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Doctor insights on: Nydrazid Medication

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Why doctors consider drugs like ( rifampicin & isoniazid) as risk factor of metabolic syndrome?

Why doctors consider drugs like ( rifampicin & isoniazid) as risk factor of metabolic syndrome?

Metab syndrome: An insulin-sensitizing agent, such as metformin, is often used as hyperglycemia treatment in patients with metabolic syndrome. Literature suggests that metformin may help to reverse the pathophysiologic changes of metabolic syndrome. Cannot find any evidence that Rifampin is a risk factor for metabolic syndrome. ...Read more

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Does TB drugs Rifampicin & isoniazid cause orange vaginal discharge?

Does TB drugs Rifampicin & isoniazid cause orange vaginal discharge?

Rifampicin: Can make your urine red orange(not harmless side effect but can also color your tears, saliva and stool too) and since your urethra is so close to your vaginal opening, it's possible that some of your vaginal discharge is being "stained" red-orange. ...Read more

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Does rifampicin & isoniazid TB drugs cause infertility ? & can tuberculosis cervical lymphadenitis cause infertility?

Does rifampicin & isoniazid TB drugs cause infertility ? & can tuberculosis cervical lymphadenitis cause infertility?

TB and infertility: TB can cause infertility, but usually it does not show any kind of symptoms until the infection has advanced to a severe level and can affect the infertility in women as well as in men. In the woman it causes tuberculosis in uterus and fallopian tubes where as in the man it cause tuberculosis of epididymo- orchitis, as a result of which no sperm can get into the semen. ...Read more

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Does Anti TB drugs i.e rifampicin & isoniazid cause lump on vulva or outer labia majora?

Does Anti TB drugs i.e rifampicin & isoniazid cause lump on vulva or outer labia majora?

Should not: These medications should not cause lumps like that. Please see a doctor as soon as possible for an exam so that they can fine the cause of these lumps for you. ...Read more

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Tb: I have the option to take isoniazid 300mg/day for 9 month side effects: drug induced hepatitis & peripheral neuropathy need another doctor opinion

Tb: I have the option to take isoniazid 300mg/day for 9 month
side effects: drug induced hepatitis & peripheral neuropathy
need another doctor opinion

TB treatment: Most medications will have a long list of possible side effects but that does not mean those things will happen. You need to consider taking the medicine to treat the TB so you will not get sick or spread the infection to your family. Just be sure to take some vitamin b6 to prevent any neuropathy. Never did see any patient have trouble with the isoniazid. Just follow up with your doctor as directe. ...Read more

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What is isoniazid used for?

What is isoniazid used for?

See below:: Isoniazid is used alone or with other drugs to treat tuberculosis (TB) and to prevent it in people who have had contact with tuberculosis bacteria. It eliminates only active (growing) bacteria. Since the bacteria may exist in a resting (nongrowing) state for long periods, therapy with Isoniazid (and other antituberculosis drugs) must be continued for a long time (usually 6-12 months). ...Read more

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What is isoniazid inh taken for?

What is isoniazid inh taken for?

Tuberculosis : Inh is one of drugs used to treat pulmonary tuberculosis. ...Read more

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What are the effects of inh(isoniazid) on my body if taken for 9 months?

What are the effects of inh(isoniazid) on my body if taken for 9 months?

Liver and nerve: Can cause liver problems and nerve problems (neuropathy) like numbness and tingling. Need to monitor these things. ...Read more

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Does isoniazid causes blood problems?

Does isoniazid causes blood problems?

See below:: Isoniazid may cause severe and sometimes fatal liver damage. Tell your doctor if you have or have ever had liver disease or a history of alcoholism or injection drug use. Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your response to isoniazid. ...Read more

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Does isoniazid causes hematologic dysfunction?

Does isoniazid causes hematologic dysfunction?

Yes: Isoniazid causes many adverse reactions. Hepatitis is the most feared. It also can cause peripheral neuropathy, fever, skin rashes and hematologic abnormalities among others. ...Read more

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Is isoniazid and alcohol safe to take together?

Is isoniazid and alcohol safe to take together?

Moderation: Alcohol in reasonable amounts is ok in patients on inh. Both can be hepatotoxic but a glass of wine or a beer is ok. ...Read more

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Do I still have tuberculosus if I took isoniazid for a year?

Do I still have tuberculosus if I took isoniazid for a year?

Probably not: Treatment of latent tuberculosis infection with 9-12 months of daily Isoniazid (assuming excellent adherence) is 80-90% effective in eliminating the latent infection. ...Read more

Dr. Jay Park Dr. Park
1 doctor agreed:
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What are the effects of taking both rifampicin and isoniazid?

Dr. Jay Park Dr. Park
1 doctor agreed:
What are the effects of taking both rifampicin and isoniazid?

Synergistic effect: Latent tuberculosis has been treated for 10 months with Isoniazid alone. In several european countries, 3 months of daily Isoniazid and Rifampin are used to treat latent TB infection with apparent success. ...Read more

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How significant is the risk of drinking when taking isoniazid?

