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Doctor insights on: Oramorph Sr Of Drugs That Increase Narcotic Effects

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Does Neurontin (gabapentin) increase the effects of methadone?

Does Neurontin (gabapentin) increase the effects of methadone?

Pain meds: Neurontin (gabapentin) is a neuropathic membrane stabilizing medicine that works on neuropathic or nerve pain. It has a different mechanism of action from methadone, which is a narcotic. Many people consider Methadone one of or the most dangerous narcotic because it is linked to abnormal heart rhythms and sudden death. It has a black box warning from the fda stating this. Whatever you can do try to reduce it. ...Read more

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Narcotic (Definition)

A natural or synthetic alkaloid compound that has morphine-like qualities. Other examples are codeine, heroin, Meperidine (demerol). They are classified based on their intrinsic activity & where they interact in the central nervous system. They are involved in pain transmission ...Read more


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Can ativan (lorazepam) increase the effects of tramadol?

Can ativan (lorazepam) increase the effects of tramadol?

Probably: Tramadol is used for pain relief and has less addiction risks than narcotics. Pain can cause anxiety and vise versa. I believe that ativan, (lorazepam) a benzodiazepine that decreases anxiety, can increase effects of tramadol. Reisk of abuse increase though! ...Read more

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Tolerance of Valium -are CNS depressant qualities of this drug also tolerance forming, or just anxiolytic effect?

Tolerance of Valium -are CNS depressant qualities of this drug also tolerance forming, or just anxiolytic effect?

Valium tolerance: When valium induces tolerance, this includes all its cns-depressant effects. It's similar to alcohol, where someone could appear "sober" despite having a high blood alcohol level. If the blood alcohol level dips from usual, withdrawal symptoms may be experienced. ...Read more

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Can taking loperamide increase the effects of hydrocodone?

Can taking loperamide increase the effects of hydrocodone?

Not really: Both will slow down your bowels, possibly causing constipation, but loperamide will not make the effects of hydrocodone (in terms of pain relief) any stronger. ...Read more

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Does bupropion increase the effects of ritalin (methylphenidate)?

Does bupropion increase the effects of ritalin (methylphenidate)?

Interaction risk: There is a potential interaction as both affect dopamine. One possible side effect of bupropion is seizure, and the risk may increase in combination with ritalin (methylphenidate). However, not everyone has this side effect and many experience benefit from using both. Mood difficulties are common with adhd and should be treated. When starting/adding medication it is best to go slow and note any changes or symptoms. ...Read more

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What are the effects of a hydrocodone and lyrica (pregabalin) overdose?

What are the effects of a hydrocodone and lyrica (pregabalin) overdose?

Depressed breathing: which can ultimately lead to coma, brain damage and death. This is mostly from the hydrocodone, but Lyrica (pregabalin) has sedative effects and will contribute to it. In addition, almost all hydrocodone containing pills have acetaminophen (tylenol) in them, and tylenol overdose can cause massive liver failure and death as well. If you are thinking about this, call your doctor or a suicide hotline immediately ...Read more

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What are the potential risks of moderate/high daily alcohol use combined with taking Rx meds Adderall XR (30 mg, 2x/daily) & Xanax (alprazolam) XR (2mg, 2x daily)?

What are the potential risks of moderate/high daily alcohol use combined with taking Rx meds Adderall XR (30 mg, 2x/daily) & Xanax (alprazolam) XR (2mg, 2x daily)?

Major consequences: Combining alcohol in any quantity together with prescription medications & especially those that affect the brain can result in complications. When the quantity of alcohol is as high as you imply then, complications are magnified and can include death. Whoever's involved should seek professional addiction counseling. Questions? www.healthtap.com/drsaghafi Key Code: PDXFNR to make an appointment. ...Read more

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Does caffeine reduce the effect of psychotropic drugs? Particularly Effexor, Buspar, (buspirone) Trazodone, and Topamax.

Does caffeine reduce the effect of psychotropic drugs? Particularly Effexor, Buspar, (buspirone) Trazodone, and Topamax.

No interaction but..: I ran the interaction checker and there is no known interaction between caffeine and any of the meds you mentioned. However, it is well known that caffeine disrupts sleep patterns and can increase anxiety either on it and while withdrawing from it. Therefore, it is best to cut caffeine to a very minimum ...Read more

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Can high doses of anticholinergic (biperiden hydrochloride) decrease the memory?

Can high doses of anticholinergic (biperiden hydrochloride) decrease the memory?

Yes: Amnesia has been reported with biperiden; anticholinergics such as scopolamine are famous for causing amnesia for the events that took place while the patient was taking them. ...Read more

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How sertraline effects methylphenidate metabolism?Can be used to increasing ritalin half life?Best regards.

How sertraline effects methylphenidate metabolism?Can be used to increasing ritalin half life?Best regards.

No: Sertraline does not affect the metabolism of methylphenidate and vice versa. Some unproven but helpful ways to decrease tolerance to stimulants are with magnesium or with memantine. ...Read more

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Please tell me, could mixing percocet with caffeinated acetaminophen asprin raise your opiate tolerance or effect its potency?

Please tell me, could mixing percocet with caffeinated acetaminophen asprin raise your opiate tolerance or effect its potency?

No: But it can expose you to Acetaminophen toxicity. There are already at least 325 mg of Acetaminophen in each tablet. If a person is taking 6 tablets/day, they are at the safe limit of daily tylenol (acetaminophen) ingestion. If you take in additional tylenol (acetaminophen), you are increasing the chance of damaging your liver, without particularly improving pain control or effecting either the opiate tolerance or its potency. ...Read more

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Could Depakote (bipolar medication) increase the potency of vyvance?

Could Depakote (bipolar medication) increase the potency of vyvance?

Drug drug interactio: There are no known drug drug interactions between Depakote and vyvance. ...Read more

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Are the side effects of klonopin similar to taking xanax (alprazolam)?

Are the side effects of klonopin similar to taking xanax (alprazolam)?

Yes and no: Xanax (alprazolam) is a very short acting benzodiazepine and Klonopin is longer acting. Xanax (alprazolam) is much more addictive if used long term, but may act quicker. Neither is good long term as you develop tolerance meaning the same dose is no longer effective. It is better to fo find an antidepressant or a wide variety of other anti anxiety medications. ...Read more

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What are the side effects of ativan (lorazepam) 1 mg?

What are the side effects of ativan (lorazepam) 1 mg?

Mild except if pregn: I agree with dr elliott, and only wish to add that it is important not to use if there is a chance you could get pregnant, or are early in your pregnancy, since it can cause birth defects. ...Read more

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I'm taking flexeral.And oxycodone together. Are there any adverse effects?

I'm taking flexeral.And oxycodone together. Are there any adverse effects?

Sedation: Feeling overly tired can happen. Why are you taking these? Find someone with a goal for your treatment. You are too young to be placed on these medications for any long period of time. ...Read more

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Dr. Norman Cohen
42 doctors shared insights

Oramorph Sr (Definition)

Oramorph SR is a drug that increases narcotic effects which is a ...Read more