Doctor insights on:
Nucynta Morphine Equivalent
Better for what???: Opioids may be all that a person needs for acute pain (broken bone, sprained ankle) but is NEVER the primary treatment of ANY chronic pain. Each of these drugs has a different half-life, side effect and safety profile, and some are better for some people, and some are more dangerous in some people. Methadone is the most dangerous, particularly when given by doctors with less experience using it. ...Read more
?better: I would have to ask "better for what purpose"? ...Read more
OxyContin: Oc (extended release oxycodone) is stonger by a factor of almost twice-that is 15 mg of oc is about equal to 30 mg of MS contin (extended release morphine sulphate). But there is a lot of variability between individuals. Oc seems to be more energizing for some patients and as a result there is more "liking" which is independent of the pain relief. That may explain why there seems to be more abuse. ...Read moreSee 1 more doctor answer
Which is stronger?: Neither hydromorphone (dilaudid) nor OxyContin (oxycodone) is "stronger". "Stronger" effect depends on the dose of the med in equivalents. I notice ur med list includes both of these drugs and lorazepam, a benzodiazepine. All of these meds can cause addiction & all are respiratory depressants. Effects will be additive if taken 2gether. Talk 2 ur doc abt the right medication choices for you. ...Read more
Avinza (morphine): Avinza (morphine) is long acting and once day. Hence it is better as you do not have peaks and troughs. Oxycontin is touted as being designed as q 12 hrs but it usually ends up as a q 8hrs or even a q 6 hrs. It is highly addictive for this reason. This is due to an immediate 30% release portion in each tablet so you get a boost every time you take it - not good for a long acting medication. ...Read moreSee 1 more doctor answer
MS and methadone: I disagree. Both are potent narcotics that can activate the disease of addiction in susceptible patients. The physical withdrawal from Methadone is more prolonged than the withdrawal from morphone but they both can activate addiction. Methadone is used in substitution therapy for other opiate addictions because it gets across the blood-brain barrier more slowly and causes less euphoria & sedation. ...Read more
Better?: Both medications are classified as opioid analgesics meaning they are derived from opium. Ms contin (morphine) is an extended release formulation indicated for constant, chronic pain. These medications should only be prescribed for severe pain. The longterm use of these medications is controversial and should be done under the direction of a qualified physician. ...Read more
Controversial: There are studies on both sides of this issue, with some researchers finding that tramadol did reduce withdrawal, while others finding that it either did very little, or in some cases actually made it worse. A problem is that doses of ultram in the therapeutic range (300-400 mg/day) can cause seizures. My patients have told me mostly that ultram did very little for them, but a few got + results. ...Read more
Med substitution: Yes, the medications can be used interchangeably. ...Read more
What is the equianalgesic dose when comparing 50mg tramadol to Demerol (meperidine hydrochloride)?
What about 30mg codiene to Demerol (meperidine hydrochloride)?
50mg tramadol to Demerol (meperidine hydrochloride)?: Meperidine (Demerol) 50 mg was superior to tramadol 50 mg for acute pain relief in patients with suspected renal colic when given intravenously. Because many patients in both groups received supplemental meperidine and the response to tramadol alone cannot be predicted, clinicians may want to choose higher doses of meperidine alone or other alternative combinations. ...Read more
Yes: Novoprofen is plain ibuprofen, same thing that is in Motrin and many other brands. Depends on what you mean by "stronger" to some extent. If you had inflammation, like a sprained ankle, Ibuprofen is likely to reduce that inflammation over time far more than tylenol (acetaminophen) and oxycodone. However, the oxycodone will have more effects on immediately reducing pain than Ibuprofen does. Also has more risks. ...Read more
Not necessarily.: The peak effect of immediate release morphine and sustained release morphine are different, so, for the addictive personality, the euphoric potential is different. When compared to methadone, only the sustained release formulation of morphine would theoretically be less addictive. The chronic use of either medication can lead to tolerance and dependence, both more common than addiction. ...Read more
If allergic to oxycodone, hydrocodone, morphine, codeine, & butrans & nucynta (tapentadol) do not work for pain, what alternatives are there? Demerol? Dillaudid?
Depends: On many factors, including whether morphine is given by injection or by mouth, or whether in a long-acting or immediate-release short-acting form. In general, by mouth they are equipotent - 5 mg hydrocodone is equivalent to 5 mg morphine. If given by injection, it is about 1.7 mg morphine (about 3 times more potent) to 5 mg. Also depends onhow well liver and kidneys are working in some cases. ...Read more
Intractable pain, scs implanted, high morphine equivalent for survival. Severe constipation.Switched to relistor (methylnaltrexone). Worked 3 times, now 7 days can't go. Was on 12 osmoprep, 2 miralax & 3 colace.What now?
Constipation: You need to seek out the md who manages your scs. It needs to be adjusted. Also morphine may need to be changed to a different drug. Your body may not have the same response to fentanyl or oxycontin. You have to drink at least 8 glasses of water a day and eat foods high in fiber. In addition to the colace and MiraLAX (polyethylene glycol) the medicines are not substitutes for diet they are in addition. ...Read moreSee 2 more doctor answers
When switching from 50mcg (every 72 hours) fentanyl patch to morphine sulfate er. - what dosage is equivalent? Roughly. Thank you :)
Urinary retention: One of the known side effect of narcotics, including morphine, is bladder dysfunction or urinary retention. The mechanism of urinary retention is still not completely understood. It's more common with morphine given by epidural route, but can happen with intravenous or oral morphine as well. Please discuss medication change with your doctor if you continues to experience urinary retention. ...Read more
My friend thought it would be funny to take morphine. I don't what's going on with me i feel so strange..Please help?
I actually have saringomyelia and so far my doctors are only able to give me drugs, taking morphine 160 mg p/day but not helping as much as use to. What should I expect from here on??? I haven't talked to anyone that has had it as long as I. I've had it
Syringomyelia: Many times pain from your condition is caused by damaged nerves. Narcotic medications are not very effective for that kind of pain, especially if you've been on them for a while. Other medicines like gabapentin or nortriptyline may be helpful in decreasing pain. They can make you tired initially, but usually that feeling goes away. ...Read more
Expired morphine: In general expired medications still do work. In the real world (everything else but the usa) especially africa expired medications are used. As long as they are not expired by more than 12 mo. In the usa the fda and the lawyers will be after us if an expired med was given and you had a problem. ...Read more
Morphine dosage: That depends. If you have been on opiates - lortab, percocet, ect. I may be perfectly safe as long as it's given in divided doses - say three times a day where it totals 80mg. For someone who never takes opiates, to take 80 mg of morphine all at once could kill them by supressing respiration. This effect is amplified by alcohol, benzos and medicines like soma (carisoprodol). ...Read more
Continuous infusion: A morphine drip is a continuous morphine intravenous infusion. Pain medications such as morphine can be administered as an infusion to help with constant pain. In some cases, a patient controlled administraion infusion (PCA) system is used whereby you can safely administer yourself an extra dose when needed for severe pain. ...Read more
Morphine is a: controlled substance because it is highly addictive. All controlled addictive substances are dangerous for your health and must be used with caution under a doctor's supervision. ...Read more