Doctor insights on:
Non Megaloblastic Anemia
Decreased Hemoglobin: Red blood cells (rbcs) are essentially little bags carrying lots of hemoglobin (hb). Iron is an important constituent of the hb molecule. Low iron = low hemoglobin = less packing into rbc. Since the RBC is now filled less, a microcytic anemia results. ...Read moreSee 1 more doctor answer
Pernicious = Vit B12: Megaloblastic anemia refers to any condition which causes large red blood cells (folate (folic acid) deficiency, vitamin B12 deficiency, etc.) pernicious anemia can be thought of as a *type* of megaloblastic anemia which is caused by vitamin B12 deficiency secondary to malabsorption. ...Read moreSee 1 more doctor answer
Anemia: Megaloblastic anemia is anemia related most commonly to vitamin B12 and Folic Acid deficiency. These problems are easily treated with replacement of the deficient vitamin. There are other much rarer causes of megaloblastic anemia, and other illnesses that may look similar to megaloblastic anemia. ...Read more
Megaloblastic anemia: Megaloblastic anemia (or megaloblastic anaemia) is an anemia (of macrocytic classification) that results from inhibition of DNA synthesis during red blood cell production.The defect in red cell DNA synthesis is most often due to hypovitaminosis, specifically a deficiency of vitamin B12 and/or folic acid. ...Read moreSee 3 more doctor answers
It just does :): Hello- your body needs Folic Acid to make red blood cells properly. If you do not have enough it compromises the process. The body will not be able to produce red blood cells as well (anemia) and they will be bigger than normal red blood cells (megaloblastic = big). Thankfully some Folic Acid replacement should fix the problem quite easily. ...Read moreSee 2 more doctor answers
Not clear: No clear evidence for the causal-effect relationship between the two. PA is an autoimmue-mediated destruction of parietal cells in stomach, resuling in impairmnent of B12 absorption. Certainly it is possible that pernicious anemia may co-exist or exacerbate duodenitis via immune process or loss of balance in duodenal fluid, or anemia. But the causal-effect relationship is not well established. ...Read moreSee 2 more doctor answers
Malaria doesnt cause: Sickle cell anemia is a hereditary disease caused by a mutation in the dna coding for hemoglobin. Scientists have long known that sickle cell anemia protects carriers from malaria infections, which could be advantageous in certain parts of the world. Malaria does not cause sickle cell anemia. ...Read moreSee 1 more doctor answer
Can MCV be normal if peripheral smear for blood show microcytic hypochromic anemia without B12 or folate (folic acid) deficiency?
Depends on cause: Chronic pancytopenia means low white & red cells and low platelets. Reversible causes such as nutritional deficinecies, immune disorders, drug-related can be treated effectively. However, patientsw with inherited conditions or bone marrow disorders need a detailed work-up and treatments may not be effective. ...Read moreSee 1 more doctor answer
Anemia: The only thing similar is that both have anemia ( decrease level of hemoglobin ). That is all. Sickle cell anemia and aplastic anemia are completely different disorders. Each has different pathogenesis, different clinical manifestation/symptoms, etiologies, treatments etc. ...Read moreSee 1 more doctor answer
Hemolytic anemia: Anemia can be due to many factors and to even begin to know, clues are found on the size(normo, macro, micro) and coloration (hypo(pale color), normochromic(normal red color). When red cells lack a normal center, as in spherical forms, " hyperchromic" is used loosely, though the correct term may be spherocytes. Hemolytic anemia, with many causes, lead to normochromic "hyperchromic"anemia. ...Read more
Not commonly: Most cases of this condition reflect deficiencies of key vitamins (b12, folic acid) and occur due to dietary deficiencies, pregnancy, pernicious anemia, medications. Rare inherited forms can occur in which the carrier proteins for B12 may be low for example. ...Read moreSee 1 more doctor answer
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