Top
20
Doctor insights on: Osteoporosis Physiology

Share
1

1
Metabolic bone disease v. Osteoporosis, what's the difference?

Metabolic bone disease v. Osteoporosis, what's the difference?

Same thing: Osteoporosis is a metabolic bone disease. There are many other metabolic bone diseases. Metabolic bone disease is a catagory of disease. ...Read more

Dr. PHILIP WALLER
1,579 doctors shared insights

Osteoporosis (Definition)

A condition in which bones ...Read more


2

2
Does Fosamax (alendronate) contribute to calcification of heart arteries?

Does Fosamax (alendronate) contribute to calcification of heart arteries?

Fosamax (alendronate) & hearts: Fosamax does not contribute to calcium deposits in the coronary arteries. Fosamax works only on bone metabolism to inhibit the breakdown of bone when exercise, vitamin d and calcium intake are inadquate. ...Read more

3

3
Patho physiology of heart failure in anemi?

Patho physiology of heart failure in anemi?

--: Anemia means low oxygen carrying agents in the blood and this is then compounded with the heart effort to maintain the oxygen delivery to other organs especially the brain by increasing its cardiac output -- and in the presence of a weak heart or other stress factor such as trauma or infection, the heart is overwhelmed and congestive heart failure ensues. ...Read more

4

4
How does psychological stress effect oxidative stress in cancer patients?

How does psychological stress effect oxidative stress in cancer patients?

Awesome question!: Recent study supports the emerging model that chronic stress exposure promotes oxidative damage through frequent and sustained activation of the hypothalamic-pituitary-adrenal axis. It also supports the less studied model of 'eustress' - that manageable levels of life stress may enhance psychobiological resilience to oxidative damage. Best regards. ...Read more

5

5
What system, besides skeletal, does osteoporosis affect?

What system, besides skeletal, does osteoporosis affect?

Just the skeletal: system,but it can cause compression of nerves,,so nerves could bee affected. Hope this helps! ...Read more

6

6
Positive, intense uptake on bone scan, lose spinal hardware, bone marrow edema , family history, paternal taking Forteo to strengthen bones. ??ideas?

Positive, intense uptake on bone scan, lose spinal hardware, bone marrow edema , family history, paternal taking Forteo to strengthen bones. ??ideas?

For one: You probably should remove the hardware. Increased uptake is informing you there is bone activity. You don't state on what phase. This could indicate a fracture or infection.... The doctor should have a clinical suspicion of what he is looking for. If removing the hardware a bone biopsy can be performed if suspecting infection. ...Read more

7

7
How do hormones regulate bone remodeling and osteoporosis?

How do hormones regulate bone remodeling and osteoporosis?

Yes hormones work: Female hormones increase bone density, and the maximum increase is between 9 to 15 years of age. Loss of hormones in women and men for any cause produces loss of bone density of 3% per year for the first year or two then 1% per year. ...Read more

8

8
Can adrenal insufficiency contribute to osteoporosis?

Can adrenal insufficiency contribute to osteoporosis?

Over-treatment: In patients with adrenal insufficiency because of adrenal cortex dysfunction or central acth deficiency, over treating with steroids (ie: hydrocortisone, prednisone, dexamethasone) can certainly lead to osteoporosis. Patients with adrenal insufficiency are closely followed by their endocrinologists. ...Read more

See 1 more doctor answer
9

9
What is thebest method to balance autonomicnervous system(sympathetic hypertonia due to chronic stress formany years)? Symptoms:anxiety,tachycardia...

What is thebest method to balance autonomicnervous system(sympathetic hypertonia due to chronic stress formany years)? Symptoms:anxiety,tachycardia...

