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Doctor insights on: Normal Cd4 Cell Range In Percentage

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What's the normal range in percentage for cd3, cd4, cd8, cd5, cd19 and cd20 antigens in peripheral blood for female adults?

What's the normal range in percentage for cd3, cd4, cd8, cd5, cd19 and cd20 antigens in peripheral blood for female adults?

Why do you ask?: You are of course talking about percentages of either all white blood cells or of lymphocytes. This question does not arise in general clinical medicine, and if someone has offered this to you without a strong suspicion of immunodeficiency or leukemia, you need to insist on an explanation. And in such workups, the search is either for a mutant clone or a grave deficiency; percentages are moot. ...Read more

Cd4 (Definition)

Is a glyco protein found on surface of immune cells such as monocytes, macrophages & dendritic cells. It assists t-cell receptors in communicating with an antigen-presenting cell, hewnce facilitating entry of HIV virus into the cell. Measuring the CD4 count is used to determine ...Read more


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Hiv neg- immune labs ok "good humoral and T cell function" except- Cd4=527, Range 533-1674. Cd3=717, Range 958-2388. Doc says low. Is it severely low?

Hiv neg- immune labs ok "good humoral and T cell function" except- Cd4=527, Range 533-1674. Cd3=717, Range 958-2388. Doc says low. Is it severely low?

No: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, your counts are not severely low and may be your normal. Why was the test done?
For good health - Have a diet rich in fresh vegetables, fruits, whole grains, low fat milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form.
Practice safe sex. ...Read more

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My "Cd4 + cd3 t cell #" is 560. My lab's range is 533-1674. Does this mean I'm borderline low to have weak immune system?

My "Cd4 + cd3 t cell #" is 560. My lab's range is 533-1674. Does this mean I'm borderline low to have weak immune system?

Clarify: You are reporting a number on the sum of both types of cells and thus there is no way to tell whether one may be very low or not. More importantly, are you having frequent infections or declining heatlh? ...Read more

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What would b the cause of chronic high T cell counts, cd4, 5, 7, and 8. A T-cell beta gene rearrangement, elevated IGG, elevated LGL's, but normal CBC?

What would b the cause of chronic high T cell counts, cd4, 5, 7, and 8. A T-cell beta gene rearrangement, elevated IGG, elevated LGL's, but normal CBC?

Reason for doing it: What was the reason you got this done. In all patients we don't do T cell count, Immunoglobulin level estimation etc. What were your symptoms. Based on your answerc an give a better explanation. In any patient we do CBC- complete blood count with differential count. Only in people with suspected immunodeficiencies/hematological problems-dyscrasias is the term we use, detailed Tcell, B cell, Ig done ...Read more

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If my CD4 count cell is normal or high like 1400 do I have yo be worry about hiv, Staphy infection detected once, and fungi, no fever or flue never?

HIV concerns: You're reporting an excellent CD4 count... But you do have to be careful out there in the world. Infections of all kinds are waiting to make us sick - we should be smart about protecting ourselves AND protecting others. Yes, there are very good treatments out there now for HIV, but who wants to take meds for the rest of their life? I highly recommend talking to partners & being safe all the time! ...Read more

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What's the difference between cd3 and CD4 cells?

What's the difference between cd3 and CD4 cells?

There is differance: Cd3 is expressed on t-cells

cd4 is a subtype of t-cell known as "helper t-cells" (cd4 cells also express cd3)

cd8 is another subtype of t-cell known as "killer t-cells" (cd8 cells also express cd3). ...Read more

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What is the difference between your cd3 and CD4 cells?

What is the difference between your cd3 and CD4 cells?

T-cells: All t-cells in the blood have the cd3 marker on their surface. In addition to having cd3 on them, most t-cells have either CD4 (if they are helper t-cells; th2-like) or cd8 (if they are cytotoxic t-cells; th1-like). There are many other types of t-cells (nkt, th17, treg, tr1, tfoll, th9) that make up a small number of the circulating t-cells. All of these t-cells have cd3 on them as well. ...Read more

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What is the causes of CD4 less than 200 cells per microliter?

