Top
40
Doctor insights on: Non Small Cell Carcinoma

Share
1

1
Non-small cell carcinoma and small cell carcinoma. What is the difference?

Non-small cell carcinoma and small cell carcinoma. What is the difference?

Small cell. All else: Small cell cancer of the lung is a specific kind of cancer that has uniform, small cells. Non small cell cancer is the term for all other cancers that are in the lung, like adenocarcinoma, squamous cell cancer, and large cell cancer. These are grouped this way due to treatment approach. Small cell presents as widely disseminated and gets chemo., while non small cell is localized, gets surgery. ...Read more

Dr. Barry Rosen
4,351 Doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


2

2
How does non small cell carcinoma lung cancer get treated?

Multiple ways: Non-small cell cancers are a heterogenous group, with the two common types being squamous cell and adeno carcinomas. These are usually treated, depending on the stage and type, with surgery, radiation and chemotherapy. ...Read more

3

3
What is treatment involving non-small cell carcinoma?

What is treatment involving non-small cell carcinoma?

Depends upon stage: Early stage disease is usually treated by surgical resection. More advanced disease is usually treated by combination of chemotherapy and radiation therapy and stage 4 disease is usually treated with chemotherapy alone or consideration of hospice for those with significantly far advanced disease. ...Read more

4

4
Non-small cell carcinoma and small cell carcinoma. What is the difference?

Small cell. All else: Small cell cancer of the lung is a specific kind of cancer that has uniform, small cells. Non small cell cancer is the term for all other cancers that are in the lung, like adenocarcinoma, squamous cell cancer, and large cell cancer. These are grouped this way due to treatment approach. Small cell presents as widely disseminated and gets chemo., while non small cell is localized, gets surgery. ...Read more

5

5
What's non-small cell carcinoma?

What's non-small cell carcinoma?

Non Small cell ca: Is the most common type of lung cancer, another type is small cell ca (which is more aggressive). Both are challenging to diagnose at an early stage. Please consult with your oncologist for prompt diagnosis, and treatment options. Good luck. ...Read more

6

6
Non-small cell carcinoma vs small cell carcinoma?

Non-small cell carcinoma vs small cell carcinoma?

Small cell was: Distinguised because there is almost never a role for surgery, and always a role for chemotherapy. Non-small cell prior to 1980 never had chemotherapy. Both are caused by smoking sclc 100%; /nsclc 90-95%. Nsclc just in lung usually treated with surgery. Any + node gets chemo. If mediastinal nodes are positive, standard is chemo/xrt. Get more than 1 opinion before starting treatment if yo have? ...Read more

7

7
What is the definition or description of: Non small cell carcinoma?

What is the definition or description of: Non small cell carcinoma?

Lung cancer: It is broad class of lung cancers. You may consult this site for more info: http://www. Webmd. Com/lung-cancer/non-small-cell-lung-cancer#1 ...Read more

8

8
How does non small cell carcinoma lung cancer get treated?

Multiple ways: Non-small cell cancers are a heterogenous group, with the two common types being squamous cell and adeno carcinomas. These are usually treated, depending on the stage and type, with surgery, radiation and chemotherapy. ...Read more

9

9
How can non small cell carcinoma lung cancer get created?

How can non small cell carcinoma lung cancer get created?

Non small cell lung: If possible, surgical resection is the first choice. This depends on how widely spread, ir at all, the cancer is. Second choices in therapy include radiation, chemotherapy, or cyber knife. ...Read more

10

10
What is treatment involving non-small cell carcinoma?

Depends upon stage: Early stage disease is usually treated by surgical resection. More advanced disease is usually treated by combination of chemotherapy and radiation therapy and stage 4 disease is usually treated with chemotherapy alone or consideration of hospice for those with significantly far advanced disease. ...Read more

11

11
What is the definition or description of: small cell carcinoma?

What is the definition or description of: small cell carcinoma?

It is an uncommon: Type, always associated with tobacco, characteristic cellular appearance of dominant hyperchromatic nuclei, no nucleolus, scant cytoplasm. Stains with chromogranin, synaptophysin, molecular loss of rb, over production of bcl-2. It responds to chemo, but needs XRT in limited. Goes to many organs early. Need at least chemo and XRT doc to assess. ...Read more

12

12
What would the life expectancy for small cell carcinoma be?

What would the life expectancy for small cell carcinoma be?

It depends on the St: Small cell lung cancer can be localized to chest (called Limited disease) or it can be spread outside of the chest and involve other organs like liver/ Bone etc when it is called Extensive disease. So you need to tell us if your lung cancer is Limited disease or Extensive Disease? Then we can give you the relevant information about prognosis. ...Read more

13

13
How long would a person live if small cell carcinoma?

How long would a person live if small cell carcinoma?

Confined to chest: Or limited disease, there is a hance of cure. If presenting with metastasis, there is a chance of surviving well for many, but few make it beyond 2 years. Small cells can occur at other organs. You need to see a medical and a radiation oncology doctor while your work up proceeds. (head mr, bone scan, chest/abd ct + contrast thru adrenals). ...Read more

14

14
What is small cell carcinoma and why does it matter if it is small, medium, or large?

What is small cell carcinoma and why does it matter if it is small, medium, or large?