How significant is the risk of drinking when taking isoniazid?

Fairly significant!: Age appeares to be the predominant factor influencing the risk of developing isoniazid-related hepatitis (increasing age is associated with an increasing risk). Drinking alcohol, especially on a daily basis, enhances the risk of hepatitis among those taking isoniazid.Weighing the benefits of Isoniazid in preventing tuberculosis against the risk of its causing hepatitis nec. F/u with your doctor. ...Read more

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What do you advise if I'm taking rifampicin& isoniazid tablet?

What do you advise if I'm taking rifampicin& isoniazid tablet?

Rifampicin/isoniazid: Here are recommendations from Mayo Clinic: http://www.mayoclinic.org/drugs-supplements/rifampin-and-isoniazid-oral-route/precautions/drg-20062747 ...Read more

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Can I start drinking again immediately after finishing isoniazid?

Can I start drinking again immediately after finishing isoniazid?

Wait a bit...: Isoniazid and alcohol consumption is associated with severe and sometimes fatal hepatitis that may occur during and many months after treatment. Risk is related to age and increased with daily alcohol consumption. ...Read more

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My ALT is 142, probably caused by isoniazid. I have taken it for 50 days. Is it a serious issue? Do you think I should stop taking it immediately.

My ALT is 142, probably caused by isoniazid. I have taken it for 50 days. Is it a serious issue? Do you think  I should stop taking it immediately.

No..don't stop just: Isoniazid for a positive TB tine test or gamma interferon assay in the blood (I'm assuming here). We call that Latent TB. Its important to have a doctor monitoring your liver enzymes during this time. While it may seem that 142 is high..its only about 3x normal. As long as your asymptomatic and it doesn't go any higher you should be fine. The standard is 6 months of INH then your done. ...Read more

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Why is isoniazid is prescribed for latent tb?

Why is isoniazid is prescribed for latent tb?

See below:: Isoniazid is used alone or with other drugs to treat tuberculosis (TB) and to prevent it in people who have had contact with tuberculosis bacteria. It eliminates only active (growing) bacteria. Since the bacteria may exist in a resting (nongrowing) state for long periods, therapy with Isoniazid (and other antituberculosis drugs) must be continued for a long time (usually 6-12 months). ...Read more

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Should i be worried i missed 2 doses of isoniazid for tb?

Should i be worried i missed 2 doses of isoniazid for tb?

Missed isoniazid: No, missing only 2 doses of inh would not be a problem. Tb is very slow growing, so missing 2 doses wouldn't be enough time for it to recover and start growing again. ...Read more

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If you had sex and you are taking isoniazid is there any concern?

If  you had sex and you are taking isoniazid is there any concern?

No: Main concern will be whether patient remain compliant with recommended treatment plan. ...Read more

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Why can't you drink alcoholic bevareges when you are taking isoniazid?

Why can't you drink alcoholic bevareges when you are taking isoniazid?

INH hepatitis: Isoniazid (inh) can cause liver damage, and so can alcohol. Drinking alcohol increases the risk of inh hepatitis. ...Read more

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What reactions can Overuse (very long duration) use of INH (isoniazid) cause in the body? Does it do the opposite like cause fungal overgrowth?

What reactions can Overuse (very long duration) use of INH (isoniazid) cause in the body? Does it do the opposite like cause fungal overgrowth?

INH is fairly safe d: It is a relatively safe drug. Its one toxicity of concern is a mild hepatitis which, fortunately is relatively uncommon. There is no risk of fungal infections. You should not take it for any more than one year maximum. If you have taken it for one year, you should be able to stop it after speaking with your treating physician. ...Read more

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Help! really worried? I missed 2 doses of isoniazid for tb?

Isoniazid: "Take the missed dose as soon as you remember. If it is almost time for the next regularly scheduled dose, skip the missed dose and take the next one as directed. Do not take a double dose of this medication." REF: http://www.rxlist.com/isoniazid-tablets-drug/patient-images-side-effects.htm#missdose ...Read more

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What is the definition or description of: Isoniazid allergy?

What is the definition or description of: Isoniazid allergy?

Isoniazid allergy: Isoniazid (isonicotinylhydrazide or INH) is an antibiotic that is used in the treatment of tuberculosis. Medication allergic reactions can include difficulty breathing, hives and swelling of face, lips, throat, mouth or tongue. ...Read more

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Has anyone shown that isoniazid (inh) causes diabetes mellitus?

Has anyone shown that isoniazid (inh) causes diabetes mellitus?

No: While isoniazid is associated with rise in in blood sugar as a side effect, that's a temporary effect - and *not* the same as saying that it causes diabetes, which is very different than saying a person has diabetes, where a person is no longer able to process sugar properly. There are no literature or data showing that isoniazid directly causes people to develop the disease of diabetes. ...Read more

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