AIDS: A CD4 count less than 200 indicates acquired immune deficiency syndrome (AIDS), with the likely cause infection with HIV (human immunodeficiency virus). ...Read more

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What is the meaning of abnormally high (1700) CD4 cell counts?

Not Much: Unless you have a known or documented immune deficiency, there is very little wrong with an elevated CD4 level. If unsure, have the test repeated to confirm the number is correct, then seek assistance from a reputable immunologist. ...Read more

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I know that the cause of CD4 count less than 200 cells per mocroliter is AlDS, I want other causes. ..

AIDS is a syndrome: AIDS is not a cause. It is a syndrome. The cause of the low CD4 count is HIV. Other causes would be some forms of Lymphoma, Lukeimia, Autoimmune disease or other viruses similar to HIV. ...Read more

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What is CD4 and why is the CD4 cells counted in hiv?

What is CD4 and why is the CD4 cells counted in hiv?

Immunity measure: Cd4 cells (helper t cells) are infected by the HIV virus. With time, the number of CD4 cells declines, which increases your risk for certain infections, malignancies, and other complications. Measuring the CD4 count gives you an indication of the health of your immune system, your risk of getting sick, and your response to treatment. ...Read more

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Immumoperoxidase stains show mixed CD3+ T-Cells & CD20+ B-Cells. B-Cells are positive for IgD and bcl-2, do not co-express CD4, CD10 & bcl-6.

Any symptoms?: Do you have any symptoms? What was the source of cells that were tested?
All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that.
For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form.
Practice safe sex, if you have sex.
Get HPV vaccine, if you are under 27 years of age. ...Read more

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Bloodwork came back and just saw that cd4:cs8 ratio is 4.0 and it says an absolute increase in t helper cells was detected. What does this mean?

Nothing: Test results need be interpreted along with the presenting symptoms. Thus an elevated helper cell count (or any blood test) alone usually does not provide a diagnosis. You will need to tell us why the test was obtained in the first place. ...Read more

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What are the symptoms of a low CD4/t cell count?

Immune impairment: CD4 T lymphocytes are the drivers for immune response and thus a low count may be associated with immune impairment such as increased susceptibility to infections. This is a simplistic answer. ...Read more

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Cd4 and cd8 ratio is 4.0 And it says my T cells are elevated. Why does that mean?

See below: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, the data you provided is not a cause for concern. Why was the test done? Do you have any symptoms? What were the results of other tests? It would be best discussed with the doctor who ordered the test. ...Read more

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my WBC was high absolute neutrophils and absolute basophils high absolute lymphocytes were low. As well CD3, helper cells cd4 cd 19 low cd15 16 hig?

See hematologist.: A disease cannot be diagnosed by a blood test and thus you need to discuss the findings with a hematologist or immunologist depending on what kind of disease condition you have especially if this has been a persistently abnormal finding. ...Read more

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In hiv/aids what is the condition when the CD4 counts goes down 200 cell and how much can human lives in hiv/aids?

In hiv/aids what is the condition when the CD4 counts goes down 200 cell and how much can human lives in hiv/aids?

HIV: T cells under 200 means that your immune system is very weak and that any opportunistic infection could be life threatening. It represents the time when an HIV infection officially becomes aids.

However, with effective treatment, and suppression of the virus, the t cells should recover to normal and a normal full length of life becomes possible. ...Read more

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Cd3 + t cell result 823. Cd4+cd3 t cell 559. Been feeling ill for months and no other abnormal tests. Hiv negative. Are these results too low?

