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Doctor insights on: Older Antihistamines

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Are non-drowsy antihistamines such as Claritin (loratadine) effective for treating asthma?

Are non-drowsy antihistamines such as Claritin (loratadine) effective for treating asthma?

Not directly: Claritin is useful to reduce the symptoms of allergies, especially post nasal drip. It should be used with other medications. Mid you are having serious allergic symptoms that worsen your asthma, see an allergist. ...Read more

Benadryl (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more


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Are there any new, more effective allergy meds than zyrtec, claratin, allegra (fexofenadine)...etc.?

Are there any new, more effective allergy meds than zyrtec, claratin, allegra (fexofenadine)...etc.?

Allergies - hayfever: Everyone is unique and that includes the distribution of histamine receptors that we all have. Thus some anti-histamines work well for some people while other meds don't. It's a matter of finding the right antihistamine for u. Older meds like Benadryl (diphenhydramine) might actually be worth a try. Seeing an allergist would be best as there are new meds just coming out now for allergies (grastek, oralair, Ragwitek ...Read more

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Claritin for children and Benadryl (diphenhydramine) together?

Claritin for children and Benadryl (diphenhydramine) together?

Not recommended: Both Claritin and Benadryl (diphenhydramine) are anti histamines. Claritin is long acting usually used once a day and Benadryl (diphenhydramine) is shorter acting. May be used 3-4 times a day. Since they both have action, recommended not to take it same time. ...Read more

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Dr. Anlin Xu Dr. Xu
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Can Claritin (loratadine) non-drowsy antihistamine still cause drowsiness?

Dr. Anlin Xu Dr. Xu
8 doctors agreed:
Can Claritin (loratadine) non-drowsy antihistamine still cause drowsiness?

Yes: Claritin is a second generation antihistamine which causes much less drowsiness than first generation antihistamine, like benadryl (diphenhydramine). The number of people who feel drowsy on Claritin is so low that it is labeled "non-drowsy". But each of us is unique. I have plenty of patients who feel drowsy on claritin, especially petite women. ...Read more

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Is loratadine less severe than zyrtec (cetirizine)?

Is loratadine less severe than zyrtec (cetirizine)?

Loratadine is weaker: When loradine (claritin) was studied the manufacturer selected the lowest dose that gave a response better than placebo but didn't have more side effects than placebo. This caused it to be a fairly weakly effective med. As it wasn't studied at higher dose i can't speak to safety of higher doses. Personally, i find zyrtec (cetirizine) to be much more effective but may be more sedating. ...Read more

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Can fexofenadine 180 combined with benadryl (diphenhydramine)?

Can fexofenadine 180 combined with benadryl (diphenhydramine)?

Both antihistamines: Fexofenadine is a new generation antihistamine while Benadryl (diphenhydramine) is an old one. While it is safe to take the two together, if symptoms are not controlled, consider seeing an allergist to identify the trigger and develop a better plan. ...Read more

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Is zyrtec (cetirizine) more powerful than OTC allergy medicines?

Is zyrtec (cetirizine) more powerful than OTC allergy medicines?

Zyrtec (cetirizine) is OTC: Zyrtec (cetirizine) is otc and is considered a more potent antihistamine than some others. However everyone responds to medication differently. ...Read more

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Zyrtec or allegra (fexofenadine) for hives: which is the better antihistamine?

Zyrtec or allegra (fexofenadine) for hives: which is the better antihistamine?

Zyrtec (cetirizine): Which drug is better fora specific patient cannot be predicted. I generally try zyrtec first because it does cannot claim not sedating. A little sedation helps alleve itching. Allegra, (fexofenadine) claritn, and Clarinex are allowed to claim no sedation. ...Read more

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Is Claritin comparable to benadryl (diphenhydramine)?

Is Claritin comparable to benadryl (diphenhydramine)?

Both AH: Both act in similar fashion except that Benadryl (diphenhydramine) causes drowsiness and dry mouth in a much higher percentage of people and it works for just a few hours vs claritin's nearly 24 hours duration of action. ...Read more

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Claritin versus Benadryl (diphenhydramine) for kids?

Claritin versus Benadryl (diphenhydramine) for kids?

