Doctor insights on:
Outcome For Invasive Ductal And Invasive Lobular Ca
Probably no, but...: Most of the statistics I have seen show similar rates of lobular cancer in carriers of BRCA 1/2 mutations (which is the most common recognizable inherited breast cancer trait) compared to non-carriers. Exception: carriers of CDH1 mutations (hereditary diffuse gastric cancer syndrome) have high risk for aggressive stomach cancer and lobular breast cancer. ...Read moreSee 1 more doctor answer
No: Although both are breast cancers they are different in the significance attached to them. Lobular carcinoma is more likely to be larger, lymph node positive and estrogen positive then invasive ductal. A study in the ann surg oncol. 2010 jul;17(7):1862-9. Epub 2010 feb 17 suggests that invasive lobular carcinoma has a better prognosis stage for stage than invasive ductal carcinoma. ...Read more
Stage-Dependent: Breast cancers are staged based upon the size of the cancer, lymph node or distant organ involvement, direct extension to the skin or chest wall muscles, and unique molecular features of the tumor. Published rates of 5-yr survival (http://www.Cancer.Org/cancer/breastcancer/detailedguide/breast-cancer-survival-by-stage) vary quite a bit based on these variables, between 15%-93%. ...Read more
It depends on many f: Most women with localized breast cancer do very well and there is high cure rate. Overall 75%-80% of breast cancers are curable. But you need to know what stage of cancer it is? You should also know what subtype(there are 3 different types) of breast cancer it is. Further there is the matter of what type of adjuvant therapy(post surgery treatment) was used. I'am sure your oncologist can answeryr. ...Read moreSee 1 more doctor answer
Best treatment for invasive and in-situ carcinoma with lobular features, sbr grade 2, 8mm in size?
If this was a....: ...Exam question, i'd say: lumpectomy with sentinel node analysis followed by radiation or mastectomy with sentinel node. Either would be followed by 5-10 years of oral endocrine therapy (tamoxifen or ai) if the tumor is er or pr positive. There may be other factors i'm not aware of that may move a doc to take a different approach so have a good talk with your doc about your options. ...Read more
Pr ER and cerbb2 all negative stage 1b full mastectomy with recon size 0.8 CM invasive lobular casinoma in situ do not want chemo what's yr opinion?
Not usually needed: Breast cancer is very complicated and there are many variables, so hard to say in your particular case. But generally, lcis is usually considered a marker for increased risk of an invasive cancer in both breasts (at equal risk). Invasive lobular carcinoma is treated like "regular" or ductal carcinoma. Your post seems contradictory (it can't be both in situ and invasive). Would need more info. ...Read moreSee 1 more doctor answer
INVASIVE or DCIS?: These terms are incongruous: dcis is, by definition, breast cancer that has not "broken out" of the ducts and entered the adjacent supportive tissue of the breast; invasive, or infiltrating ductal cancer, by definition, has. The treatment of these 2 diseases is quite different since there is a risk of systemic disease with the latter. Please clarify, thanks. ...Read moreSee 3 more doctor answers
Depends: Not all breast cancers are the same and many other factors help to predict better or poorer outcomes such as tumor grade, # of positive lymph nodes, estrogen receptor status, her2neu status, etc. A score called oncotype DX based on genetic profiling of the cancer helps define prognosis also and tailor decisions as to the best and most beneficial treatment to use. ...Read more
More than 50%: This is a hard question. Invasive ductal carcinoma is the most common type of breast cancer. It depends on whether it's stage3a, b or c, and the time of survival. At 5 years after diagnosis, 50-60% of women with stage 3 breast cancer are alive. Other factors are age, receptor status of the tumor, number of lymph nodes involved, and treatment. Remember that survival is improving all the time! ...Read moreSee 1 more doctor answer
Depends: Invasive breast cancer has the ability to spread but not all invasive cancers do spread, especially if caught early. Cancer grows at different rates in people depending on age, hormone status of the tumor and genetic make up of the person. It is important to understand all of your options regarding treatment. ...Read moreSee 2 more doctor answers
I have invasive ductal carcinoma with lobular features and widespread LVI in a buckshot like pattern after lumpectomy ecad pos lymph nodes pos treat?
What is question: Sorry to hear about your problem but not clear on what your question is. ...Read more
Stage-Dependent: Breast cancers are staged based upon the size of the cancer, lymph node or distant organ involvement, direct extension to the skin or chest wall muscles, and unique molecular features of the tumor. Published rates of 5-yr survival (http://www.Cancer.Org/cancer/breastcancer/detailedguide/breast-cancer-survival-by-stage) vary quite a bit based on these variables, between 15%-93%. ...Read moreSee 1 more doctor answer
Is chemo required for an invasive carsinoma in situ stage 1b grade 2, 0.8 CM in size mastec done, fibroadipose and breast tissue, sentinel lymph clear?
Biopsy: The only way to make a diagnosis of ilc is by biopsy (usually needle biopsy). The problem with ilc is that it often does not show up on a mammogram or sonogram until it is large or a lump can be felt. That is why the diagnosis of ilc is often made later than other types of breast cancer. ...Read moreSee 1 more doctor answer
Is tamoxifen essential in invasive ductal carcinoma (HR+/ER+)?
Does additional chemotherapy is neccesary in stage 1 cancer?
Yes, depends: Yes, anti-estrogen therapy is essential for ER+/PR+ invasive ductal carcinoma. While tamoxifen is used in premenopausal women, femara (letrozole) or arimidex used in postmenopausal women. Some stage I breast cancers (ER+/PR+) do not require further chemotherapy, others do. The need for additional chemotherapy can be assessed by tumor size, recurrence score from a special molecular testing, and etc. ...Read more
Variable: It is well-established that cancer survival is related to timing of diagnosis, however, it's not that simple. Some aggressive cancers may spread very early and others may never regardless of timing. Furthermore, one's overall health (and immune system) may play a major role. Thankfully, most breast cancers are curable. ...Read more
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