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Doctor insights on: Oncogene Antibodies

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Discuss monoclonal antibody production?

Discuss monoclonal antibody production?

Monospecific Ab.: Monoclonal antibodies are those that are produced by the identical immune cells that are descended from the same parent cell. They produce anitibodies that bind to only one epitope or site on an antigen. This means that they are monospecific. This makes them useful in things like research because they can isolate a strain purely and completely. ...Read more

Antibody (Definition)

An antibody is a protein the body's immune system makes to identify potentially harmful substances in the body. Antibodies attach to the substance on a molecular level and mark it so the immune ...Read more


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Describe polyclonal and monoclonal antibody production?

Cells vs, animals: A monoclonal antibody is produced by in-vitro manipulation by expoanding a single cell making a desired antibody. Polyclonal antibodies are usually derived from immunizing an animal and colletcting its blood/serum containing the antibody. Polyclonal antibodies are a mixture of a large number of different cells. ...Read more

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Chemotherapy hormone receptor positive node breast cancer?

Chemotherapy hormone receptor positive node breast cancer?

D/W oncologist: Treatment will depend not only the stage but also the biology of the cancer- whether it is estrogen positive, her2neu positive, whether it is lymph node positive or not. Also depends on your preference and overall health condition. Different test like oncotype dx, mammaprint can give you more info-re- recurrence risk of cancer and will be helpful in choosing the right therapy for you.D/w your md. ...Read more

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Ebvab VCA IgM <36 (range 0-35.9), ebvearly antigenab IgG 37 (0-8.9), ebvab VCA IgG >600 (0-17.9), EBV nuclearantigenab IgG 409 (0-17.9) mono? No mono?

Ebvab VCA IgM <36 (range 0-35.9), ebvearly antigenab IgG 37 (0-8.9), ebvab VCA IgG >600 (0-17.9), EBV nuclearantigenab IgG 409 (0-17.9) mono? No mono?

You had mono...: Your mono-like symptoms likely prompted the testing- i hope you are starting to feel a little better. Testing for different antibodies (igm and igg) against ebv, requires careful interpretation. In early phases of infection, the igm level peaks first followed by a decline; levels of igg peak afterwards, and may remain elevated for quite a while. ...Read more

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Cardiolipin antibodies IgM and urine protein 72mg/l ? Ana negative.

Cardiolipin antibodies IgM and urine protein 72mg/l ? Ana negative.

See details: The urine protein is within normal limits. How strongly positive is the igm cardiolipin. Only high levels of positivity have any clinical significance. Why were the tests ordered in the first place? ...Read more

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Why hasnt monoclonal antibodies cured cancer?

Lack of specific: Target. Your question implies that cancer cells have unique cell surface markers to which monoclonal antibodies could be directed and that is not valid. Tumor cells usually do not have markers not present on normal cells and there is marked variation among tumor cells within a given tumor. ...Read more

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Igg gliadin antibodies abnormal means what?

Igg gliadin antibodies abnormal means what?

Exposure: Basically, this your body's memory protein and tells us that, at some point, you've been exposed to the agent (e.g. Virus, substance, etc...). You should check with your doctor/lab about the significance of specific values. ...Read more

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My serum test is negative for endomysial antibody iga, ttg tissue transglutasminase iga, gliadin antibody igg. But positive for gliadin antibody iga?

My serum test is negative for endomysial antibody  iga, ttg tissue transglutasminase iga, gliadin antibody igg. But positive for gliadin  antibody iga?

Treat the person: Lab tests mean nothing in isolation, and have many false positives and false negatives. The decision to make a trial of a gluten-free diet will be between you and your gastroenterologist or dermatologist based on the big picture. ...Read more

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Human immunodeficiency virus--can it mutate?

Human immunodeficiency virus--can it mutate?

Yes: Hiv mutates in response to HIV therapy. If you're being treated without a complete response (partial suppression), the virus can mutate so it can replicate in the presence of the drugs. This usually happens in people who don't take their medications properly. They can then transmit the mutant virus to others. Spontaneous mutation (mutation independent of therapy) has not been a big problem. ...Read more

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Elevated EBV ab VCA IgG <8 and EBV nucleaer antigen ab IgG test 4.2. & anti-dna(ss)igg ab qn ( 119)& c react protien(5.6) what are implications?

Elevated EBV ab VCA IgG <8 and EBV nucleaer antigen  ab IgG test 4.2. & anti-dna(ss)igg ab qn ( 119)& c react protien(5.6)  what are implications?

