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Doctor insights on: Organs Affected By Prions

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How do prions work?

How do prions work?

Not clear: Prions are duplications of Amino Acid chains that populate the brain and crowd out the normal brain components, causing gradual dementia and motor changes and eventually death. There is no known cure. ...Read more

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How do prions enter the body?

How do prions enter the body?

By mouth: These abnormal proteins which can lead to brain degeneration are in food containing brain tissue from affected animals. Herds are checked for this so this incidence is very rare. Cooking does not destroy them. There are probably 1-3 cases of this in the us per year. ...Read more

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What conditions are caused by a prion?

What conditions are caused by a prion?

Slow viruses: Proto-typical disorder include spongiform encephalopathies such as Jakob-Creuzfeldt disease, but also mad cow disease and Kuru. ...Read more

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Can you get prions from cold hot dogs ?

Can you get prions from cold hot dogs ?

Not temp: It's a good question. Many bacterially affected food can be made safe by high temperature. Not so for prion infected meat. This means that whether cold or hot, badly prion infected meat cannot be made safe by heating. The good news is that prion-dangerous beef is exceedingly rare, whether processed or butchered. ...Read more

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Are prions implicated in any human illness?

Yes: Traditionally classified human prion diseases include creuztfeld-jakob diseases (cjd), gerstmann-straussler-scheinker (gss) disease, fatal familial insomnia and kuru. Certain animal prion disease can be transmitted to humans including bovine spongifrm encephalopathy (mad cow disease), chronic wasting disease of mule deer and elk, and scrapie in sheep and goats. ...Read more

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How many known "species" of prions are there?

How many known "species" of prions are there?

Tough question: There are about two dozen known prion diseases caused by more or less distinct prions. Yet the underlying prions do fal, into two large classes. Then there are normal prion type proteins found throughout the body and in the brain. The truth is that this is afield of such new and active research that a solid taxonomy has not yet been developed (so far as i know). ...Read more

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What is necessary for the replication of a prion?

The abnormal protein: Doesn't replicate per se, it produces more of itself by changing the conformation (folding) of the normal cellular protein. These misfolded proteins then begin to agglutinated into plaques which can damage the nerve cell. ...Read more

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What is a prion and what does it do to your body?

What is a prion and what does it do to your body?

Prion: Sub viral protein which infects. Cause of jacob-creutzfeld disease, a dementing illness. ...Read more

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Can you tell me, are prions transmitted this way?

Can you tell me, are prions transmitted this way?

Prion: Prion is translated from the words Transmission & Infection. Its replication is responsible for Neurodegenerative disease. ...Read more

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What's the difference between a plasmid from a prion?

What's the difference between a plasmid from a prion?

Benefit provided: A plasmid is a small, self-replicating segment of bacterial dna (chromosome) that exists only within a cell and are usually of benefit to the bacteria. A prion is a protein that is considered infectious, specifically increasing the number of proteins that become like itself: they can convert proteins to prion status. ...Read more

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