Doctor insights on:
Non Parathyroid Hypercalcemia
High parathyroid related peptide and hypercalcemia with elevated ACE in 12 yr old. Clear pet scan, CT scan and bone marrow. On prednisone to control.
Is weight hard to lose with hypercalcemia and hyperparathyroidism? Also is extreme fatigue related to this as well?
Expectations: You can expect to live a healthy and happy life once your diagnosis is thoroughly diagnosed and properly treated. ...Read more
Anybody: There are a few hereditary causes of parathyroid disease which can increase your risk above the general population but generally speaking, parathyroid disease can occur in anyone and at any age, although the average is around 60 years of age. ...Read more
Parathyroid Glands: The parathyroid glands are 4 small groups of tissue that sit behind the thyroid gland. They make parathyroid hormone or PTH which is involved in calcium metabolism. Too much PTH causes the calcium level in the blood to go up. An overactive parathyroid gland is often diagnosed when a routine blood test shows a high calcium level. ...Read more
Regulates calcium.: They make parathyroid hormone (PTH), which regulates the body's calcium and phosphate levels. These levels are important for normal nerve and muscle function. PTH tells bone to break down and release calcium into the blood. In the gut, it converts vitamin D to its active form which absorbs more calcium. It also tells kidneys to allow less calcium and phosphate to leave the body through urine. ...Read more
Regulate calcium: The parathyroid glands secrete a hormone that keeps the level of calcium in the blood from falling. It does this by pulling calcium from the bone and by preventing loss of calcium through the kidney. It is also necessary to convert vitamin d into its active form, which in turn increases calcium absorption in the gut. ...Read more
Yes and no: Parathyroid disorder can occur in anyone but it could also be hereditary (that is if a family member has hyperparathyrodiism, you are at higher risk of developing the disease). There is also a condition called men (multiple endocrine neoplasm) that can increase your risk of parathyroid disease if someone in your family has it. ...Read more
Many: If it's hyperparathyroidism, the best treatment is surgery. Medications and possibly alcohol injection can be used but these are inferior to surgery and only considered when surgery is refused or contraindicated. If it's hypoparathyroidism, the treatment is calcium and vitamin d (both inactive and active) replacement. ...Read more
See below: Depends on how it is being done, minimal incision or full neck incision. Depends on if it is for only one parathyroid gland, or if all four glands are being evaluated at surgery. Low risk of nerve damage to the vocal cord, low risk of infection, low risk of bleeding and swelling after surgery. Low risk of not being able to locate the offending gland at surgery requiring another surgery later. ...Read more
Many symptoms: Parathyroid hormone is responsible for regulating calcium level in blood. If high, it will raise calcium level in your blood causing osteoporosis, kidney stones, kidney problems, bone pain, constipation, abdominal pain, psychological problems...If low, it can cause low calcium in the blood resulting in numbness/tingling, muscle cramps, fatigue, irritability, seizures, uncontrolled movements... ...Read more
There are several...: Symptoms are related to an elevated level of parathyroid hormone, which causes a high blood calcium level. Minimal symptoms are present until the calcium level is so high as to cause kidney stones, GI "moans" (constipation, nausea, belly pain), psychic "groans" (confusion, dementia, depression, etc.), and pain in the bones, including diffuse bone pain and fractures. ...Read more
1. Ultrasound because it's cheap and can be done by most high volume practitioners in their office.
2. 4D CT. This is new but far superior to the former number 2.
3. SPECT CT Tc 99 sestamibi or other sestamibi based scan.
4. If you go to 4 or beyond, your a special case and make sure you have a really experienced surgeon. ...Read more
Odd question: These two conditions are not related in any way that I can see. PCOS is a complex syndrome with irregular menses, abdomen obesity, insulin resistance, hirsutism, excess androgens. Hypercalcemia is often asymptomatic, but there can be kidney stones, osteopenia, bone pain. See your doctor. ...Read more
Many: If the adenoma produces extra parathyroid hormone, you can have high calcium concentration in your blood which can cause many symptoms and conseuquences including: constipation, abdominal pain, fatigue, musle weakness/twiches, renal insufficiency, excessive urination and dehydration, kidney stone production, osteoporosis, memory loss, depression...It needs to be evaluated and taken seriously. ...Read more
Neck: The parathyroid glands are diffierent than the thyroid gland (they share part of the name but their functions are very diffierent). There are 4 parathyroid glands. They are usually located on the back of the thyroid gland but they can also be located around the jaw and neck as well. ...Read more
Parathyroid problems: Hi. Too complex for small space. Primary hyperpara (PHPT) is a disease of parathyroids where too much PTH is secreted, which causes high blood calcium, with symptoms/signs of kidney stones, bone fractures, malaise, depression, high blood pressure, and others. Hypoparathy is a disease of parathyroids where they can't secrete enough PTH, with symptoms of numbness, tingling, and muscle twitching. ...Read more
Three more remaining: There are four parathyroid glands situated in the neck, behind the thyroid gland -- two on left and two on right, usually a few centimeters apart. These glands make parathyroid hormone (PTH) that control calcium and bone metabolism. Usually only 0.5 to 1 parathyroid is sufficient to make enough pth. If 3 to 3.5 glands are damaged or removed, the body can still maintain PTH and calcium control. ...Read more
Low blood calcium: If one parathyroid gland is removed complications are unusual. If all 4 glands are removed blood calcium levels develop immediately and if untreated lead to tingling and cramps and occasionally a seizure. A nerve supplying a vocal cord could also be damaged and cause hoarseness. ...Read more