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Doctor insights on: Normal Mole Vs Cancer

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What percentage of atypical hyperplasia becomes breast cancer?

What percentage of atypical hyperplasia becomes breast cancer?

Small percentage: In a recent study in the annals of surgical oncology, they looked at how many surgical excisions performed for atypical hyperplasia displayed either dcis or cancer. Out of the cases that the study reviewed, only about 1% of the cases upstaged to either dcis or cancer. ...Read more

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Dr. Barry Rosen
4,369 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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Is there any link between oral cancer and thyroid cancer? Had papillary thyroid cancer now suspicious white/red patch on gums that needs biopsy

Is there any link between oral cancer and thyroid cancer? Had papillary thyroid cancer now suspicious white/red patch on gums that needs biopsy

Not aware: Not aware of any link, but if you have a lesion in your mouth that is different from your normal looking gum, go see a doctor or dentist. ...Read more

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Pap thyroid cancer size 7.5mm & invasive ductal breast cancer. ENT said should be ok to remove right half of thyroid only. Opinions?

Pap thyroid cancer size 7.5mm & invasive ductal breast cancer. ENT said should be ok to remove right half of thyroid only. Opinions?

That's fine: If a thyroid lesion is small and there are no nodes palpable and lesion is central in the lobe with a clean isthmus, the chance after a lobectomy of a new lesion forming is about 7%. A hemithyroidectomy here would be fine. ...Read more

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What constitutes stage 4 melanoma on a superficial mole that has gone malignant?

What constitutes stage 4 melanoma on a superficial mole that has gone malignant?

Metastasis: Stage IV (4) melanoma is the highest stage that a melanoma can reach. It is diagnosed by finding distant spread or metastasis to other parts of the body. Stage is different from clark's levels and breslow levels, although these can impact lower stages. (ajcc cancer staging manual, 7th ed., 2010). ...Read more

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Biopsy shows spitz nevus cells under another type of benign mole. Melenoma can't be ruled out yet. Can melanoma grow under a benign mole?

Biopsy shows spitz nevus cells under another type of benign mole. Melenoma can't be ruled out yet. Can melanoma grow under a benign mole?

Yes: In fact, this is fairly common. No one knows where spitz nevus leaves off and a melanoma capable of metastasizing begins. This is one of the hardest calls in pathology, and some say it's impossible. The burning question will be whether to do additional surgery. ...Read more

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Endometrial biopsy normal. What is the percentage that a cervical polyp biopsy is cancerous?

Endometrial biopsy normal. What is the percentage that a cervical polyp biopsy is cancerous?

Small: Cervical polyps are common and are rarely but not never cancerous. Hope that reassures you. Best wishes. ...Read more

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Fna of enlarged cervical node showed atypical cells. Dr. Wants excisional biopsy. What are the chances that this is cancer?

Fna of enlarged cervical node showed atypical cells. Dr. Wants excisional biopsy. What are the chances that this is cancer?

Good chance: Fine needle aspiration (fna) shows atypical cells, means, there is a good chance it could malignant, only way to prove or disprove is by removing the entire node for biopsy for the final diagnosis. ...Read more

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What is the probability of a suspicious mole being cancerous during biopsy?

What is the probability of a suspicious mole being cancerous during biopsy?

100% or 0%: Don't guess odds. A suspicious mole needs to come off. It's either cancer and your life is probably saved, or it's inconsequential. Neglect a suspicious lesion, and there's a fair chance you will pay with your life. A dermatologist can guess malignancy with pretty good accuracy in a suspicious mole, but it's never certain and criteria for moles that should come off are basically scientific. ...Read more

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Could cancer moles only mean skin cancer?

Could cancer moles only mean skin cancer?

Not sure: I'm really not sure how to answer your question. If you have been diagnosed by a pathologist with "cancer moles" that could mean that you have skin cancer, but most doctors do not use a term like "cancer mole". Doctors usually use more specific terms like "squamous cell carcinoma", "basal cell carcinoma", "melanoma", etc. If you could tell me exactly what the pathologist said, i could explain. ...Read more

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What are the odds of having stage 2B invasive ductal carcinoma her2 positive breast cancer and papillary thyroid cancer at age 40?

What are the odds of having stage 2B invasive ductal carcinoma her2 positive breast cancer and papillary thyroid cancer at age 40?

Odds are low.: But it is still possible to have both. Risk of having papillary thyroid before forty is about 13/100,000. Risk of having breast Ca is about 11/100,000. The overlap of the two independent events is slightly less than 1 in a million. ...Read more

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Biopsy report: severely dysplastic keratinizing squamous cells. Does it mean that there is a cancerous growth?

Biopsy report: severely dysplastic keratinizing squamous cells. Does it mean that there is a cancerous growth?

Almost: In your history, you acknowledge you already have been treated for one squamous cell carcinoma of your buccal mucosa. You're only 32 years old. You have a second lesion that is probably going to turn into frank cancer if it isn't already. If you are smoking or chewing tobacco, you must stop now. And this lesion must be treated. Period. Good luck. Stay proactive. ...Read more

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Pap was not normal Endocervical/transformation zone component present. Atypical squamous cells of undetermined significance asc-us What is this cancer?

Pap was not normal Endocervical/transformation zone component present. Atypical squamous cells of undetermined significance asc-us What is this cancer?

Not likely: It's a fairly common finding on Pap smear. It would rarely indicate cancer. Sometimes it means precancerous changes, which are not serious. Needs further evaluation. ...Read more

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Solitary, solid nodule with intranodular flow and follicular neoplasm cells. Afirma came back suspicious. What's likelyhood of malignancy?

Ask your doctor: The doctor who ordered your biopsy has responsibility to explain to you the meaning of the results. If the biopsy shows neoplastic cells, that usually means Cancer cells. But you should get this clarification from your doctor. ...Read more

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Mole grew back 6 weeks after shave. Report compound melanocytic nevus architectural disorder moderate cytologic atypia. What's this mean, melanoma ?

Seek 2nd opinion: Recurrence of a mole makes it likely that it is a melanoma. You should get further surgery done by a melanoma expert(surgical Oncologist). It always useful to seek 2 or 3 opinions and go with the aggregate of the recommendation, provided to you. ...Read more

Dr. Coyle Connolly
1,113 doctors shared insights

Moles (Definition)

A mole (also called a nevus) is a localized overgrowth of pigment-producing cells (melanocytes) in the skin. Most moles are benign. However, these cells can become cancerous. This is known as melanoma, ...Read more


Dr. Coyle Connolly
479 doctors shared insights

Nevi (Definition)

Nevi ...Read more