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Doctor insights on: Oligoclonal Bands Lyme Disease

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How can someone test positive for two Lyme-specific bands on western blot and NOT have been exposed to Lyme disease? What is magic about 5 bands?

How can someone test positive for two Lyme-specific bands on western blot and NOT have been exposed to Lyme disease?  What is magic about 5 bands?

Immune complexities: Lyme disease is caused by a certain type of bacteria called a 'spirochete'- they are a whole class actually of bacteria and believe it or not can be found commonly in the mouth or elsewhere in the environment. You have to reach a certain 'threshold' with Lyme testing because there could be some cross-reactivity coming from these other types of bacteria. The immune system is extraordinarily complex ...Read more

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Oligoclonal Bands (Definition)

Oligoclonal bands are bands of immunoglobulins that are seen when a patient's blood serum, gained from blood plasma, or cerebrospinal fluid (CSF) is analyzed. Oligoclonal bands are an important indicator in the diagnosis of multiple sclerosis. Approximately 79%-90% of all patients with multiple sclerosis have permanently observable oligoclonal ...Read more


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I got a Lyme disease test done.& IgG 66 came positive out of the other 10 bands. What does this mean? Do I have Lyme or had it? Should i worry? Thanks

I got a Lyme disease test done.& IgG 66 came positive out of the other 10 bands. What does this mean? Do I have Lyme or had it? Should i worry? Thanks

Not enough info: This test is not evidence of lyme but also not proof you don't have it! ultimately lyme is a clinical diagnosis. 20-30% of those who have it never have a positive western blot. It's really important that the test include the 31 & 34 bands & most labs don't check it- igenex is the best lab for a thorough test. See a doc who uses igenex as that is someone able to make a proper diagnosis.See comment:. ...Read more

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I tested positive for Lyme disease. I was given the EIA (result 6.1), IgG (10 bands present) and IgM WB (3 bands) Does this mean I've had LD for a whi?

Yes: The presence of IgG usually indicates past infection which might have occurred months or even years ago. The presence of IgM indicates a current or recent infection. ...Read more

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How do you get Lyme disease?

Bite of infected tic: Lime disease is spread by ticks that have acquired the germ in the past and it stays in their system. A tick bite from another of the same species without the ld germ will not do it. The tick must get on your body, settle in for a feeding & feed long enough to pass the germ to you (hours). ...Read more

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Do fleas cause Lyme disease?

Spirochete in fleas: The organism (borellia sp.) that causes lyme disease has been found in fleas and mosquitos but has not yet been found to contribute to transmission of lyme disease in humans this way. ...Read more

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How does Lyme disease spread?

How does Lyme disease spread?

Tick borne: It is transmitted during prolonged blood feeding of the ixodes tick. ...Read more

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How does Lyme disease attack?

How does Lyme disease attack?

See below: Lyme disease is caused by a bacteria called borrelia burgdorferi, named after the scientist willy burgdorfer who discovered the bacterial pathogen - a spirochete (spiral appearing bacteria). It is transmitted by tick saliva but primarily only after being embedded for at least 48 hours. It causes disease by infecting many types of cells and destroying their function. ...Read more

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What does Lyme disease attack?

Many areas: If left untreated it can effect several areas including the heart, brain, peripheral nerves, skin, muscles and joints. ...Read more

Dr. Randy Baker
623 doctors shared insights

Lyme Disease (Definition)

Lyme is caused by borrelia burgdorferi. Acute symptoms can include bullseye rash, headaches, joint pain, fever, and flu like sx. Chronic symptoms can include fibromyalgia symptoms, nerve pain in extremities, mood swings, brain fog, heart problems. Lab diagnosis is not very reliable, and sometimes clinical ...Read more