Doctor insights on:
Old Granulomatous Disease
What to do if I have hilar calcifications suggesting old granulomatous disease. what does it mean?
Just follow up: Your doctor would explain to you the findings in a better way in context with your clinical picture, at any rate hilar calcification can present old granulomatous disorder or often times just exposure to a fungus "bladtomyces" many people in the southern States are exposed and are asymptomatic and the calcifications just appear on the xray, if no symptoms don't worry and keep your follow up ...Read more
Several posibilities: Granulomas are a result of some inflammatory insult to tissues. In the lung they may represent old fungal infection such as histoplasmosis, or may be tuberculosis (in which case you should have a PPD placed and read so that it is part of your medical history). Non infectious causes also occur, such as sarcoidosis, starch granulomas, foreign body granulomas, and on and on. ...Read moreSee 1 more doctor answer
I just had a chest x-ray that showed minimal old granulomatous disease. Could this cause shortness of breath with minimal exercise (walking up hill)?
Shouldn't: If the lung involvement is truly "minimal" on CXR or CT scan then this shouldn't compromise your lung function enough to cause respiratory symptoms with minimal exercise. Important to determine etiology of lesions first then look for other causes of shortness of breath. Deconditioning, asthma, heart disease are just a few conditions that can be implicated. See Pulmonologist for further evaluation. ...Read more
I was just dx with old granulomatous disease per CT scan. Could this be caused from my 35 yr history of genital herpes?
Not herpes related: Herpes, genital or otherwise, doesn't cause anything like this. These are entirely unrelated problems. Many past infections could cause "old granulomatous disease" detected by chest Xray or CT, and most cases like this turn out not to be serious. But don't take the chance -- follow your doctor's advice about further evaluation. But don't worry at all about herpes. Good luck! ...Read more
I have the same shortness of breath when walking on a incine. Also had a CT with old granulomatous disease. Have hoarseness and right vocal c?
You might be: describing something serious, but hard to tell here. Get to the doctor who ordered the scan to see what is recommended. ...Read more
Chronically inflamed: Tissue due to infection, contains granules. If you were referring to CGD, chronic granulomatous disease, is a primary immune deficiency disorder where the white blood cells, phagocytes do not function well, resulting in chronic granulomatous inflammation in many organs secondary to infections with bacteria and fungi ...Read more
CGD: Chronic granulomatous disease is a genetic defect of white blood cells, specifically polymorphonuclear leukocytes. Granulomas, on the other hand, are a form of pathological change in tissues usually due to infections, but other causes as well, such as sarcoid, foreign bodies, and so on. Whether it is related to your RA can best be discussed with your rheumatologist, and would definitely do this. ...Read more
Immunodeficiency: White blood cells (WBC) roam the various tissues and engulf bacteria and fungi they encounter and then digest them inside themselves. When a crucial molecule, the reactive oxygen species (ros) is not present to enable the killing, the infection is not stopped. So these patients get sick often. ...Read more
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