Work differently: Claritin in a non-drowsy antihistamine. It doesn't cause sleepiness, but you need to use it every day for it to work really well. It's lousy for severe allergic reactions because it takes days to be fully effective. Benadryl (diphenhydramine) causes drowsiness and only lasts for six hours, but is great for severe allergic reactions and works very quickly. If you're exposed and need help now, Benadryl (diphenhydramine) is better. ...Read more

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Is Claritin (loratadine) same as benedryl?

Not exactly: Benadryl (diphenhydramine) is diphenydramine, an old first generation antihistamines that lasts about 6 hours and can cause drowsiness and other side effects. Claritin (loratadine) is a new generation antihistamine that can last 24 hours and has less side effects. At this time, there is no real advantage to benadryl, (diphenhydramine) unless a person also wants some sleep.... ...Read more

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Can adults take children's Benadryl (diphenhydramine)?

Can adults take children's Benadryl (diphenhydramine)?

Sure: Plain Children's Benadryl and plain Adult's Benadryl have the same diphenhydramine ingredient. One just has to decide how many milligrams to take (such as 25mg or 50mg), and then she can figure out how many tablets, capsules, or milliliters of the Children's or of the Adult's formulation to take. If one takes the same number of milligrams, it should not matter which formulation is taken. ...Read more

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I'm looking for a natural antihistamine for seasonal allergies rather than using zyrtec (cetirizine)?

I'm looking for a natural antihistamine for seasonal allergies rather than using zyrtec (cetirizine)?

Natural treatments : Natural treatments are medications too. Usually not as well studied or characterized for benefit and safety as those approved by the fda. I don't know of any natural antihistamines per se but butterbur has been reported to have benefits. A very safe alternative to allergy medicine is buffered saline washes. These can be purchased or home made but certain hygienic guidelines should be followed. ...Read more

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Which is better for allergies zyrtec or claritin (loratadine)?

Zyrtec (cetirizine): Zyrtec (cetirizine) has more anti-allergy or anti-inflamatory effects than clariten (loratidine) and is often better for most allergic symptoms. It does cause drowsiness in some patients. Antihistamines work best when taken at bedtime if you are taking them on a daily basis - as in a pollen allergy or allergy to a pet that lives in your house. ...Read more

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Which is better allegra or claritin (loratadine)?

Allegra (fexofenadine): There is more evidence that Allegra is effective. Claritin (loratadine) is really only marginally effective. ...Read more

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For children's allergies should you combine zyrtec and claritin (loratadine)?

For children's allergies should you combine zyrtec and claritin (loratadine)?

Pick one: While both zyrtec (cetirizine) and Claritin (loratadine) are approved for treatment of allergies in children, it is rarely necessary to use both at the same time. In my experience, Claritin works for many and zyrtec works for most patients. While there is little harm to combining these, it doesn't add to the effectiveness. ...Read more

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Is pseudoephedrine safe for asthma as well as loratadine both in Claritin D because I know Benadryl (diphenhydramine) as an antihistamine is contraindicated ?

Is pseudoephedrine safe for asthma as well as loratadine both in Claritin D because I know Benadryl (diphenhydramine) as an antihistamine is contraindicated ?

Both of those: medications are not contraindicated in asthma. Benadryl (diphenhydramine) is not contraindicated in asthma. Many asthmatics have allergies which are treated with antihistamines of which benadryl (diphenhydramine) is the gold standard. ...Read more

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4 year old with congested cough, can we use claritin (loratadine)?

4 year old with congested cough, can we use claritin (loratadine)?

Treat the cause.: Difficult coughs may be triggered by various causes: lung inflammation, wheezing, sinus drainage, and even reflux. The best way to cope with cough is to treat the actual cause: antibiotics for infxn, inhaled steroids, bronchodilators, or even anti-reflux medications. One or more of these may be needed to quell the cough--even better than traditional cough meds. Claritin (loratadine) is for allergy, not cough. ...Read more

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Are antidepressants potent antihistamines also?

Are antidepressants potent antihistamines also?

Some are, yes.: Looking at receptor inhibition profiles (lab data) we can see that some do indeed block histamine receptors. Older ones in the tca class (elavil, anafranil, etc), trazodone and even a more modern one like Remeron (mirtazapine) do so which can lead to increased sleepiness and appetite. As far as potency, they're not as effective as sudafed in fighting a cold. ...Read more

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Dr. Paul Carter
651 doctors shared insights

Antihistamine (Definition)

Sedating and non-sedating antihistamines prevent and treat allergic reactions, and are ...Read more