Doctor insights on:
Non Small Cell Lung Cancer Vs Adenocarcinoma
Adenocarcinoma-non-small-cell lung cancer. How many people are doing ok after 1 year from diagnosis?
Stage and biology: It depends on the stage, the biology/genetic profiles, the treatment you received, age, overall condition etc. The earlier your stage is the higher your overall survival percentage is- off course providing that you receive the appropriate treatment. Discuss in detail with your oncologist. ...Read moreSee 4 more doctor answers
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
My dad has late 4th stage emphizima and late 3rd early 4th stage adenocarcinoma (small cell lung cancer). Prognosis?
What to do if my dad has late 4th stage emphizima and late 3rd early 4th stage adenocarcinoma (small cell lung cancer)?
See Oncologist: Small cell lung cancer is generally divided into "limited-stage" in which the cancer is confined to one part of the chest treatable by radiation and "extensive-stage" disease in which it has spread to both lungs or other places in the body. Limited stage disease is usually treated with radiation and chemotherapy. Extensive stage with chemotherapy alone at first and possibly some brain radiation. ...Read more
What do you suggest if my father has late 4th stage emphizima and late 3rd early 4th stage adenocarcinoma (small cell lung cancer)?
Deepest condolences: It sounds like your father's time is short. Make it as good a quality time as possible. Talk to each other. Tell him that you love him. If he was a good father, tell him. Ask him to provide a life history for you - video tape it if possible. Consider Hospice care. Be sure you discuss and know his wishes for mechanical ventilation. Be sure he has a will. ...Read more
Are A549 cancer cell lines specific to the Adenocarcinoma sub-type of lung cancer, or does it mean something else?
CA cell line: The A549 cell line originated from a male patients bronchoalveolar lung carcinoma. Cell lines often acquire additional mutations that facilitates their growth in culture. They may not retain all of the characteristics of the original tumor. ...Read more
I am 58y i was diagnosed with lung cancer/adenocarcinoma at stage 4 (where it spread in both lungs). I am currently taking erlotinib. Is it curable?
Nsclc: First of all, a biopsy will need to be done to the lung mass/nodule not only to establish diagnosis but also to find the histology and genetic profile of the cancer. Then, complete staging work-up with pet/ ct scan need to be done to stage the cancer. The treatment will depend on the histology/molecular-genetic mutation status, stage, as well as overall condition and preference of a patient. ...Read moreSee 2 more doctor answers
One type of lung: Cancer. It is not easy to explain. There are multiple subtypes within in this type. These are due to smoking and tend to spread locally as compared to early spread through blood for small cell cancer. See this site for more info. http://www.cancer.gov/cancertopics/pdq/treatment/non-small-cell-lung/patient/page1. ...Read moreSee 1 more doctor answer
The stage and others: Will depend on the stage and other prognostic factors. In general, the 5 year overall survival for stage 1 is 60-80%., stage 2 is 40-50%; stage 3 is 10-23%, and stage 4 is less than 10%. These however are the statistics obtained when using regular cytotoxic chemotherapy. With more personalized and more targetted therapy-we are hoping the number will improve. ...Read moreSee 2 more doctor answers
Often cures: Surgery is the standard of care for stage i and ii lung cancer in the physically fit patient, and should be considered as an option in many patients with stage iiia. Often can be done minimally invasively thorascopically or with a robot. Recovery varies with the level of invasiveness. Lung surgery has best outcomes by a board certified thoracic surgeon. ...Read moreSee 1 more doctor answer
Robot or VATS: Optimal lung cancer surgery, in appropriate candidates, is anatomic lobectomy (part of lung) or pneumonectomy (whole lung). Complete lymph node sample or dissection is integral part of case. Traditional centers use thoracotomy as primary approach. Modern minimally invasive approaches include vats and robotic techniques. Optimal lung cancer treatment is by comprehensive multidisciplinary approach. ...Read moreSee 2 more doctor answers
Depends on stage: Lower stage non-small cell lung cancer (nsclc) has better survival based on stage appropriate therapy than later stage tumors. The standard of care therapy for stage i and ii nsclc is surgery. For stage iiia chemoradiation followed by surgery or chemoradiation alone and stage iiib and IV chemotherapy +/- radiation. ...Read moreSee 2 more doctor answers
She was diagnosed with non small cell lung cancer stg. 4 and died 29 days later. Before she was diagnosed she seemed fine. How could this happen?