Usually this: Term refers to a smoking induced lung cancer, and teh cellular architecture is "lymphocyte like" small, filled with 'salt and pepper' nuclei, lacking nucleoli. The chromatin is fragile, crushes and streaks, but moulds like a knuckle into a ping pong ball. Other organs have generally unusual and bad cell types called small cell; the medium and large do not work here. ...Read more

15

15
Is there help for metastatic small cell carcinoma that I can live?

Is there help for metastatic small cell carcinoma that I can live?

Consult Oncologist: We can not answer but suggest you consult a oncologist as the prognosis depends on the extent of disease including metastasis and many other factors. Only they can comment on the prognosis ...Read more

16

16
How long can a person live with extensive small cell carcinoma?

How long can a person live with extensive small cell carcinoma?

Months usually: Sclc is divided into limited stage and extensive stage. The prognosis for patients with extensive stage disease is grim, with most passing away within a year or so. Patients with limited stage disease are potentially curable, but the odds are also not good. Only about 15-20% of these patients will be alive 5 years after diagnosis. ...Read more

17

17
I have one small spot on one lung of small cell carcinoma. What's the survival rate?

Fairly good: This type of tumor is sensitive to chemotherapy. The question is whether this is primary or metastatic from a non pulmonary origin. In either case if this is the only lesion, a thorascopic resection of the nodule can give total control. This can then be followed by adjuvant chemo. ...Read more

18

18
What to do if one small spot on one lung of small cell carcinoma what's the survival rate?

What to do if one small spot on one lung of small cell carcinoma what's the survival rate?

Resection: If it is an early stage SCC you need to see a cardio thoracic surgeon and plan for a resection.
Of course you have to complete a PET CT for staging and Pulmonary Function tests to assess if you are a surgical candidate. ...Read more

19

19
What is small cell carcinoma lung cancer with liver cancer stage 4?

What is small cell carcinoma lung cancer with liver cancer stage 4?

Bad situation: Small cell is a very bad cancer.
Stage four is very advanced.
Very poor prognosis at best-- usually months only. ...Read more

20

20
What is the latest treatment for small cell carcinoma of the lung with bone metastases?

Clinical trial: Clinical trial or standard chemotherapy.
Bone mets can be treated with bisphosphonate (zometa) or Denosumab (xgeva).
Mri of the brain should evaluate for brain mets.
Trials: http://clinicaltrials. Gov/ct2/results? Term=small+cell+lung+cancer&recr=open&no_unk=y
standard of care chemotherapy is a 2 drug combination with a "platinum". ...Read more

21

21
What can I expect the outcome to be with stage 4 non small cell cancer and pneumonia? Prognosis?

What can I expect the outcome to be with stage 4 non small cell cancer and pneumonia? Prognosis?

I'm very sorry: I'm very sorry because likely either you or an individual you care about is affected by this cancer. No physician has a crystal ball, but tumor type, size, and patient's health condition all play a role. Some non-small cell lung cancers may have genetic mutations (EGFR, Alk, Ros) that may be sensitive to "targeted therapies" which may prolong, but are unlikely to cure the disease. Good luck! ...Read more

22

22
What is non-small cell lung cancer?

What is non-small cell lung cancer?

See below: Non-small cell lung cancer is a type of lung cancer that grows more slowly and can be operated on if diagnosed at an early stage. It generally has a better prognosis than small-cell lung cancer, but that is depending on the stage and comorbidities. ...Read more

23

23
In december 2005 I had non-small cell lung cancer. What are the chances of relapse?

In december 2005 I had non-small cell lung cancer. What are the chances of relapse?

Not common: Since you have been disease free for nearly 7 years it would be unusual for a recurrence. There might be risk for a second new lung cancer depending on the original type and smoking history. ...Read more

24

24
Can non small cell cancer of the lung spread?

Yes: Unfortunately non small cell lung cancer can spread; frequent sites of spread include the space between the lung and chest wall (pleural space), liver and adrenal glands. When the disease spreads to distant organs/locations this is called metastasis. ...Read more

25

25
What are the tests for non-small cell lung cancer?

What are the tests for non-small cell lung cancer?

Nsclc: First of all, a biopsy will need to be done to the lung mass/nodule not only to establish diagnosis but also to find the histology and genetic profile of the cancer. Then, complete staging work-up with pet/ ct scan need to be done to stage the cancer. The treatment will depend on the histology/molecular-genetic mutation status, stage, as well as overall condition and preference of a patient. ...Read more

26

26
What's the prognosis for non small cell lung cancer?

What's the prognosis for non small cell lung cancer?

5yr suvival bystage: Ia = 49%
ib = 45%
iia = 30%
iib = 31%
iiia = 14%
iiib = 5%
iv = 1%
http://www. Cancer. Org/cancer/lungcancer-non-smallcell/detailedguide/non-small-cell-lung-cancer-survival-rates. ...Read more

27

27
Could you explain what is non small cell lung cancer?

Could you explain what is non small cell lung cancer?

