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Doctor insights on: Nortriptyline Or Amitriptyline

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As a migraine sufferer. I have tried propranolol, amitriptyline, nortriptyline, toprimate and currently on sanomigrain.What would you suggest next.

As a migraine sufferer. I have tried propranolol, amitriptyline, nortriptyline, toprimate and currently on sanomigrain.What would you suggest next.

Migraine treatment: Once a diagnosis of migraine has been made, effective management of migraine involves three specific strategies: 1) patient education, 2) nonpharmacological management (e.g. acupuncture), and 3) pharmacological (medical) management. See an orofacial pain or headache specialist for evaluation and professional management. ...Read more

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Dr. Ravi Chand
243 doctors shared insights

Nortriptyline (Definition)

Classified as a tricyclic antidepressant, and considered of modest benefit these days due to significant anti-cholinergic side effects (drowsiness, dizziness, dryness of mouth, blurring, and perhaps effect on bladder). Confusion may occur in older folks. Had some value in migraine prevention at one point. Used rarely these days as ...Read more


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What is the difference between amitriptyline and nortriptyline? Is one more potent for certain things. Read that nortrip helps tinnitus for instance

What is the difference between amitriptyline and nortriptyline? Is one more potent for certain things. Read that nortrip helps tinnitus for instance

Amitrip or Nortrip: Both drugs are in the same class called tricyclic antidepressants and have similar pharmacologic activity. Amitriptyline is converted by the body to nortriptyline. Amitriptyline tends to cause more sedation and nortriptyline is used when a more stimulatory side effect is desired. Amitriptyline is preferred when nightime drowsiness is desirable. Both drugs, in high doses can cause cardiac toxicity ...Read more

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Which tcas is more potent for sciatica pain relief, amitriptyline(or nortriptyline), imipramine(or desipramine)?

Which tcas is more potent for sciatica pain relief, amitriptyline(or  nortriptyline), imipramine(or desipramine)?

TCA: Tca are classic for neuropathic pain - sciatica for example. Any of the ones u mentioned may be quite eefective - and cheap. They are not without side effects - dry mouth, constipation, sedation. Any of the ones u mentioned can be effective. I personally like amytryptilline - 10mg at night - as mentioned all will work. Additionally other meds such as lyrica, (pregabalin) neurontin, Cymbalta are options. ...Read more

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Amitriptyline vs nortripyline for GI uses and sleep?

Amitriptyline vs nortripyline for GI uses and sleep?

Both are used: But amitrypiline gets my vote based on my personal experience over almost40 years and the other amount of use of this med for other uses than only depression. Nortyptilline is an ok antidepressant for the right patient. ...Read more

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How long should I wait after stopping sam-e before I take Elavil (amitriptyline)?

How long should I wait after stopping sam-e before I take Elavil (amitriptyline)?

I've asked a lot: of MD's this question. Some start you off on the new med right after stopping the old one. Some wait as much as two weeks. You are mixing an herb with a Tricyclic, so I'd play it safe and wait awhile. As a psychiatrist who knows about herbs. Most don't. ...Read more

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Could nortriptyline be ruining my life?

Could nortriptyline be ruining my life?

Nortriptylene: Generally a doctor would prescribe an antidepressant like nortriptylene to help someone's life, not ruin it. Depression itself can ruin a life! but this medicine can also bring side effects like rapid heart rate, dry mouth, constipation, and sexual problems. If you're having symptoms you think may be related to this medicine, it's time to discuss it with your doctor. Other options are available. ...Read more

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Please describe the medication: nortriptyline?

Please describe the medication: nortriptyline?

Older antidepressant: Classified as a tricyclic antidepressant, and considered of modest benefit these days due to significant anti-cholinergic side effects (drowsiness, dizziness, dryness of mouth, blurring, and perhaps effect on bladder). Confusion may occur in older folks. Had some value in migraine prevention at one point. Used rarely these days as better meds are available. ...Read more

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What would you consider a too high of a dose of nortriptyline?

What would you consider a too high of a dose of nortriptyline?

Side effects persist: Established blood level measuring and therapeutic ranges are available to guide dosing and provide feedback if doses threaten safety for example cardiac. Most abandon meds that provide significant side effects. They can be unpleasant but can cause various medical problems in their own right..Weight gain, dry eyes/mouth, urinary hesitancy, sedation, memory problems. All are reversible. ...Read more

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Is 100mg of amitriptyline at bedtime too much?

Is 100mg of amitriptyline at bedtime too much?

No: Maintenance dose: is 150 to 300 mg per day orally in single or divided doses. Ask your doctor for more information. ...Read more

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Should i taper 25mgs of nortriptyline? I was on it for 6 years.

Should i taper 25mgs of nortriptyline?  I was on it for 6 years.

Talk w/psychiatrist: Before making this decision, please discuss it with the doctor who prescribed it for you (hopefully a psychiatrist). Together you need to review the initial problems you were having, and see where you are with them now. Otherwise these could return when the nortriptylene is tapered or stopped. ...Read more

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What is pamelor (nortriptyline) used for?

What is pamelor (nortriptyline) used for?

Pamelor (nortriptyline): Is an old tricyclic antidepressant used for depression, sleep, headache prophylaxis and some neurological ailments with pain. ...Read more

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What are the effects of elavil (amitriptyline)?

What are the effects of elavil (amitriptyline)?

Elavil (amitriptyline): Is an antidepressant with sedating and drying effects, causing heart rate changes, dry mouth/eyes, constipation, depending on dose. It relieves depression, pain of neurogenic origin, headache and insomnia. ...Read more

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Is amitriptyline an maoi?

Is amitriptyline an maoi?

No: It is an antidepressant of the tricyclic group - very different. ...Read more

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Is amitriptyline good for crps?

Is amitriptyline good for crps?

Worth a try: Complex regional pain syndrome is a challenging problem to treat, and your doctors will be trying a number of options to help you. Amitriptylene at low dose may have some positive effects in pain syndromes. If you're not already working with a pain medicine specialist on this problem, you might consider a consultation. ...Read more

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Can i take amitriptyline and quinine?

see details: Quinine has been removed from the prescription shelves in the us. Do not use it. ...Read more

Dr. Robert Kent
375 doctors shared insights

Elavil (Definition)

Elavil is a tertiary amine tricyclic which is a kind of tricyclic type drug (serotonin-norepinephrine reuptake inhibiting ...Read more


Dr. Heidi Fowler
322 doctors shared insights

Endep (Definition)

Endep is a tertiary amine tricyclic which is a kind of tricyclic type drug (serotonin-norepinephrine reuptake inhibiting ...Read more