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Doctor insights on: Onglyza Medication

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I currently take onglyza (saxagliptin) 5mg and vytoryn 10/20...can I safely take luvox with these medications?

I currently take onglyza (saxagliptin) 5mg and vytoryn 10/20...can I safely take luvox with these medications?

Yes: Hi. Yes, you can take all those drugs together with no predictable adverse effects. Eat healthily, exercise regularly, don't smoke, and control your diabetes and cholesterol! Good luck! ...Read more

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How does drug get its name? Why does it sometimes have two names, e.G. Onglyza & saxagliptin?

How does drug get its name? Why does it sometimes have two names, e.G. Onglyza & saxagliptin?

Trade Name/Clinical: Saxaglipitin is the chemical name which presumably was named by the drug company who created it. Onglyza (saxagliptin) is the brand or trade name saxaglipitin was marketed under. Trade names are chosen for their uniqueness, and drug companies usually undergo extensive public evaluations to determine their acceptance by the public they will be marketed to. ...Read more

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Can latuda be safely used with onglyza (saxagliptin) and tegretol. Do adjustments need to be made to either drugs....Seems may be interactions?

Can latuda be safely used with onglyza (saxagliptin) and tegretol. Do adjustments need to be made to either drugs....Seems may be interactions?

Tegretol interaction: The big problem yes with the tegretol which greatly lowers the blood levels of both Latuda and onglyza (saxagliptin). Your doctor would undoubtedly have to reconsider the use of tegretol, perhaps use Depakote or lithium or no mood stabilizer instead since Latuda is approved for mono therapy in bipolar depression. You've been juggling a lot of interactions between the tegretol and the Lamictal and your diabetes medications. You may be able to simplify things greatly with the addition of latuda. Best wishes and feel free to contact me if you have any further questions. Dr. J. ...Read more

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Do you know any diabetic drug for type 2? I've used onglyza, (saxagliptin) metformin and now glumetza. They all gave me pain.

Do you know any diabetic drug for type 2? I've used onglyza, (saxagliptin) metformin and now glumetza. They all gave me pain.

Type 2 Diabetes meds: There are 6 classes of oral diabetes meds with multiple meds in each class leaving > 20 oral meds to choose from; I'm sure any primary care physician can find ones for you that you will tolerate and control your diabetes. There also several injectable meds not including insulin, which is the most "natural" way to treat diabetes. ...Read more

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My body doesn't tolerate diabetic drugs. I was on onglyza (saxagliptin) and metformin and changed to glumetza 2 days ago and already not responding well. What to do?

Insulin: Might be your only help I you can't tolerate any medication. It is natural and there is no one who can't tolerate insulin. But uncontrolled diabetes will prematurely kill you either by you kidneys, a heart attack, stroke, or before that make you blind. You really need to work with your doctor for your benefit! ...Read more

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Is there a generic drug that compares to onglyza (saxagliptin)? It's very costly. I also take metformin 500 tid & glucotrol ER 10 bid.

Is there a generic drug that compares to onglyza (saxagliptin)? It's very costly. I also take metformin 500 tid & glucotrol ER 10 bid.

No: Unfortunately not. The best way to reduce the cost of medicines for type 2 diabetes is to work on your diet and lose weight so you can be weaned off of some of your medicines. Talk with your doctor about diabetes education classes or seeing a nutritionist. Also, make sure you are exercising, it helps your body's tissues use the glucose in your blood and helps control your blood sugar. ...Read more

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I found onglyza (saxagliptin) may be bad for the pancreas (negative cell multiplication leading to pancreatitis or cancer). Is this drug safe to take?

I found onglyza (saxagliptin) may be bad for the pancreas (negative cell multiplication leading to pancreatitis or cancer). Is this drug safe to take?

Yes if appropriate: There was a huge trial on this drug just got published and no increased risk of pancreatitis or cancer was found. The rate of pancreatitis was 0.3% for both placebo and Onglyza (saxagliptin) group. ...Read more

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Type II diabetic for1 yr. Lost 50 lbs. Thru exercise, diet. Am taking metformin, onglyza, (saxagliptin) lipitor. Is there hope that I can get off these drugs?

