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Doctor insights on: Organophosphate Poisoning

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What signs would you expect to observe if organophosphate poisoning?

What signs would you expect to observe if organophosphate poisoning?

Water everywhere: Ops prevent the breakdown of acetylcholine. Excess of this leads to excess stimulation of the cholinergic nervous system. This is manifest by salivation, lacrimation (tears), sweating, urination, diarrhea, nausea and vomiting. The most concerning symptoms are the "killer b's" - bronchorrhea (fluid in lungs), bronchospasm (spasm of air passages) and bradycardia (slow heart rate) which can kill. ...Read more

Dr. Wm. Marcus Spurlock
259 doctors shared insights

Poisoning (Definition)

Toxic ingestion (also called "poisoning") is a condition in which a person has eaten or drank a substance that causes ill symptoms or damage to his body. Taking an overdose of a medicine, taking any dose of a poison, drinking too much vodka, or accidentally drinking antifreeze . . . are all ...Read more


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How does organophosphate poisoning cause muscular paralysis?

How does organophosphate poisoning cause muscular paralysis?

Inhibits AChE: Organophosphates inhibit acetocholinesterase, which is responsible for recycling actetocholine. This leads to muscle overstimulation and rigid paralysis (amongst other things). ...Read more

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Treating Accidental Poisoning (Tip)

Treating Accidental Poisoning

Do keep the poison control center telephone number in an easy-to-find location for emergencies. ...See more

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Treating Food Poisoning (Checklist)

Go to ER/call Poison Control Center for antidote for serious cases
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If you're vomiting nonstop, go to the ER
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If you have diarrhea, eat something to stop water loss
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If you have excess dehydration, go to the ER for IV fluids
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What are the symptoms of organophosphate poisoning?

List of symptoms...: Muscle weakness, fatigue, muscle cramps, muscle twitching, and paralysis can be seen. Higher blood pressure, lower blood sugar, anxiety, headache, convulsions, and slowed breathing can happen. Visual changes, chest tightness, wheezing from bronchoconstriction, more bronchial secretions, increased salivation, lacrimation, sweating, vomiting, diarrhea, and urination can occur. ...Read more

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How can organophosphate poisoning be treated?

Decontaminate: Atropine injection as soon as possible. Followed by supportive care. Person might need ventilator support for breathing until effects of OP provisioning wears off. ...Read more

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Treating Accidental Poisoning (Tip)

Treating Accidental Poisoning

Do call poison control for specific advice on the poison.Don't make your child vomit unless told to. ...See more

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Treating Accidental Poisoning (Checklist)

Call 911 and poison control immediately
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Protect yourself from exposure if necessary
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Gather any evidence possible about poisoning or exposure
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Remember what and how much substance the person ingested or inhaled
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What happens when you get organophosphate poisoning?

Parasympathetic : Parasympathetic over drive: excess salivation, lung secretions and shortness of breath, incontinence of urine and stool, and coma in severe cases. ...Read more

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How can organophosphate poisoning be treated?

Decontaminate: Atropine injection as soon as possible. Followed by supportive care. Person might need ventilator support for breathing until effects of OP provisioning wears off. ...Read more