Nothing.: Ebv antibodies indicate you had a previous infection, but not active. The c-reactive protein needs a units indicator - that is either normal or somewhat elevated. The anti ss dna is extremely nonspecific and very rarely indicated; I have no idea why that was ordered, discuss with your doctor. ...Read more

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What does a positive NEUTROPHIL CYTOPLASMIC AB.CLASSIC & NEUTROPHIL CYTOPLASMIC AB.PERINUCL & Antinuclear antibodies mean?

What does a positive NEUTROPHIL CYTOPLASMIC AB.CLASSIC	& NEUTROPHIL CYTOPLASMIC AB.PERINUCL & Antinuclear antibodies mean?

See details: This test must be evaluated in the context of the clinical picture. The pANCA and MPO can be positive in several different diseases. ...Read more

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Is antithyroglobulin antibody test the same as thyroglobulin antibody test?

Is antithyroglobulin antibody test the same as thyroglobulin antibody test?

Yes: Both address presence of antibody to the rhyroglobulin molecule made by thyroid gland. See this site for more info. http://www.nlm.nih.gov/medlineplus/ency/article/003557.htm. ...Read more

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How antibody kill an antigen?

They don't usually: Antibody does not usually kill an antigen but binds it. The attachment may then, under certain circumstances , triggers the release of certain mediators or the influx of body cells (cytotoxic lymphocytes, macrophage etc) to do the job of killing. This is a very simplistic answer to a complex question however. ...Read more

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My t3is 108.21 T4 is 10.80 n TSH is 5.43.Antinuclear antibodies is negative. Antithyroglobulin antibodies is <15.0.Peroxidase antibodies is h 100.30?

My t3is 108.21 T4 is 10.80 n TSH is 5.43.Antinuclear antibodies is negative. Antithyroglobulin antibodies is <15.0.Peroxidase antibodies is h 100.30?

Hashimoto's: Your labs showed that you have hashimoto's thyroid disease, an autoimmune thyroid disease that will cause hypothyroidism over time. You are currently subclinically hypothyroid but in light of the positive antibodies, you should talk to your doctor to get treated, especially since you are 24 and is at a reproductive age. Good luck, . ...Read more

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Reactivated EBV 9 months after first infection. Could i be immunodeficient? Antibody count: 65 ab VCA igm; 53 ea ab igg; 431 ab VCA igg; 289 ebna igg.

Reactivated EBV 9 months after first infection. Could i be immunodeficient? Antibody count: 65 ab VCA igm; 53 ea ab igg; 431 ab VCA igg; 289 ebna igg.

No: Unfortunately ebv stays alive forever in one's lymphocytes and can get activated easily in susceptible people without known immunodeficiency. However you may call that an immunodeficiency given that all people have been infected with it yet only few would have recurrent ebv problem. ...Read more

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Are immune globulin antibodies a injection?

Are immune globulin antibodies a injection?

Yes.: They may be given intravenously, intramuscularly, or subcutaneously depending on the dose and usage. ...Read more

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Ebv panel. Ebv nuc antigen igg=157, early ag igg=12.7, EBV VCA igg=112, EBV VCA igm=10.6. Please explain. Concerned about spleen. Symp=fatigue/fog?

Ebv panel. Ebv nuc antigen  igg=157, early ag igg=12.7, EBV VCA igg=112, EBV VCA igm=10.6.  Please explain.  Concerned about spleen. Symp=fatigue/fog?

? Active infection: It's impossible for me to answer with certainty since i don't know the normal ranges your lab uses. If early ag & vca igm are elevated above normal this indicates active ebv infection.I don't know if it is acute or chronic without knowing your history. If chronic i see that as a sign of poor immune function.Immune-boosting herbs/supplements & IV vit c drips may help, but find why immunity is poor. ...Read more

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Thyroid Peroxidase Antibodies 274.0 Anti-Thyroglobulin Antibody 164.4 Mean Platelet Volume 9.1 Erythrocyte Sed Rate 26 Estimat Glomerular Filtratio 43?

Thyroid Peroxidase Antibodies 274.0
Anti-Thyroglobulin Antibody 164.4
Mean Platelet Volume 9.1
Erythrocyte Sed Rate 26
Estimat Glomerular Filtratio 43?

Thyroid and kidneys: Hi. You have antibody evidence of thyroid autoimmunity. It would be nice to know your TSH and free T4. Are you on thyroid hormone? You have diminished kidney function. Do you know why? ...Read more