Doctor insights on:
Osteonecrosis Of The Jaw Bone
I need bisophanates but am so frightened of the side effects of osteonecrosis of the jaw, thrombosis, stroke, bone cancer etc etc how common are these?
Not so common: And much less common than the dread complications of osteoporosis. I'm not impressed with what i've read about the stroke or cancer risk; good oral hygiene and early recognition should help with the uncommon jaw osteonecrosis. Would like to hear from others about what they've decided. ...Read moreSee 2 more doctor answers
Osteonecrosis is also known as Avascular necrosis. Osteonecrosis is a condition in which part of a person's bone dies due to lack of blood flow to the area. The hip and shoulder are more likely to be affected, but osteonecrosis can also involve the knee, elbow, wrist, or ankle. Trauma to the bone can cause osteonecrosis, often there ...Read more
A drug side-effect: The drugs for osteoporosis and metastatic bone cancer called bisphosphonates (includes fosamax, actonel, boniva, reclast, zometa, aredia) are associated with a side-effect where part of the bone of the jaw dies, the gum sloughs off, and bone shows where the gum was lost. It is treatable but not always curable. It has also been found with bevicizumab, an anti-cancer drug, and after jaw radiation. ...Read moreSee 2 more doctor answers
Low risk: There is a definite but low risk of developing osteonecrosis (dead bone) in patients who have taken fosamax. The risk is higher for other bone building medications taken intravenously. Patients taking Fosamax should discuss any dental procedures with the dentist to see if special precautions must be taken. Sometimes, a 3 month holiday from Fosamax is helpful to minimise the risk of osteonecrosis. ...Read more
Can Spontaneous Osteonecrosis of the jaw (ONJ) be associated with Spontaneous Avascular Necrosis (AVN) especially if you have both conditions?
I have osteonecrosis of the jaw (severe) i need a CT of the brain. Will having a CT make my condition worse?
Rare, but: It is rare with oral bisphosphonates like Fosamax. More common with IV bisphosphonates. However, medicine related osteonecrosis of the jaws (MRONJ) is suck a devastating disease, that precautions are in order for any dental extraction procedure. Oral surgery evaluation recommended for any patient on Fosamaz. ...Read moreSee 1 more doctor answer
Bone is a living growing tissue made mostly of collagen (protein that provides soft framework) & the mineral calcium phosphate that adds strength & hardens the framework. Two types of bone are found in the body; cortical (dense compact outer layer) & trabecular (makes up inner layer, ...Read more
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