Type II diabetic for1 yr. Lost 50 lbs. Thru exercise, diet. Am taking metformin, onglyza, (saxagliptin) lipitor. Is there hope that I can get off these drugs?

Great job!: Yes, there is always hope. Just keep taking care of yourself, eating appropriately with good nutrient-rich food and exercising. Follow closely with your doctor to see what might be able to be reduced and eliminated over time. Keep it up! ...Read more

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Is 5 mg saxagliptin equal to 100mg sitagliptin?

Is 5 mg saxagliptin equal to 100mg sitagliptin?

Approximately yes: It may be approximately but no comparitve studies have been done. Sexaglyptine sold under brand name Onglyza (saxagliptin) has staring dose 2.5 mgm and maximum dose 5mgm. And sitaglyptin sold under brand name januvia starting dose is 50 mgm and maximum dose of 100 mgm daily. ...Read more

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What is the best time to take onglyza--in the morning or at dinner?

Best just at dinner: The best time is to take it just after you finish dinner which is usually the biggest meal for the most ...Read more

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Is their really any difference between onglyza (saxagliptin) and Januvia?

Onglyza (saxagliptin) vs januvia: Yes, there may be some difference. What is your current diabetes status? Please let me know and we can discuss this by email ([email protected] Com). ...Read more

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What is the best time to take onglyza (saxagliptin) with breakfast or supper?

Diabetes: Assuming you have type 2 diabetes? I would please ask your endocrinologist who prescribed it, but usually patients take with breakfast because you do not want any dip in your blood sugar at night.
Please check with prescribing doctor ...Read more

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I qm takng onglyza (saxagliptin) 5 mg once a day. Is there any problem if I swith to sitagliptin 100 mg once a day?

Should not be: But double check with your doc before switching. Better be safe and know all the details about you. ...Read more

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Can luvox be used with vytoryn and onglyza (saxagliptin)?

Can luvox be used with vytoryn and onglyza (saxagliptin)?

Possibly: Luvox (fluxoxamine, an SSRI) is predominantly metabolized in the liver. It can inhibit (slow down) cytochromes in the liver, which r used 2 metabolize other drugs. This would have the effect of increasing the circulating levels of certain other meds. Taking Luvox can increase the blood level of vytorin (ezetimibe and simvastatin) or onglaza. Discuss potential interactions with ur doc & determine the best treatment 4 u :) ...Read more

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Why does onglyza (saxagliptin) have only 2.5mg & 5mg while metformin has 500mg & 1000mg? Why is there big difference in terms of chemical amount?

Why does onglyza (saxagliptin) have only 2.5mg & 5mg while metformin has 500mg & 1000mg? Why is there big difference in terms of chemical amount?

Two different compou: These are two different compounds and belong to different group of medicines, and their effectiveness is based on different dosage. All meds are different compounds and different dosage. ...Read more

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I'm taking onglyza (saxagliptin) 2.5mg and metformin 500mg for a month now. Is this safe? I want to be off these medicines. Will I be cured if taking them?

I'm taking onglyza (saxagliptin) 2.5mg and metformin 500mg for a month now. Is this safe? I want to be off these medicines. Will I be cured if taking them?

No cures: Metformin, available for almost 50 years is very safe in people with good kidney function. The dpp4s - of which Onglyza (saxagliptin) is one - have been implicated in pancreatitis, and pancreas and thyroid cancers. Talk to your doctor if you are worried. ...Read more

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Is it safe to take onglyza (saxagliptin) while pregnant?

Is it safe to take onglyza (saxagliptin) while pregnant?

Category B: It is considered a category b, which means no risk or adverse fetal effects have been shown but no controlled human first trimester studies are available to confirm. There does not appear to be a risk in the second or third trimester. ...Read more

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Is it safe to take onglyza (saxagliptin) and metformin at the same time?

Is it safe to take onglyza (saxagliptin) and metformin at the same time?

Yes: They are a good combination. There is also a pill that combined both of them together called kombiglyze that is fda-approved for the treatment of type 2 diabetes. ...Read more

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Is it safe to take 5 metformin pills & 5 onglyza (saxagliptin) pills on 1 day and take a break for 5 days while fasting?

