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Doctor insights on: Organ Tranplants And Rapamune

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Can phase I trial of proleukin (aldesleukin) and Rapamune lead to type 1 diabetes?

Can phase I trial of proleukin (aldesleukin) and Rapamune lead to type 1 diabetes?

NIH study: The combination of these drugs is being studied in adult patients already diagnosed with type 1 diabetes. The thought is that the combination might help slow down the progress of diabetes. The study isn't complete yet. If there is another phase 1 trial using these drugs in a different study, the investigator should be approached with your question. ...Read more

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Phase I trial of proleukin (aldesleukin) and Rapamune in recent onset type 1 diabetes, what to do?

Phase I trial of proleukin (aldesleukin) and Rapamune in recent onset type 1 diabetes, what to do?

Phase I trials: This is a question best asked of your endocrine specialist. I suppose you are contemplating entering the trial? Do your research and make sure that your questions are answered, be sure that you are willing to make the necessary time commitment. Discuss with family and trusted peers/friends before deciding to join a study. http://clinicaltrials.gov/show/NCT00525889 ...Read more

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Any good results from the phase I trial of proleukin (aldesleukin) and Rapamune in recent onset type 1 diabetes?

Any good results from the phase I trial of proleukin (aldesleukin) and Rapamune in recent onset type 1 diabetes?

Probably not: It appears that a phase 1 trial of these medications was attempted in 2007, but results were never published. This probably means that the trial was abandoned. Years ago, another immunosuppressive med was used (cyclosporin) to treat early Type 1 diabetes and was successful in preserving pancreatic function. However further studies were abandoned because of excessive toxicity of this class of med ...Read more

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How is the eligibility determined for an organ transplant?

How is the eligibility determined for an organ transplant?

Combination: Of state of health, risk of death and indication for the transplant cancer, active infection and other risk factors are ruled out. Finally, patient needs to be compliant with medications and follow up, and free of active addictions. ...Read more

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Can i deny an organ transplant when i die?

Can i deny an organ transplant when i die?

Do you mean...: Do you mean "Can I refuse to donate my organs when I die"? Only you have the right to decide whether you want to donate or not. If you don't sign up to be an organ donor, your next of kin will be asked and he/she will make the decision. ...Read more

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Can you tell me more about organ transplant?

Big topic: Organ transplant means replacing a failed solid organ with a new one. The most common organs transplanted in order are the kidney, liver, heart, lungs, pancreas, and small intestine. The organs come from patients that have died or from living patients that can give one kidney or a piece of liver. The organs will be rejected without the use of powerful anti-rejection drugs. ...Read more

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Why do people need to have an organ transplant?

Organ failure: If a particular organ no longer works transplantation is an option to fix this problem. Sort of like changing a flat tire. ...Read more

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How can I get healthier after an organ transplant?

How can I get healthier after an organ transplant?

Same for others: Eat a nutritious diet and commit to a daily exercise program that fits your age and abilities. Don't smoke, and use alcohol in moderation. ...Read more

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Can you tell me about organ transplant technologies?

Depends upon organs: It really varies depending what kind of transplants.....organs like: Heart, lungs, liver, pancreas, small bowel, kidneys, hand, face etc....bone marrow, stem cell etc.....in anycase doctors will match recipients with the donor before any transplant through very specific immunological tests......better the match....greater the chances of not having any rejection....meaning your body will accept ...Read more

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What are reasons why organ transplant queues are so long?

Availability: Transplant lists are long because the organ is only available after a person dies. So you get the organ if a person does and the organ like a heart lung liver kidney is still healthy. You can donate a kidney and/or part of the liver while you are alive. Humans are living much longer than 100 years ago so we are wearing out our organs. Hope this helps. ...Read more