Lowdose Beta/Calc bl: Lowdose Beta Block may work. Might start w Metoprolol Succinate (not Tartrate) at 25mgs/d. Physiology: Neg feedback is if U go off equilib U come back. Positive FB is if U go off equil, U go further off. Tachycardia frm Sympath nerves due to anxiety tends to be positive: U feel worse& increa sympa output. With Beta block (CaChan Blk if Beta counterind) can keep sympath system at bay. ...Read more

10

10
Nitric oxide supplements -- what is their role in reducing hypertension and cardiovascular disease?

Nitric oxide  supplements -- what is their role in reducing hypertension and cardiovascular disease?

Nitric oxide: Nitric oxide was thought to be an endothelial relaxation factor which is released from endothelial cells to smooth muscle cells and relaxes them to lower resistance and lower blood pressure. There has been no randomized controlled study to test the benefit of supplements in reducing hypertension or cardiovascular disease. ...Read more

11

11
Osteopenia, osteoporosis or brittle bone disease--differences?

Osteopenia, osteoporosis or brittle bone disease--differences?

Genetic or not: Brittle bone disease is an inherited disorder of bone that is called osteogenesis imperfecta. Osteopenia and osteoporosis are disease of the bone where there is decrease density of the bone. This is associated with age, hormonal change, medications, smoking and other issues. Basically the bone cells are out of balance and take away more bone than they replace. ...Read more

See 1 more doctor answer
12

12
Osteoporosis acth blood level 55(ref range <45). Is it this cause ?

Osteoporosis acth blood level 55(ref range <45). Is it this cause ?

Not likely: High acth itself does not cause osteoporosis. However high cortisol due to high acth (cushings disease) can. You may need testing to make sure you do not have cushings disease. ...Read more

14

14
Can adrenal insufficiency deplete steroids in the human body?

Can adrenal insufficiency deplete steroids in the human body?

By definition: Hi. Yes, adrenal insufficiency is the state of the adrenals being incapable of making enough adrenal steroid hormones (cortisol & aldosterone in primary adrenal insuffic. and cortisol only in pituitary/secondary adrenal insuffic.). Obviously no effect on gonadal steroid hormones. ...Read more

15

15
How does heart failure affect the kidneys relating to anatomy and physiology?

How does heart failure affect the kidneys relating to anatomy and physiology?

HF and kidney: In advanced heart failure the blood flow to the kidneys decrease and then this will lead to less blood perfusion and kidneys get affected. ...Read more

See 1 more doctor answer
17

17
Geriatric epilepsy unknown etiology patient on TEGRETOL . Short memory loss and signs of poor brain circulation(MRI), drugs advised?Cavinton ?

Geriatric epilepsy unknown etiology patient on TEGRETOL . Short memory loss and signs of poor brain circulation(MRI), drugs advised?Cavinton ?

Cerebral blood flow: Carbamazepine is a good agent for seizures, but can be associated with cognitive side effects. If the issue is with blood flow in brain, additional details need to be provided. As for Vinpocetine (Cavinton) there is anecdotal evidence of improvement of blood flow, but there is less experience with that drug in regulated markets (eg US FDA) to comment on usage. ...Read more

18

18
Can stress accelerates the development of type 2 diabetes for 23y guy ?

Can stress accelerates the development of type 2 diabetes for 23y guy ?

Yes it can: Stress can disturb your sleep, and create too much cortisol in your system. If on top of this you overeat (especially processed junk foods) you can gain weight and become Insulin resistant. This paves the road to type ii diabetes. Best to get a handle on your stresses -- and build resilience with exercise, consistent rest, and healthy eating. ...Read more

20

20
"human pancreatic exocrine response to nutrients in health and disease" bmj 2005 figure 2 says lipase post-lundh meal should rise 5x. Is this correct?

"human pancreatic exocrine response to nutrients in health and disease" bmj 2005 figure 2 says lipase post-lundh meal should rise 5x. Is this correct?

Maybe, but...: That graph is a generalization, based on other scientists' studies (one would have to review the original studies). The graph shows pancreatic "enzyme delivery into the duodenum increases rapidly and reaches maximal values within the first postprandial hour", which means it's an estimate of the amount of enzyme put into the small intestine to digest food... Not a measure of lipase on a blood test. ...Read more