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Doctor insights on: Oral Progesterone

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Why does oral progesterone make you drowzy?

Why does oral progesterone make you drowzy?

Gaba receptors: Progesterone taken by mouth gets metabolized into breakdown molecules, some of which stimulate gaba receptors in the brain, which result in sedation or drowsiness. ...Read more

Dr. Seth Derman
1,132 doctors shared insights

Progesterone (Definition)

Progesterone has been found to be helpful in preventing preterm birth in a patient who has a history of delivering babies too early. It can be given as vaginal suppositories. It is most often given as weekly ...Read more


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Can oral progesterone cause iop to increase?

Can oral progesterone cause iop to increase?

IOP: I am not familiar with this term. Could not find it on the web. Could you please elaborate the term for me. ...Read more

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Could oral progesterone tablets be taken vaginally for perimenopause?

Could oral progesterone tablets be taken vaginally for perimenopause?

Progesterone. : Oral Progesterone would not cause harm if used vaginally, but it would make more sense to have it compounded specifically for vaginal use. ...Read more

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Will oral progesterone pills cause sleep disturbance / insomnia trouble?

No: Progesterone is not associated with sleep disturbances or insomnia. It has been used in the past to stimulate ventilation in obese patients, but wasn't really very helpful and it is rarely used for that purpose any more. ...Read more

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I am scheduled for the novasure abalation on the 29th. My doctor put me on an oral progesterone on the 6th. I was under the impression that it was to ?

Ablation: Uterine ablation works best when the uterine lining is thinned out. Progesterone helps thin out the uterus so it is common for doctors to put patients on Progesterone prior to an ablation procedure. ...Read more

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Im 6w2d pregnant & taking oral progesterone due to miscarriage & low prog at pregnant confirmation with ob. My symptoms r disappearing. Is it possible for progesterone to mask the symptoms of a miscarriage?

Im 6w2d pregnant & taking oral progesterone due to miscarriage & low prog at pregnant confirmation with ob.  My symptoms r disappearing.  Is it possible for progesterone to mask the symptoms of a miscarriage?

No: Progesterone will not mask a miscarriage. Progesterone therapy will seldom prevent a miscarriage. Miscarriages are very common - occurring in 1/5 of pregnancies at least. Most miscarriages are due to large chromosomal/ genetic abnormalities which occur at conception. We have no control over these and they seem to be a matter of chance. If you miscarry once again there are further tests to do. ...Read more

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I am taking 30 mg oral progesterone supplement as prescribed by my doc. My period is now 4 days late. Could this delay be from the oral progesterone?

Fool!!: Fool with your hormones, fool with your body. Sure, that can happen. It's a delicate balance down there. Best to discuss with your doctor. Hopefully he or she knows you well, knows your circumstances and the exact reason(s) for the progesterone. If you stop it completely you'll probably let go the red sea. But don't, talk to your own doctor!!! ...Read more

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I had embryo transfer last week on 13th and since yesterday I have heavy period like bleeding and cramps is it possible to have period during the 2 ww period ie after 7 days I am taking the oral progesterone medicines ?

I had embryo transfer last week on 13th and since yesterday I have heavy period like bleeding and cramps is it possible to have period during the 2 ww period ie after 7 days I am taking the oral progesterone medicines ?

Yes: It is not uncommon to have bleeding even while on supplemental Progesterone and still be pregnant. Cramping is sometimes thought to be of uterine origin, but in fact is originating from the ovaries as they begin to regain their normal size after hyperstimulation with gonadotropins or injectable medications. ...Read more

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Taking oral progesterone due to 2 miscarriages. Last period on 7/6. Ovulated & started progesterone 7/24. Sense of smell very strong and sore breasts?

Taking oral progesterone due to 2 miscarriages. Last period on 7/6. Ovulated & started progesterone 7/24. Sense of smell very strong and sore breasts?

Ouch!: The symptoms you are experiencing are likely d/t the Progesterone- remember the breast swelling just before your period? Prog levels are highest then; and that is part of it's function, to also enrich the uterus to sustain pregnancy. First, let me empathize, my wife took Prog to maintain her pregnancy (our only one!) Also, you may get pregnant underneath this, so much the better! Good Luck! ...Read more