Is it safe to take 5 metformin pills & 5 onglyza (saxagliptin) pills on 1 day and take a break for 5 days while fasting?

Absolutely not!: There is no rationale for taking metformin or Onglyza (saxagliptin) in that fashion and taking such large amounts all at once may lead to toxic side-effects. ...Read more

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Recently prescribed cardizem 120 daily-concerned about interactions with vytoryn 10/20. Onglyza (saxagliptin) 5mg and andro gel 1.62 -3 pumps?

Sharing metabolism: Cardizem and Simvastatin do share the area of metabolism in the liver called the cyp450 system. Taking them together cause the prolongation of the effect of one another. ...Read more

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My A1c is 6.5. Is that good enough. I want it to be lower to stop taking medicine. Now I take 1 metformin 500mg 1 day and next day have 2.5 mg onglyza (saxagliptin)?

My A1c is 6.5. Is that good enough. I want it to be lower to stop taking medicine. Now I take 1 metformin 500mg 1 day and next day have 2.5 mg onglyza (saxagliptin)?

Good control: Your A1c is very good and at goal. At this level, your risk of getting diabetes complications is low. If you want to lower the amount of pills, try to lose weight if you are overweight or obese. Remain active as this makes your Insulin more sensitive. You should be taking metformin and Onglyza (saxagliptin) everyday instead of alternating every other day. ...Read more

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Does onglyza (saxagliptin) cause pan·cre·a·ti·tis if taken for a long time? Is lupus considered as cancer?

Does onglyza (saxagliptin) cause pan·cre·a·ti·tis if taken for a long time? Is lupus considered as cancer?

Side effect and no.: Pancreatitis is a side effect of onglyza (saxagliptin). Usually side effects are unpredictable complications of a drug, not necessarily related to dose or time interval. Lupus is not cancer. It is type of autoimmune disease that can affect pretty much any part of the body, and sometimes can be quite serious, but it is not cancer. ...Read more

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Is onglyza (saxagliptin) safe for long-term treatment? Has anyone gotten cancer or severe complications from it?

Is onglyza (saxagliptin) safe for long-term treatment? Has anyone gotten cancer or severe complications from it?

Generally safe.: Onglyza (saxagliptin) is not associated with cancer. There are reports of pancreatitis with Onglyza (saxagliptin) and the other dpp-4 inhibitors but that is considered infrequent. Generally Onglyza (saxagliptin) is well tolerated and not associated with significant long term side effects. ...Read more

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I've been on onglyza (saxagliptin) for some time now and recently added metformin for more than a month. Should I watch out for kidney issues & pancreatitis?

I've been on onglyza (saxagliptin) for some time now and recently added metformin for more than a month. Should I watch out for kidney issues & pancreatitis?

Let your Doctor/moni: Metformin is a very safe drug and your doctor will monitor the effectiveness and side effects of metformin with onglyzza. Most common side effect of metformin is gastro intestinal side effects but as you use over time it is well tolerated. Your doctor will monitor your creatinine level as to the safe use of metformin. ...Read more

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As diabetic is glucose of 122 good after 3 hrs of eating? Since it's gone down tremendously, should I lower dosage? Take 2.5 onglyza (saxagliptin) & 500 metformin.

As diabetic is glucose of 122 good after 3 hrs of eating? Since it's gone down tremendously, should I lower dosage? Take 2.5 onglyza (saxagliptin) & 500 metformin.

That's good control: I hope you meant 3 hours after eating. Your blood sugar is not in the hypoglycemic range after eating so you are not getting too much medication. Congratulate yourself (and your doctor) and keep up the good work. ...Read more

Dr. Alan Ali Dr. Ali
2 doctors agreed:
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Take 5mg of onglyza (saxagliptin) for well controlled type 2 diabetes. Want to add luvox....will onglyza (saxagliptin) have to be adjusted?

Dr. Alan Ali Dr. Ali
2 doctors agreed:

Onglyza/Luvox: Yes, since Luvox can increase the blood levels of Onglyza, (saxagliptin) leading to more hypoglycemia. ...Read more

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