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Doctor insights on: Nonautologous Transplant

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Life expectancy of myeloma patients after autologous stem cell transplant?

Life expectancy of myeloma patients after autologous stem cell transplant?

Myeloma : There are many things that go into predicting life expectancy of somebody with myeloma who has an autologous stem cell transplant. The rough estimate for somebody getting a transplant in first remission is about 6-7 years now. However, this is something your oncologist or transplant doctor can talk to you about with more specific information. ...Read more

Dr. Louis Gallia
3 doctors shared insights

Transplant (Definition)

In medicine: a transfer from one body or body part to another of an organ (liver, heart, lung, kidney, pancreas bowel) or tissue (hand, face, hair). The immune system fights foreign invaders (like infections) so it will reject transplants from other people (allotransplants) because they look like infections. So transplants usually require drugs to ...Read more


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What is a autologous bone marrow transplant?

What is a autologous bone marrow transplant?

The patient is donor: In case of myeloma certain lymphomas in general patients receive chemotherapy , achieve a response and then have stem cells mobilized from their marrow- frozen- patient goes through high doses of chemo to clear the marrow or kill as many tumor cells as possible and then reinfuse cells back. The idea is that high doses of chemotherapy can cause prolong remission or cure ...Read more

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Peripheral t-cell lymphoma cure: chop induction+ifosfamide/mtx + autologous transplant or romidepsim+brenduximab?

Peripheral t-cell lymphoma cure: chop induction+ifosfamide/mtx + autologous transplant or romidepsim+brenduximab?

Complex problem: Cannot comment with 2 lines of information. Need the entire clinical context. If you seek more detailed information get a formal second opinion. ...Read more

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What's involved in allogeneic stem cell transplantation?

What's involved in allogeneic stem cell transplantation?

Donor matching.: This involves two people: the (healthy) donor and the (patient) recipient. Donors must have a tissue (hla) type that matches the recipient. Matching is performed on three or more loci of the hla gene, and a perfect match at these loci is preferred. Even with this, immunosuppression is often needed due to graft vs host disease. ...Read more

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Are stem cell transplants safe?

Are stem cell transplants safe?

Stem cells safety: Stem cell safety depends on what kind and where it is being used. Embryonic stem cells have been found to be too costly and risky for causing cancers compared to adult stem cells. Bone marrow Stem cell transplants have been used for years for cancers and is safe. see Eyedoc2020.blogspot.com for more info and safety info. ...Read more

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What's allogeneic bone marrow transplantation like?

What's allogeneic bone marrow transplantation like?

BMT from a donor: Allogeneic bone marrow transplantation (bmt) uses another person as the source of stem cells (bone marrow) as opposed to autologous bmt which uses the patient's own cells (usually frozen). Syngeneic bmt uses an identical twin for the donor. Allogeneic donors can be relatives (usually siblings) or totally unrelated. For more info on bmt check out: http://marrow.Org/. ...Read more

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What are the survival rates for cll cancer after donor stem cell transplant?

What are the survival rates for cll cancer after donor stem cell transplant?

Select patients: Allogeneic (donor) stem cell transplants can be conducted using less intensive (non-ablative) regimens with excellent results for patients with CLL. It is not the first line of therapy, since patients can have remissions of several years with simpler therapies. Fatal complications still may occur in 25% of patients, but unlike other treatments, the remainder have a good chance of being cured. ...Read more

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How risky are stem cell transplants?

How risky are stem cell transplants?

Stem Cells: Stem cell injections are now being used to treat painful joints (shoulders, hips, etc), Alzheimers, ALS, Lyme, Cerebral Palsy, etc. Still there are not great published studies proving its benefit in many of these conditions. We have been using limbal stem cell transplants in eye surgery for years with excellent results. See [email protected]: depends on where the stem cell is from & for. ...Read more

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Pancreatectomy with autologous islet cell transplantation: what does this mean?

Pancreatectomy with autologous islet cell transplantation: what does this mean?

Saving insulin: When an islet cell transplant has to be performed it means that the pancreatectomy was total. The pancreas is an exocrine (digestive juice) and endocrine gland from the Islets of Langerhans. When all are removed, islet transplant helps retain endocrine activity including insulin production. ...Read more

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How are organ transplants done?

How are organ transplants done?

See:: http://www.webmd.com/a-to-z-guides/organ-donation-facts

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What are complications post- bone marrow transplant?

What are complications post- bone marrow transplant?

Many!: Risks are lower if you had your own cells (autologous) or a twin's cells (syngeneic), and higher if you had someone else's (allogeneic). There are short-term and long-term risks. Risks include graft vs host disease, infections (some fatal), liver problems, bleeding, cataracts, infertility, heart damage, lung damage, kidney damage, and others. ...Read more

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Are bone marrow transplants painful?

Are bone marrow transplants painful?

Side effects: There are many effects which can be unpleasant like nausea, vomiting, diarrhea amd mouth sores. Depending on how the transplant is done the mouth sores can be severe and painful. There can be abdominal pain or bone pain in some patients. ...Read more

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How is a bone marrow transplant done?

Let me explain: 1-we have to have a donor who donate that, we do collect the bone marrow from him we call this step (harvesting) 2-we have to transplant this marrow to the recipient (patient receiving the bone marrow). 3-both involve special collecting method and method of delivery , done under anesthesia use some big needles to harvest. Some time require small surgery under anesthesia. ...Read more

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How successful are lung transplant surgeries?

Survival data: Very good at 1 year with average us survival of 90 percent. This falls to 50 percent at five years and 10 percent survival at 10 years. That said there are patients who have lived twenty plus years after a lung transplant. ...Read more

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Does stem cell transplantation treat hematologic cancer?

Yes: Stem cell transplant is used to treat leukemias and lymphomas, both are types of hematologist malignancies. ...Read more

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Will a bone marrow transplant cure bone marrow cancer?

Will a bone marrow transplant cure bone marrow cancer?

Yes: However it depends on the type of cancer, if it is in remission or not ,age of the patient and the type of donor. It also depends on the type of transplant, from self or another donor ...Read more

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Are stem cell transplants for multiple myeloma effective?

Are stem cell transplants for multiple myeloma effective?

Yes.: Autologous stem cells transplants (from yourself as donor when in near remission) result in improved progression free survival and probably overall survival. Allogeneic transplant (from someone else) is more complex, and many would consider it experimental. Although the procedure may cure the disease, there are significant complications and risks that may offset the benefits. ...Read more

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What is involved in bone marrow transplant surgery?

Bone marrow transpla: Bone marrow transplant is a procedure that hematologist/oncologists do for certain indication- for instance- in blood cancer like acute leukemia after remission from chemotherapy, or for certain cases of lymphomas, multiple myelomas- etc. It is not a surgery.Please read from this booklet : http://www.Lls.Org/#/resourcecenter/freeeducationmaterials/treatment/bloodmarrowstemcelltransplant. ...Read more

Dr. Amy Friedman
1,120 doctors shared insights

Transplantation (Definition)

Transplantation is the process of transplanting organs from a donor to a recipient and includes surgery ...Read more