Doctor insights on:
Orapred Odt Medication
Orapred: "Orapred ODT is contraindicated in patients who are hypersensitive to corticosteroids such as prednisolone or any components of this product. Rare instances of anaphylactoid reactions have occurred in patients receiving corticosteroid therapy." See: http://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1af1b064-b9e0-4354-8e34-dca85b634bbc ...Read more
" Orapred (prednisolone) is a corticosteroid. It prevents the release of substances in the body that cause inflammation.
Orapred is used to treat many conditions such as allergic disorders, skin conditions, ulcerative colitis, arthritis, lupus, psoriasis, or breathing disorders." See: http://www.drugs.com/orapred.html ...Read more
Allergic rash: If your kid is reacting to something with an allergic rash it will take time for the medication to catch up to the allergy. Injections can work faster & I use them sometimes if there is swelling around the eyes or other facial features & or lots of discomfort. Within a day or so the oral steroid should show some progress.If not you can go back in. ...Read more
Croup and steroids: Oral steroids can be very helpful in reducing the severity of upper airway edema associated with croup, but is generally reserved for those children who have severe symptoms such as stridor at rest. Steroids treat symptoms, not the cause, and should be used sparingly in growing children. ...Read more
Great- Get it Early:
Very effective when given in the first 72 hours in this double-blind study http://www.nejm.org/doi/full/10.1056/NEJMoa072006
"In patients with Bell's palsy, early treatment with prednisolone significantly improves the chances of complete recovery at 3 and 9 months. There is no evidence of a benefit of acyclovir given alone or an additional benefit of acyclovir in combination with prednisolone." ...Read more
Depends: On the severity of the hepatitis. The single most important thing in the treatment of alcoholic liver disease is the ABSOLUTE avoidance of alcohol, as well as weight loss in those who are obese/overweight. Several drugs, including pentixophyllin and steroids like methylprednisolone may improve healing, but the prognosis may still be poor if the liver has started to fail. STOP DRINKING ALCOHOL. ...Read more
Not very....: Compared to other drugs, and unfortunately universal side effects. I favor Imuran (azathioprine) or cyclosporine! ...Read more
My daughter's orapred prescription is for 48mg/day for 5 days. She weighs 18.8kg. I thought dose was 1-2mg/kg? Is this too much? She is ex-preemie, 6yo
You are correct: Short courses of oral steroids is indeed usually standardized at 1-2 mg/kg/day for 5 days. The higher dose prescribed is not necessarily cause major issues other than insomnia-more fussy or increased appetite. Talk with you doctor to adjust to 2mg/kg/day if you feel suspicious about the efficacy of the higher prescribed dose. ...Read more
My 3 year old was diagnosed with allergic dermatitis tuesday and proscribed orapred. Her rash has cleared up and then came back worse in some spots.?
See below: Allergic dermatitis can also be similar to atopic dermatitis (eczema). Oral steroids are usually used only for severe flares. The standard for care is moisturizing, moisturizing and moisturizing and then topical steroids for the areas of flare. Moisturizing with ointments is best as these keep the fluids inside of the skin, but may need to be done many times a day. Try this and see if it helps. ...Read more
Kids wit respir illness, airway inflamm, day 3&4 on orapred 2mg/kg, saw doc but no new plan. When do go back in when all short of breath wit min activ?
Call/Be seen: Don't know the age or size of your children or their history but if there is shortness of breath with minimal activity and on a very good dose of oral prendisone, if on adequate doses of albuterol mdi or updraft, I would call your doctor or doctor on call & discuss this with them. If you are concerned, go to the nearest urgent care center or er. Asthma is a serious disease & should be taken so. ...Read more
Son prescribed orapred for croup. Would he still get a fever if he developed pneumonia or sinus infection or do the steroids suppress fever?
My child complains of stomach pain after her dose of orapred. Day6, she vomited after nite dose. 2moro she starts wean to qd. Do I keep on with wean?
Need to call MD: The oropred may be causing gastritis and inflammation of her stomach. If the Prednisone is necessary then your doctor may be able to give her something to counteract it. Usually, if a course of medication is given, the doctor should be consulted if you feel it needs to be changed. ...Read more
Can I administer Orapred (3 ml 2/day) along with breathing treatments (Budesonide or Albuterol)? Baby had croup but now cough sounds rattly.
My daughter,6 years old, has exercise induced and seasonal asthma. She has been cough so much she pukes from bronchitis. She is on proair, augmentin and orapred. We have done steam, cold air ect...nothing is stopping her cough. Anything more we can do?
Not every cough: Come from the respiratory tract, sinuses, middle ears, reflux all can cause or increase cough. The post tussive vomiting you described is typical of uncontrolled asthma, untreated sinusitis or reflux. Orapred burst is fine but still might not have touched the real cause(s). She isn't on controller therapy for her asthma, check aaaai.org or acaai.org for an allergist for comprehensive management ...Read more
3 yo w/croupy cough during URI w/fever. Doc gave orapred. Will orapred make him more susceptible to a secondary infection like pneumonia?
Not sure about less?: If you are taking drugs for a chronic condition like heart disease, diabetes, hypertension, then this a difficult question. If you are concerned about how many pills you are taking in a day, maybe combinations or long acting drugs can reduce the number. Either way, this is to be discussed with your physician since these alternatives are not for everyone. Good luck. ...Read more