Doctor insights on:
Ovarian Cancer And Essential Thrombocytosis
It is a neoplasm: Essential thrombocythemia (et) is part of group of myeloproliferative neoplasm (mpn) - is a clonal disorder. Mpns are predisposed to clonal evolution and disease transformation to myelodysplasia and/or acute leukemia. The propensity to transform into acute myeloid leukemia differs among the subgroups- being the highest for cml- greater than 90% if left untreated and et being the least - about 5%. ...Read moreSee 1 more doctor answer
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
The same cancer: Recurrence means that it's the same cancer that has come back. While it may come back in a different place in the abdomen-- the cell type is the same regardless even if the ovaries are no longer there. A biopsy will show if the recurrence is consistent with the original cancer. ...Read more
Pelvis & abomen: Commonly when advaced spreads in the abdomen affecting the peritoneum producing increased intra pelvic and abdominal fluid. As most cancers may spread to liver, lung, brain, bone. Most ovarian cancer produce symptoms only in advanced stages with nonspecific sensations of increased belly or intraabdominally discomfort. Ca 125 is not a screening test because of so many false positives and negatives. ...Read moreSee 1 more doctor answer
In some cases: In some cases of ovarian cancer, a mass (or masses) can be felt in the pelvis with a manual vaginal examination. In advanced cases, a swollen abdomen from ascites can be seen on exam (but this is not specific for ovarian cancer). In most cases of ovarian cancer, the findings on exam are quite nonspecific. ...Read more
Depends.: It is notoriously hard to detect early. Pelvic ultrasound and family history along with serum ca-125 are some approaches to early detection that have not been particularly effective. Current research is aiming at identifying a serum proteomic signature of early ovarian cancer that can be clinically useful. ...Read more
Not curable: Typically when someone refers to end stage they are describing a case that is not curable. Most of the time these are patients who have developed disease that has spread to parts of the body outside of where the cancer originally developed (i.e. Metastasis). ...Read moreSee 1 more doctor answer
Non specific: Symptoms of ovarian cancer are not specific. They often mimic other common conditions. These may include: abdominal pressure, fullness, swelling or bloating, pelvic discomfort or pain, persistent indigestion, gas or nausea, changes in bowel habits, such as constipation, changes in bladder habits, including a frequent need to urinate, loss of appetite or quickly feeling full, and low back pain. ...Read more
Not very likely: The actual answer to this depends on whether there is a family history of ovarian cancer. If a close family member of the 25 year old has had ovarian cancer then the family could carry the brca gene which would increase the possibility of ovarian cancer. Symptoms of ovarian cancer are generally bloating and possibly abdominal pain. An ultrasound of the ovaries will find cancer. ...Read more
None: Unfortunately, no screening test (be it ultrasound, physical exam, or ca 125 tumor marker) can detect ovarian cancer early enough to make a difference. People with high risk for cancer often choose to have the ovaries removed before they get malignant. If you have concerns about your risk, please have a chat with your doc. Best to you. ...Read more
None at first: Sadly, there is no screening for ovarian cancer and by the time it causes symptoms, it is often advanced. Abdominal swelling, pain, or shortness of breath can happen in those cases. If you have strong family history for breast or ovarian ca, ask your gyn about risk assessment and genetic counseling. If the risk is high enough, a woman may benefit of preventative surgery. ...Read moreSee 1 more doctor answer
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