Varies: If a first order relative (mother, sister, daughter) has bc i would take ert only briefly and then only for severe symptoms. Remember that we try to prevent breast cancer by prescribing tamoxifen - which blocks estrogen. Adding ert definitely increases risk, somewhat, so you have to balance risks/benefits. Some women are miserable without it - and a short course may be appropriate for them. ...Read more

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Does hormone replacement therapy for menopausal symptoms cause breast cancer?

Does hormone replacement therapy for menopausal symptoms cause breast cancer?

Increases risk: Hormone replacement therapy (hrt) has been shown to increase one's risk for breast cancer if taken for longer than 5 years. The current recommendation is to take low doses for a limited amount of time and then stop. There are some other non hormonal medications that can be used to help manage menopausal symptoms. ...Read more

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Hormone replacement therapy. Estrogen alone increases risk of uterine cancer. Adding progesterone increases risk of breast cancer, but reduces risk of uterine cancer. What's the right balance?

Hormone replacement therapy. Estrogen alone increases risk of uterine cancer. Adding progesterone increases risk of breast cancer, but reduces risk of uterine cancer. What's the right balance?

Individual: Yes, estrogen alone does increase the risk of uterine cancer over time. And yes the whi showed that the combination of a certain synthetic estrogen and a certain synthetic progestin increased the risk of breast cancer. But most specialists do not use those older types of synthetic hormones and with newer medications the risks are lower and different. So a balance can be achieved. ...Read more

Dr. Gurmukh Singh
481 doctors shared insights

Ovarian Cancer (Definition)

It is a cancer which arises from the ovary. This cancer is typically silent, producing little or no symptoms till it spreads, first into the pelvic area and later into the peritoneal cavity leading to fluid accumulation(ascites) which is often the first symptom. Despite its late presentation, there is a reasonable treatment for it, with some long term survivors even ...Read more


Dr. Su Fairchild
1,212 doctors shared insights

Hypothyroidism (Definition)

The thyroid gland is an endocrine organ located in the front part of the neck. Its role is to make thyroid hormones, which control the way cells use energy. Hyperthyroidism results when the thyroid gland is overactive and too much thyroid hormone is produced, which speeds up metabolism. This results in weight loss, a quick heartbeat, sweating, nervousness, ...Read more