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Doctor insights on: Novantrone Multiple Sclerosis

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Multiple sclerosis = demyelination?

Multiple sclerosis = demyelination?

Characteristic: Demyelination refers to damage to the coverings of the nerves in the brain and spinal cord, and is very characteristic of the inflammatory process that occurs in ms. This can also occur in children with hereditary leukodystrophies, and can be associated with acquired neurological disorders. The disease modifying drugs in MS are designed to control demyelination and many work well. ...Read more

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Dr. Gregory Moneta
3 doctors shared insights

Sclerosis (Definition)

We neurologists employ the term to describe localized damage involving the central nervous system, and sclerosis means scarring. If in many areas, might be multiple sclerosis. If affecting the motor nerve cell, ...Read more


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Is multiple sclerosis hereditary?

Is multiple sclerosis hereditary?

Complex: Multiple sclerosis is an issue of genetic susceptibility, not the usual heredity, and risk runs about 3-5% if mother has it, 1-2% if father has it. But without specific environmental triggers, the disease will be unlikely to manifest. ...Read more

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Best multiple sclerosis medications?

Best multiple sclerosis medications?

Interferons ? : There is no best medication , some would suit the patient better than others but interferons are the most widely used for prevention of attacks. ...Read more

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Is multiple sclerosis fatal?

Is multiple sclerosis fatal?

Not usually: Ms is a chronic neurological condition, characterized by episodes of neurological disability of variable severity and recovery. A minority of inidividuals can have a very aggressive course, and become so disabled that they are at risk of secondary medical complications which may be fatal. There are subtypes of MS which are so aggressive that a fatal outcome can happen. Fortunately these are rare. ...Read more

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Who discovered multiple sclerosis?

Who discovered multiple sclerosis?

Charcot: The French neurologist Charcot is credited with identifying MS as a distinct entity for the first time. ...Read more

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Is multiple sclerosis preventable?

Is multiple sclerosis preventable?

No: Population studies have suggest that mononucleosis in adolescence, smoking, and possibly childhood obesity are risks for developing ms. However ms is a complex variable disease requiring genetic predisposition along with some environmental trigger(s), possibly influenced by hormones, immune system priming from certain infectious agents. ...Read more

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Is amyotrophic lateral sclerosis a type of multiple sclerosis (ms)?

Not similar diseases: Als is very different, and is a disease of "mis-folded proteins" like alzheimers and parkinson's, and all of these affect older people. Ms is an autoimmune disease afflicting younger patients who have hereditary susceptibilities and environmental exposures. Ms can be successfully treated and controlled, but ALS does not respond well to current therapies. ...Read more

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What symptoms of ms multiple sclerosis ?

What symptoms of ms multiple sclerosis ?

Variable: Please consult this site for information on early symptoms of MS http://www.webmd.com/multiple-sclerosis/guide/multiple-sclerosis-symptoms Wish you good health. ...Read more

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What disease might mimic multiple sclerosis?

What disease might mimic multiple sclerosis?

Several potentials: Cadasil, lupus, arteritis, clippers, pernicious anemia, cervical spondylosis, lyme disease, CNS lymphoma, sjogren's, melas. If you get the point, ms may be hard to diagnose, and often need to exclude other explanations. Patterns may or may not be different, and sometimes it is important to get testing and even several opinions. ...Read more

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What is multiple sclerosis? What is multiple sclerosis?

What is multiple sclerosis? What is multiple sclerosis?

What is MS: Multiple sclerosis is an autoimmune disease that affects the brain, spinal cord, and / or optic nerves. It may cause attacks of symptoms or follow a progressive course. It may affect different areas of the these body parts at different times over many years. It may be either aggressive or benign. ...Read more

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What multiple is sclerosis? What multiple is sclerosis?

What multiple is sclerosis? What multiple is sclerosis?

Multiple : Multiple sclerosis is an autoimmune disease that affects the protective covering around nerves in the spinal cord and brain. I've attached a few good websites below that discuss ms in much more detail. ...Read more

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What is multiple sclerosis? What is multiple sclerosis?

Multiple Sclerosis: http://www.ncbi.nlm.nih.gov/pubmedhealth/pmh0001747/.

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What is multiple sclerosis? What is multiple sclerosis?

What is multiple sclerosis? What is multiple sclerosis?

Multiple sclerosis : Multiple sclerosis is a neurological disorder in which the brain and spinal cord become the target of our own immune system. The myelin, important brain substance that facilitates brain cell communication, gets damaged in multiple areas over time as result of this inflammatory response. Patients symptoms may vary based on the area affected by the inflammation or demyelination. ...Read more

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What is multiple sclerosis?

Autoimmune condition: It is a condition where your own immune system attacks the sheaths (myelin) which covers your nerve fibers. Common symptoms include weakness in muscles due to slow/ damaged nerve conduction. Lowering Inflammation in your body via diet, stress reduction, anti-inflammatory supplements may delay, stabilize and improve the condition. ...Read more

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How is multiple sclerosis diagnosed?

Detective Work: No one diagnostic study can stand alone to conclusively diagnose ms. A neurologist must be a detective, hunting out clues from symptoms suggesting abnormal function in the brain or spinal cord white matter, of appropriate duration (greater than 24 hours) coupled with abnormalities on examination. Mri, spinal fluid, and certain blood tests. This information can help exclude MS mimickers. ...Read more

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What are common therapies for multiple sclerosis?

What are common therapies for multiple sclerosis?

History: Originally, used interferons, such as Avonex, Betaseron, Rebif; and Copaxone. But these are of very mediocre benefit. Tysabri (natalizumab) and Gilenya seem very effective, but now we have Lemtrada, the most potent of all, but very risky. Two other oral agents might be considered, Aubagio and Tecfidera. Plegridy just arrived, but in my opinion is just an updated Avonex. The TIW Copaxone form is easy to use. ...Read more

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What are promising new treatments for multiple sclerosis?

What are promising new treatments for multiple sclerosis?

Many: We have 12 drugs approved to treat MS, and more on the way. The newest are Tecfidera, Plegridy, and the most potent drug of all, Lemtrada. Coming are newer mono-clonal antibodies, a drug to restore myelin damage, and even some treatment for the progressive forms. ...Read more

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Optic neuritis (nmo) or multiple sclerosis (ms)? What are the different victims?

Optic neuritis (nmo) or multiple sclerosis (ms)? What are the different victims?

Say what???: This question is confusing! optic neuritis (abbreviated on) is one of many symptoms of ms and results from inflammation in one or both optic nerves. It is one of the most common symptoms of ms and typically causes eye pain and decreased vision in one eye. It does not typically cause complete blindness. Multiple sclerosis (ms) is an autoimmune disorder of the center nervous system. See below. ...Read more

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How to cure multiple sclerosis ms?

NO cure: In medicine cure is not available for most common conditions control of symptoms and prevention of recurrence is possible in the majority of cases of ms. ...Read more

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Can multiple sclerosis be mis-diagnosed?

Not uncommonly: There are several disease states that can mimic multiple sclerosis, and MRI lesions can likewise be misleading. Since this is so very complex, it is best to seek additional opinions from physicians who specialize in the area, as the diagnosis may not always be easy to reach. ...Read more

Dr. Bennett Machanic
1,447 doctors shared insights

Multiple Sclerosis (Definition)

A progressive disease that interferes with the functioning of the central nervous system and brain. Symptoms include numbness, impairment of speech and of muscular coordination, blurred ...Read more


Dr. David Brandes
148 doctors shared insights

Mitoxantrone (Definition)

Mitoxantrone is a cancer-related antibiotic which is a ...Read more