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Doctor insights on: Lesions And Calciphylaxis

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Dr. David Wishnew
94 doctors shared insights

Calciphylaxis (Definition)

Calciphylaxis is a condition in which a person (usually somebody with kidney failure) has calcium build-up in small blood vessels of the skin. Calciphylaxis causes painful skin ulcers by clogging off small vessels with calcium, leading to death of affected areas of skin, which ...Read more


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What other conditions could 'focal dermal sclerosis' with telangiectasia on a skin biopsy indicate besides scleroderma?

What other conditions could 'focal dermal sclerosis' with telangiectasia on a skin biopsy indicate besides scleroderma?

Depends on clincial: This depends on your clinical status. It could be scleroderma but may not and may be something else. You need an evaluation ...Read more

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Does idiopathic guttate hypomelanosis appear to look the same as vitiligo spots?

Does idiopathic guttate hypomelanosis appear to look the same as vitiligo spots?

IGH: Igh often looks like little white "confetti" spots on forearms and lower legs. Yes it can look like very small and scattered dots of vitiligo. Your dermatologist will be able to tell. ...Read more

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How much time are lesions present in multiple sclerosis?

How much time are lesions present in multiple sclerosis?

If you have MS, : There are some lesions present in brain white matter or grey matter at all times throughout the disease. On occasion, these lesions may be tough to see on MRI and may be easier visualized in the spinal cord. The idea of therapy is to prevent inflammation and potent meds such as Tysabri (natalizumab) or Gilenya can control the disease quite well. ...Read more

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Where can rashes appear with sarcoidosis?

Where can rashes appear with sarcoidosis?

Rash with sarcoidosi: 25% of patients have rashes as the presentation.The rashes are more common in lower extremities.It can be erythema nodosum, which is raised painful bumps more common in lower extremities, or plaque like rash or reddish brown maculopaoular rash.The rash usually disappear without any treatment i 2 to 4 weeks. ...Read more

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Can lesion on liver be multiple sclerosis?

Can lesion on liver be multiple sclerosis?

Not at all: MS is an inflammatory disease of the brain, spinal cord, and eye, and does not directly affect internal organs. The liver lesion needs diagnosis, and is NOT caused by MS ...Read more

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What are the means by which brain lesions diagnose multiple sclerosis?

What are the means by which brain lesions diagnose multiple sclerosis?

MRI DATA: The diagnosis is certainly based on history and exam, but the MRI is also confirmatory. We discuss "dissemination in time", with lesions emerging and disappearing on serial studies. Also, "dissemination in space", with lesions in different parts of brain and/or spinal cord. Location of lesions are helpful. If there is indication of active inflammation, this prompts aggressive therapy. ...Read more

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MRI=enhancingT2hyperintense foci in both cerebellar regions may represent demyelinating disease. Other less likely metastasis or any infiltrative?

MRI=enhancingT2hyperintense foci in both cerebellar regions may represent demyelinating disease. Other less likely metastasis or any infiltrative?

Complex question.: We will need to discuss your symptoms to figure out the significance of any such "findings" on the MRI. This isn't the forum to discuss- use HealthTap Prime or talk to your doctor / neurologist. In the mean time, obtain the MRI pictures & upload the pictures + report onto your computer. A metastasis in BOTH cerebellums, symmetrically, is ridiculously improbable. Can't say much more here. Good luck ...Read more

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Diagnosed with cushing's disease.Endoscopy found multiple sb lesions, which may represent hamartomas.How can difference be told if cancerous?

Diagnosed with cushing's disease.Endoscopy found multiple sb lesions, which  may represent hamartomas.How can difference be told if cancerous?

Biopsy: Small bowel hamartomas are benign growths that are rare. If there are multiple lesions, your doctor may suspect a genetic syndrome like peutz-jeghers. The good news is that small bowel cancers are also very rare. The only way to tell benign (not cancer) from malignant (cancer) is to biopsy the lesions during an endoscopy if possible. ...Read more

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How commonly are liver lesions benign?

How commonly are liver lesions benign?

It depends: Benign liver lesions are found in routine imaging studies in more than 50% of adults. Even in adults with cancer, only 10% of liver lesions are cancerous. The characteristics of the lesion on the imaging study, the type of imaging study, and the size and number of lesions all play a part in determining the chance a lesion is benign. Radiologists are trained to decide when more tests are needed. ...Read more

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Are there any diseases that can cause lesions on multiple organs (liver,brain,pancreas,etc) besides metastatic cancer?

Are there any diseases that can cause lesions on multiple organs (liver,brain,pancreas,etc) besides metastatic cancer?

Lots: infections such as abscess, parasites, fungus, and amoeba for starters. inflammation of the blood vessels can cause multiple lesions. Certain genetic disorders can affect multiple organs. ...Read more

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Lichen simplex chronicus pathology was done in 2008 saying;biopsy of skin on chin show hyperkeratosis without fungal infestation, spongiotic changes of the epidermis and a superficial perivascular chronic inflammatory cell infiltrate composed of primari

Lichen simplex chronicus pathology was done in 2008 saying;biopsy of  skin on chin show hyperkeratosis without fungal infestation, spongiotic changes of the epidermis and a superficial perivascular chronic inflammatory  cell infiltrate composed of primari

This : This is very challenging without a clinical examination. This could be lichen simplex chronicus, prurigo nodularis, or other possibilities. Certainly i would get it looked at to be sure so i would recommend you see a dermatologist to further evaluate the area. There are many treatment options to helps these conditions. I hope that helps! ...Read more

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How much time are lesions visible with multiple sclerosis?

If a new lesion: Such as an MRI lesion which lights up with gadolinium, this can be actively seen for about 3-4 weeks prior to fading. However, regardless of MRI, there is always pathology even in "normal appearing white matter", unless the inflammatory attack is quelled by potent medications such as Gilenya or Tysabri (natalizumab). ...Read more

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Which cancers are associated with "pruritus scroti"?

Which cancers are associated with "pruritus scroti"?

None of them: If you've got a man itch that doesn't respond to good hygiene and topical tolnaftate or another antifugnal, get seen by your physician. If you have cancer-phobia, learn about the cancer family of diseases and how effective surveillance is in catching them early when they're curable. Stop troubling yourself like this -- life's difficult enough already. ...Read more

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Which disease has more severe consequences dysplastic nevus or melanoma?

Which disease has more severe consequences dysplastic nevus or melanoma?

Melanoma: A dysplastic nevus, unlike a melanoma, is not a true cancer. It is best thought of as a pre-cancer, a possible precursor to melanoma that with time may possibly be able to turn into a true cancer like melanoma. ...Read more

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What are visible symptoms of tuberous sclerosis?

What are visible symptoms of tuberous sclerosis?

Early vs Late: This condition is often first suspected when several skin patches appear with diminished pigment in the shape of an ash leaf on arms, legs, trunk. Over time the skin near the nose is populated with small pimply looking lesions called adenoma sebaceum.Thickened skin areas called shagreen patches are common on the back. ...Read more