One type of lung: Cancer. It is not easy to explain. There are multiple subtypes within in this type. These are due to smoking and tend to spread locally as compared to early spread through blood for small cell cancer. See this site for more info.

http://www. Cancer. Gov/cancertopics/pdq/treatment/non-small-cell-lung/patient/page1. ...Read more

28

28
Which lung cancer is worse, small cell or non small cell?

Which lung cancer is worse, small cell or non small cell?

Apples vs oranges: With small cell, a good response to chemotherapy -- for a while -- followed by death is the predictable outcome, and it's fast when it comes. For the others -- less predictable, and slower. Best wishes. ...Read more

29

29
What is the survival percentage non small cell lung cancer?

What is the survival percentage non small cell lung cancer?

The stage and others: Will depend on the stage and other prognostic factors. In general, the 5 year overall survival for stage 1 is 60-80%., stage 2 is 40-50%; stage 3 is 10-23%, and stage 4 is less than 10%. These however are the statistics obtained when using regular cytotoxic chemotherapy. With more personalized and more targetted therapy-we are hoping the number will improve. ...Read more

30

30
What is surgery like for non small cell lung cancer?

What is surgery like for non small cell lung cancer?

Often cures: Surgery is the standard of care for stage I and ii lung cancer in the physically fit patient, and should be considered as an option in many patients with stage iiia. Often can be done minimally invasively thorascopically or with a robot. Recovery varies with the level of invasiveness. Lung surgery has best outcomes by a board certified thoracic surgeon. ...Read more

31

31
What are the surgical options for non-small cell lung cancer?

What are the surgical options for non-small cell lung cancer?

Robot or VATS: Optimal lung cancer surgery, in appropriate candidates, is anatomic lobectomy (part of lung) or pneumonectomy (whole lung). Complete lymph node sample or dissection is integral part of case. Traditional centers use thoracotomy as primary approach. Modern minimally invasive approaches include vats and robotic techniques. Optimal lung cancer treatment is by comprehensive multidisciplinary approach. ...Read more

32

32
If you get non-small cell lung cancer, how do you feel?

If you get non-small cell lung cancer, how do you feel?

It depends;: Unfortunately lung cancer is usually diagnosed in more advanced stages because it can be silent. Depending on the region it involves, symptoms could varry from cough, weight loss, shortness of breath, coughing up blood, affecting voice quality. If cancer is found incidentally in early stages (patient not symptomatic and cancer found incidentally), the cure rate can be excellent. ...Read more

33

33
What is the best way to treat non small cell lung cancer?

What is the best way to treat non small cell lung cancer?

Stage is key: The stage or amount of cancer present helps determine if surgery, or other treatments are the best first step. The early stages are best treated with surgery. Sometimes chemotherapy and radiation are used.
There is no single way to say what is the best treatment. ...Read more

34

34
Is non-small cell lung cancer often a non-smokers cancer?

Yes: There are several types of non-small cell lung cancer. Typically squamous cell is associated with smoking. Adenocarcinoma isn't usually related to smoking. ...Read more

35

35
What are the symptoms associated of non-small cell lung cancer?

What are the symptoms associated of non-small cell lung cancer?

Depends: That depends on where the tumor is: if it is spread to a vital organ, it will causes symptoms there, such as a headache if it is in the brain. If the tumor presses on the airway, it can block that part of the lung and cause pneumonia. If it blocks a blood vessel, it can cause problems with blood flow, etc. So, it depends on where it is. ...Read more

36

36
If I develop non-small cell lung cancer, how will it be treated?

Depends on the stage: Once diagnosed you will need to be staged to evaluate for resection. In general patients with early stage lung cancer (i or ii), who are healthy enough, should be treated with surgery to remove the cancer. In the more advanced stages (iii or iv), surgery by itself is usually not curative, and other treatments like chemotherapy and radiation therapy are required. ...Read more

37

37
What is the definition or description of: Non small cell lung cancer?

What is the definition or description of: Non small cell lung cancer?

Non Small Cell Lung: Cancer= the most common category of lung cancer, a descriptive term encompassing a group of lung cancers that behave similarly, literally any epithelial lung cancer that is not histologically a small cell cancer ...Read more

38

38
What should I know about nsclc (non small cell lung cancer)?

What should I know about nsclc (non small cell lung cancer)?

Smoking: It is frequently caused by smoking. There is too much to discuss in 400 words! Try this:

http://www.Cancer.Gov/cancertopics/pdq/treatment/non-small-cell-lung/patient/page1. ...Read more

39

39
Can people survive non small cell lung cancer?

Can people survive non small cell lung cancer?

Yes, depends stage: Stage 1 nsclc; surgical resection, appr70%5yrsurv
stage2nsclc;surgery apprx. 30-35% 5 yr survival. ...Read more

40

40
Can you tell me about non-small cell lung cancer?

Can you tell me about non-small cell lung cancer?

Not enough space: Let's see: most common category of lung cancer, often but not always tobacco related, treated with surgery if possible but radiation and chemo are often used as well. I suggest you visit the national cancer institute website. It's has good info regarding all kinds of cancers. ...Read more