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Doctor insights on: Oldest Living Child With Holoprosencephaly

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What is the average life expectancy for a child with holoprosencephaly?

What is the average life expectancy for a child with holoprosencephaly?

Undetermined: Potential depends on the severity of the defect and associated features. Many die before birth and most have a brief existence.The defect involves a great range from very major to minor, with longevity matching the degree of defect. See www.ninds.nih.gov/disorders/holoprosencephaly for more information ...Read more

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What other genetic problems might someone have if they have a child with holoprosencephaly?

What other genetic problems might someone have if they have a child with holoprosencephaly?

Maybe none: If I am understanding the question correctly, you're asking if someone who has a child with holoporsencephaly has genetic problems themselves. As dr ferfuson said, this problem is sometimes associated with genetic problems *in the kid.* children with these types of problems can be born from perfectly normal parents. It just happens. To be sure, parents can get tested if they want. ...Read more

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What is holoprosencephaly?

What is holoprosencephaly?

Holoprosencephaly: Holoprosencephaly is a serious central nervous abnormality where the brain does not form normally. It can be associated with chromosomal abnormalities which causes newborns to die, such as trisomy 13. ...Read more

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Semilobar holoprosencephaly, what is this?

Semilobar holoprosencephaly, what is this?

Holoprosencephaly: is a disorder of varying degrees which results from failure of the brain to appropriately divide during the first several weeks of pregnancy. The semilobar form indicates that some division did occur, and it is considered an intermediate form. ...Read more

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Could anyone tell me what holoprosencephaly is?

Could anyone tell me what holoprosencephaly is?

Undivided brain: Most of us have 2 halves in our brain, known as "hemispheres". Holoprosencephaly (HPE) is abnormal division of the embryo's brain and lack of separation of the cerebral hemispheres. HPI can be mild to severe and can cause defects in the development of the face and in brain structure and function. ...Read more

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What happens if holoprosencephaly malformation complex?

What happens if holoprosencephaly malformation complex?

Brain Development: When the embryo's forebrain does not divide to form bilateral cerebral hemispheres (the left and right halves of the brain), it causes defects in the development of the face and in brain structure and function. In less severe cases, babies are born with normal or near-normal brain development and facial deformities that may affect the eyes, nose, and upper lip.The condition can be mild or severe. ...Read more

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What is alobar holoprosencephaly?

What is alobar holoprosencephaly?

Alobar holoprosencep: it is a rare and serious genetic malformation of the brain with adverse short and long outcome ...Read more

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Hi doctors, was just wondering what is alobas holoprosencephaly?

Hi doctors, was just wondering what is alobas holoprosencephaly?

Lobar Holopreosenceh: I believe you are referring to Lobar Holopreosencehaly in which the brain is not formed well leading to severe mental retardation. This is a rare condition from failure of the brain to completely divide into two separate halves. Many parts of the entire brain may be fused and not allow normal function. This may be as a result of some chromosomal disorders. A more complete descriptionfromgeneticist ...Read more

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How is holoprosencephaly malformation complex caused?

Neuronal migration.: Holoprosencephaly is a developmental anomaly typically found in trisomy 13 (patau syndrome) and associated with neuronal migration anomalies resulting in fusion of the cerebral ventricles and hemispheres. ...Read more

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Is there any hope for babies with lissencephaly, porencephaly, holoprosencephaly?

Is there any hope for babies with lissencephaly, porencephaly, holoprosencephaly?

Yes, some.: The fetal/neonatal brain has enough plasticity to allow for mild/moderate porencephalic cases to function at an acceptable level after a long and hard road to recovery. Lissencephaly and holoprosencephaly are developmental disorders of the brain anatomy and usually are manifested with recalcitrant seizures, profound neurodevelopmental delay and limitations to independent living. ...Read more