Doctor insights on:
Norepinephrine Deficiency Symptoms
Extremely rare one:
Some people who suffer from depression are helped with drugs that increase the norepinephrine stores in nerve endings. Drugs such as Effexor (venlafaxine) or wellbutrin do this. Haveing a severe deficiency of these neurotransmitters is very rare and life threatening.
http://www. Ehow. Com/way_6158789_norepinephrine-deficiency-drooling-treatment. Html. ...Read more
Neurotransmitter: Norepinephrine (ne) is a molecule used to carry signals to organs in the body. Ne is present throughout the body including the heart, blood vesssels and brain. Ne work with certain adrenergic receptors. Outside of the brain, ne primarily cause blood pressure to increase. Ne can be given intravenously to support blood pressure. In the brain, it is thought to effect attention and emotion. ...Read moreSee 1 more doctor answer
Catecholemines: Norepinephrine is a hormone produced in the body. There are specific blood tests which can measure these levels in your body. Norepinephrine is related to your bodies "fight or flight" response. It can also related to your mood and possibly depression. ...Read moreSee 1 more doctor answer
Synthesis & Locale: Norepinephrine (ne) and Epinephrine (e) are both sympathomimetic catecholamines that are synthesized in the adrenal medulla and terminals of sympathetic neurons. Along the metabolic pathway, ne is synthesized first -- and when an enzyme adds a methyl group, you have epinephrine. Ne is the main catecholamine in peripheral tissue and sympathetic neurons. E is mostly made in the adrenal medulla. ...Read more
Both: Are made in the adrenal glands of the body and are released in response to a need for increased energy. The fight or flight phenomenon. The biggest difference is that nor-epi causes more vasoconstriction of blood vessels where epi causes more increase in heart rate and cardiac output through contractility. ...Read moreSee 1 more doctor answer
1 extra carbon atom: Epinephrine has 1 more carbon & 2 more hydrogen atoms then norepinephrine. This small difference makes the molecules look different, so they interact differently with receptors, and have different effects. One example: norEpinephrine narrows blood vessels, increasing blood pressure; Epinephrine can narrow some arteries while dilating others, and can raise or lower blood pressure. ...Read moreSee 1 more doctor answer
Wellbutrin (bupropion): Wellbutrin (bupropion) acts by enhancing the levels of serotonin, dopamine, and norepinephrine at the site of each neurotransmitter. For this reason, it's an excellent medication choice for depression and executive functioning, such as conditions with attention and concentration impairments. However, due to its actions upon dopamine, it is relatively contraindicated in psychotic conditions. ...Read moreSee 1 more doctor answer
Be careful!: Norepinephrine (ne) is a molecule used to carry signals to organs in the body. Ne is present throughout the body including the heart, blood vesssels and brain. Ne work with certain adrenergic receptors. Outside of the brain, ne primarily cause blood pressure to increase. Ne can be given intravenously to support blood pressure. In the brain, it is thought to effect attention and emotion. ...Read more
Flight or fight: Remember flight or fight response:focus, energy, motivation. ...Read more
Is there any bad interaction between ecstasy (mdma) and nris (norepinephrine reputake inhibitors)?
Yes: You don't need a bad interaction to have a bad experience with ecstasy. Both have stimulant like properties which can cause flushing, palpitations and psychosis. Ecstasy can be very dangerous in chronic use leading to depression which is hard to treat. It burns out your pleasure centers like Cocaine and other stimulants. ...Read more
What is the dosing range of pristiq (desvenlafaxine). and at what dose does it effect norepinephrine?
Pristiq (desvenlafaxine): Or desvenlafaxine is an SNRI commonly prescribed to treat depression & anxiety (tho FDA approved to treat MDD at this time). The approved dose range is from 50 - 100 mg. However, you should take exactly the dose prescribed by your doc. The med effects norepi at all doses. Talk with your doc about the best way to take your meds & the best treatment strategy for ur depression! Be well! ...Read more
Neurotransmitter: Norepinephrine (ne) is a sympathomimetic catecholamine that is synthesized in the adrenal medulla, in sympathetic neuron terminals, and in the brainstem and pons. Along with serotonin and dopamine, norepinephrine is a neurotransmitter in the brain. "too much" could lead to activation &anxiety. It may enhance some types of aggression in animals, plus impulsivity and episodic violence in humans. ...Read more
Benzodiazepines: Benzodiazepines do not directly reduce norepinephrine release, but they do enhance the inhibitory gaba-a receptor function in the brain so that nerve cells downstream will be less active -- including norepinephrine-firing ones. The end effect is sedation, emotional calming, decreased muscle tone and coordination, decreased memory function, and a host of other changes. ...Read moreSee 1 more doctor answer
To avoid necrosis: Of the skin and subcutaneous tissues in the event of accidental extravasation, i.e. injection of medicine outside of the vein due to very potent vasoconstrictive effect of the drug that can lead to a prolonged spasm of the blood vessels. ...Read more
Read On: Take a look at this link; it may point you in the right direction. ...Read more
Catecholamines: Behavior is much more complex than neurotransmitter levels alone. But norepinephrine (ne) acts mainly in an area of your brainstem called the locus coeruleus. When released, ne triggers the stress response. Ne is also involved in pain, cognition, mood, emotions, movement and blood pressure. Dopamine is involved in regulating mood, pleasure, delusions, psychosis and drug abuse -- and more. ...Read more
They don't: Antidepressants don't actually contain norepinephrine (ne), but several can affect ne reuptake into the neuronal synapse. The result is more ne available in the synapse, one theory of antidepressants' effectiveness. Antidepressants with this kind of activity include tricyclics, effexor, pristiq, cymbalta, savella, (milnacipran) and fetzima. They also affect serotonin reuptake. Wellbutrin affects ne ; da. ...Read moreSee 1 more doctor answer