Small cell cancer: Most cancers have a volume doubling time of about 3 months, except small cell cancer. Problem with small cell cancer is that it goes fast, may have no symptoms initially and can go be in multiple organs the time it is diagnosed, and can include the lining of the heart and can cause fluid and compression of the heart. ...Read moreSee 2 more doctor answers
Is biopsy the only way of determining the sub-type of Non-Small Cell Lung Cancer? Any non-invasive ways? 1st biopsy inconclusive and risks with repeat
Need a biopsy: A physician who diagnosed ANY lung cancer without obtaining a biopsy would be committing gross malpractice. You've got SOMETHING in your lung that's VERY worrisome and whatever got it noticed, you should be demanding that the biopsy be repeated anyway and a best diagnosis rendered. Risks? Do you want to die of a missed cancer? I know you don't. Be brave. Best wishes. ...Read more
Not enough space: Let's see: most common category of lung cancer, often but not always tobacco related, treated with surgery if possible but radiation and chemo are often used as well. I suggest you visit the national cancer institute website. It's has good info regarding all kinds of cancers. ...Read more
It depends;: Unfortunately lung cancer is usually diagnosed in more advanced stages because it can be silent. Depending on the region it involves, symptoms could varry from cough, weight loss, shortness of breath, coughing up blood, affecting voice quality. If cancer is found incidentally in early stages( patient not symptomatic and cancer found incidentally), the cure rate can be excellent. ...Read moreSee 2 more doctor answers
Stage is key: The stage or amount of cancer present helps determine if surgery, or other treatments are the best first step. The early stages are best treated with surgery. Sometimes chemotherapy and radiation are used. There is no single way to say what is the best treatment. ...Read moreSee 2 more doctor answers
Not good: Stage 3b non-small-cell-lung cancer is a very heterogeneous group of patients and as such there is no unanimous hard data on survival, unlike the earlier stages. Some may benefit from chemo- and radiation therapy to shrink the tumor and be resected. My advice is to go to the most renowned lung cancer specialist that is available to you and hope for the best. ...Read moreSee 1 more doctor answer
Depends on Stage: The answer to that question depends greatly on how advanced the cancer is when it is diagnosed. That, in turn, depends on how big the tumor is, where it is located, whether it has spread locally or all over the body. Generally, the earlier you catch the cancer, the longer the survival is. That is not a 100% "take it to the bank" rule, but it is a general pattern. A number of tests find out stage. ...Read moreSee 1 more doctor answer
Depends: That depends on where the tumor is: if it is spread to a vital organ, it will causes symptoms there, such as a headache if it is in the brain. If the tumor presses on the airway, it can block that part of the lung and cause pneumonia. If it blocks a blood vessel, it can cause problems with blood flow, etc. So, it depends on where it is. ...Read moreSee 3 more doctor answers
Depends on the stage: Once diagnosed you will need to be staged to evaluate for resection. In general patients with early stage lung cancer ( i or ii ), who are healthy enough , should be treated with surgery to remove the cancer. In the more advanced stages (iii or iv) , surgery by itself is usually not curative, and other treatments like chemotherapy and radiation therapy are required. ...Read moreSee 2 more doctor answers
Bipsy and imaging: The key to diadnosis is the biopsy. This can help determine the subtype which will help guide the course of treatment. Beyond that, the imaging with ct, ct/pet, and MRI will help determine the stage of the cancer. The combination of the stage and the subtype of the cancer will help with treatment decisions as well as prognosis. ...Read moreSee 2 more doctor answers
Everything: Small cell lung cancer is almost completely different than non small cell- the only thing the same is that it is located on the lung and may give the same symptoms. They are different in molecular biology level, they look and behave differently. Small cell behaves more agressive- like systemic disease even from the first presentation; have different treatment and prognosis .D/w your oncologist. ...Read moreSee 3 more doctor answers
Entirely different: Different types of cancer. Small cell multiplies fast and is considered spread at the time of diagnosis. Because of that, it may also respond better to chemotherapy. Non-small-cell grows more slowly and if found in an early stage, may be curative by surgery. ...Read moreSee 1 more doctor answer
Not often but happen: Many of the cases of lung cancer in non-smokers, whether small cell or other - squamous cell and adenocarcinoma - are in people exposed to high levels of second-hand smoke, as well as other pollutants, including toxic industrial exposures. Asbestos exposure is a cause of another kind of lung cancer- mesothelioma - which can happen with industrial or home exposure (old insulation). ...Read more
Different cell types: lsmall cell cancer of the ung is a neuroendocrine tumor responding to chemo such as the adriamycins (doxorubicin). Non small cell cancer represents the adenocarcinomas and squamous cell cancers requiring a different groujp of drugs that usually include the platinums and the newer monoclonal antibodies. ...Read more
Friend of mine who is 48 was dx with non small cell lung cancer stage 2a what is the prognosis. Any chance of cure?
Are p63 and ttf1 used to distinguish small cell lung cancer from non small cell lung cancer? Or are they used for more specific distinctions?
Yes: Carboplatin is a very commonly used medication in this malignancy. Tolerence today is quite good, with the most important side effects being temporarily low blood counts, fatigue, numbness and nausea. A unique point about this agent is that it is dosed based on the patients kidney function, rather than the patients size like most anticancer medications. ...Read moreSee 2 more doctor answers
Deoxygenated blood enters the lungs from the right side of the heart and travels to the lungs. When you inspire, oxygen flows into the lungs, transverses the capilliares and attaches to hemoglobin down a gradient. At the same time, co2 diffuses into the capilaries and is expelled with exhalation. Oxygen rich blood then flows to the left side of the heart and into the ...Read more
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