Needs investigation: It sounds like you've been suffering for a while with chronic health issues that need thorough investigation. Seeing an Infectious Diseases specialist would be an important place to start, although sometimes more than one expert is needed to solve a difficult case. Lab results need to be interpreted in the right clinical context, so more information is definitely needed here. Hope you can get help ...Read more

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I have a 4.0 cd4: cd8 ratio and it says absolute increase in t helper cells was detected. Is that Indicate HIV? I google it and that's al I see.

I have a 4.0 cd4: cd8 ratio and it says absolute increase in t helper cells was detected. Is that Indicate HIV? I google it and that's al I see.

No: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, the data you provided is not a cause for concern. If you are worried about HIV, get a HIV nucleic acid test.
For good health - Have a diet rich in fresh vegetables, fruits, whole grains, low fat milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form.
Practice safe sex. ...Read more

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What is the reason for a CD4 / cd30 dual positive cell count in a cutaneous lymphoma panel? What does 53% & 2400 absolute count of these cells signal?

Biomarkers in blood: If your blood had a flow cytometry test showing expression of both markers, CD4 and CD30, and you have a lump or lymphadenopathy, then the hemeonc is looking for involvement of blood with T cell lymphomas that contain both markers. Transformed Mycosis Fungoides, spread of cutaneous anaplastic lymphoma which are often CD4+CD30+, or systemic ALCL going to blood could be reasons. Ask hemeonc about above ...Read more

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Does/can a hematologist address cd4 t-cell problems? If not, what type of doctor does?

ID or immunologist: Hello Bi937,

I would recommend seeing an infectious disease specialist first and then perhaps an immunologist depending on recommendations from the infectious disease physician.

Regards,
Dr. Cacho ...Read more

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Hiv need to attach to CD4 cell in order to form. What happen to the virus if HIV enter cut lips but cant attach to cd4, can the virus survive?

Yes: HIV and any virus for that matter just needs a host cell. Does not need to be CD4 cells=T Lymphocytes. The Lymphocytes are the ones that get ultimately the most damage against them. I strongly suggest you get tested if u are concerned and have been sexually active. ...Read more

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What's the signifigance of finding 53% of peripheral blood cd4+ / cd30+ dual positive cells in a cutaneous lymphoma panel? Is this a sign of ALCL?

What's the signifigance of finding 53% of peripheral blood cd4+ / cd30+ dual positive cells in a cutaneous lymphoma panel? Is this a sign of ALCL?

Could be call MD Onc: The most common Cutaneous T cell lymphoma is mycosis fungoides, which are CD4+ but lacks CD30 early on. Once progressed, the CD4 may acquire CD30, and hence transform to a mimic of anaplastic large CD30 + lymphoma. That said, so is coexpression of 53% in blood is unusual for cutaneous CD30 lymphomas, which are CD4+CD30+ yet mostly confined in skin. Systemic forms may show in blood. Call HemeOnc MD ...Read more

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Any connection between low platelets and low cd4 t-cell counts? If a person has both should it be looked into further?

Any connection between low platelets and low cd4 t-cell counts? If a person has both should it be looked into further?

No: Reference ranges are set so that a few percent of healthies fall outside on either side. Only if you're way out of range should these be a concern. Your personal physician knows when to work these up. I trust you know your HIV status; advancing HIV infection is the only illness I know that is likely to drive both into the way-low, and if you're HIV-negative and near-normal range I'd relax. ...Read more

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I am 50 yrs old. I have only 32 CD4 cells....I am HIV positive...And my virus level is 90, 000...Just now I got admitted in hospital... Can I survive?

I am 50 yrs old. I have only 32 CD4 cells....I am HIV positive...And my virus level is 90, 000...Just now I got admitted in hospital... Can I survive?

AIDS: Yes. Of course. You most likely will have a full life. But, you will need to get good health care, take your medications daily and eat and sleep on a regular basis.

I am sorry you did not test earlier. It would have been easier before your immune functions were damaged. But, that does not mean you cannot get better. You can and you will. ...Read more