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Doctor insights on: Nsaid Induced Renal Failure

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How can nsaids cause renal failure?

How can nsaids cause renal failure?

Prostaglandins: Nsaids inhibit prostaglandins, the bad ones that cause inflammation but also the good ones that help make your stomach coating and help maintain good blood flow in the kidneys. Over time, chronic NSAID use can cause kidney failure. ...Read more

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Dr. Tarek Naguib
587 doctors shared insights

Kidney Failure (Definition)

The kidneys do several tasks. Dialysis is necessary when one or more of the following occur, that can't be remedied or palliated with medications: 1. Insufficient clearance of daily toxins in food and metabolic waste 2. Insufficient clearance of excess water 3. Dangerous electrolyte imbalance, ...Read more


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Pre-renal acute renal failure may occur without systemic hypotension in patients taking nsaid or acei , why ? I just do not get it ?

Pre-renal acute renal failure may occur without systemic hypotension in patients taking nsaid or acei  , why ? I just do not get it ?

Effect blood flow: Nsaids interfere with prostaglandin production in the kidney , some of which may cause blood vessels to dilate. Blocking the prostaglandin production causes the vessels to constrict and decreases blood flow to the kidney. Acei inhibit angiotensin ii production this allows the efferent arteriole to dilate, lowering the hydrostatic pressure in the glomerulous and decreasing kidney function. ...Read more

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What is the difference between acute renal failure and end-stage renal failure?what is asthma ?Can you tell me if someone is put on life support do they induce a coma or can that person b awake just.

What is the difference between acute renal failure and end-stage renal failure?what is asthma ?Can you tell me if someone is put on life support do they induce a coma or can that person b awake just.

A lot of information: acute renal failure when the kidney get insulted right now, and it has the potential to turn around,and becomes normal again. end stage renal disease is when the kidney are no longer working,to the point it required dialysis,and there is no hope of turning around,beside dialysis,patient might need a kidney transplant. not everybody on life support required induced coma,unless the problem in brain. ...Read more

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Should a patient with renal and cardiac issues be given nsaids for pain?

Should a patient with renal and cardiac issues be given nsaids for pain?

Yes and no: Nsaid may be used depending on the particular cardiac and renal condition and their severity.. Please do not take any over the counter nsaids until you speak it over with your physician. ...Read more

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Help plz! Can renal failure be cured entirely?

Help plz! Can renal failure be cured entirely?

Renal failure treatm: Renal failure is irreversible,can be controlled unlikely to be cured,options would be renal dialysis,in end stage failure transplant,,requiring anti rejection meds,even trap landed kidneys can fail ...Read more

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What food can be taken by renal failure patients?

What food can be taken by renal failure patients?

Many: These patients can still eat any foods, but they just need to decrease the amount of potassium and phosphorous containing foods. Just as a diabetic can eat any sweets, they need to limit it. Renal failure patients need to limit total fluids, potassium and phosphorous. If on dialysis, protein is usually encouraged, but if pre-dialysis, high protein intake may not be a good idea. ...Read more

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What is the life expectancy of a person in renal failure?

What is the life expectancy of a person in renal failure?

Weeks: Once kidney function falls below 10% of normal, most patients will develop uremia. This includes progressive weakness and confusion progressing to coma and death, unless some form of kidney replacement therapy is instituted. ...Read more

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Plz tel why renal failure patients should consume low salts ?

Plz tel why renal failure patients should consume low salts ?

BP control: High salt diet promotes water retention which results in elevation in blood pressure and swelling in the legs. The water pills (diuretics) work better if a patient consumes less salt. So if you want good BP control and volume control with less medications than low salt diet is the way to go. ...Read more

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What is acute renal failure?

What is acute renal failure?

Acute renal failure: This is when your kidneys abruptly stop working or greatly slow down in their ability to clean the blood of things that you body does not need..Many substances normally removed by the kidney are potentially harmful if they build up in your blood. Examples of this are too much acid, potentially harmful byproducts of drugs you are taking, and the end products of protein metabolism. ...Read more

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Nsaids (Definition)

Nsaid stands for non steroidal anti inflammatory agent. So the most potent anti inflammatory agents are steroids like prednisone. Nsaids are ...Read more