Doctor insights on:
Nodules On Colon Cancer
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
On a CT report radiologist states 'Nodules" in a metastic colon cancer patient. Why would He not put any measurements?
You are right,: There should be some measurements, except perhaps if the nodules have been described on prior CT reports, are a known finding, and are unchanged. ...Read more
If a person with colon cancer has a liver met, 1 node and 1. 0.5 mm nodule In lobe, what is approx prognosis? Primary removed last yr
Not good: Once a cancer had metastasized, it becomes inoperable and the only way to slow it down is with either radiation and or chemotherapy when these treatments work. Ultimately the treatment itself produces immunosuppression and makes the patient susceptible to infection which is often the actual cause of death. All these variables impact the length of survival. ...Read more
Yes: Depending on the Dukes classification as to extent of tumor into bowel wall and number of lymph nodes involved the chances of a lung lesion being metastasis is a possibility. A PET/CAT will help identify the lesion as met or not. If neg. Careful follow up and possible biopsy might be necessary. ...Read more
Is nano knife a good option to remove mets from Colon cancer? Mets are- 1 in liver, 1 node, 1 sub pleural nodule. All small and chemo Not Worked.
Only certain lesions: Mets from colon cancer when smaller than 5 cm and exta hepatic in orign are good targets for nano knofe therapy. In the liver when there is no response to chemo one has many options including chemoembolization, isotope infusion or infusion with rasiolabelled microspheres. When chemo fails one can also add the newer immunotherapeutic agents. ...Read more
I have a 4x3mm sub plural nodule lower right lobe w/family history of lung and colon cancer. Should I get further testing?
What were you told?: These little nodules are extremely common especially in areas where histoplasmosis is endemic, like my home in Kansas. If you look hard enough, probably a majority of folks have them. Unless your radiologist recommends an attempt at a biopsy, I'd forget about it or as maximum monitor it by imaging. There's really no test except biospy; and it's too small to hit easily with a needle. ...Read more
Complicated: Measurement of lesions at CT is not a trivial task. Measurement in the axial plane in two dimensions may not reflect the volume of the lesion. The measurement is affected by slice thickness and window and level settings. RECIST 1.1 is a standard for tumor measurement, but it seems outdated with modern CT. Development of new lung lesions in high risk colon ca is bad, size willnot affect therapy. ...Read more
Colon cancer pt with 1 met in liver, 1 node, 1 sub pleural nodule. Chemo resistence. Tried Xeloda (capecitabine) and irinotecan both. Can anyting be done?
Try HT Concierge: Marilyn, given your situation, you need more advice that can be given in short answers like this. I would recommend a second opinion in England, In whatever regional center is best. In addition, consider health top concierge. Several excellent oncologists are available by searching. Hang in there! ...Read more
Colon cancer, primary removed. Now 1 liver met, 1 node n 1 aortocaval nodule. Chemo irinotecan n Xeloda (capecitabine) has not worked. Wats survival few years?
Can ablation be beneficial for metastic colon cancer with the following : 1 liver met, 1 node, 1 sub plueral nodule? Chemo not worked
STOP!: You need to stop wasting your time and my time. I have answered this question multiple times and you still keep asking about it again and again! . What are you looking for???? ...Read more
If chemotherapy fails, and there is a tiny new lung nodule, 1 liver met and 1 node can anything b done in colon cancer pt aged 65?
Colon cancer pt. Old ct- nodule on left adrenal gland. (was not met). New ct- new adrenal nodule. Are these the same or diffetent ones, ?
Must compare CT's: The best way to tell if these are the same nodule or if this is a new nodule would be to have the radiologist or your oncologist compare the CT's side-by-side. It may be obvious that they are or are not the same nodule. If it is not obvious, then further testing may be necessary, perhaps even a biopsy of the nodule if it is worrisome. Good luck. ...Read more
What is prognosis like for colon cancer pt with 1 liver met, 1 node and 0.5 lung nodule? Primary was resected last year. Cea 10. Bloodwork normal?
Prognosis: Prognosis is determined at time of diagnosis/treatment. Seems cancer is/was stage 4, which has a shorter prognosis than stage 1. If stage 4 is NEW, newly discovered liver metastasis, then prognosis will be negatively impacted compared to a year ago. Regardless of prognosis, talk with your docs. Take friend/family with you to appointments to help with understanding. Treatments exist. Be well. ...Read more
Afraid so: Given the circumstances you described the lung nodule would be presumed to be a met unless proven otherwise. Does the person have liver mets? If yes, then the lung nodule is more likely to be met. ...Read more
If a lung nodule remains unchanged on the three month CT scan, it's less likely a met right in a colon cancer or?
Less likely but!: Pulmonary nodules that are stable by CT fit 2 yrs are benign. 3 months is not long enough to be certain. More follow up needed. ...Read more
If chemotherapy treatment fails for metastic colon cancer pt, what else can be done for a liver met, 1 node and a tiny lung nodule?
Remove lung lesion: At age 34 attempt at cure should be made. If liver met small and primary already out, liver met to be resected or microwave ablated. Usually chemo is only of temporary value and if all fails, the FDA protocol for monoclonal antibody Neo102 is available for treatment of metastatic colon cancer having failed chemo. The small node and lung lesion can be removed by laparoscopy/thoracoscopy. ...Read more
Can anything b done for a liver met, 1 lung nodule and a lypmph node if chemo fails? Does this mean no treatment for colon cancer pt? Primary removed
Metastatic colon CA: Typically, metastatic cancer (cancer that has spread to organs/areas beyond where it started) is considered incurable. There are some exceptions; if colon cancer has a single metastasis to the liver OR a lung, then chemotherapy & surgical removal of the met might be successful (perhaps 50%).For more than one organ, chances are less, & treatment frequently shifts towards comfort if chances poor/none. ...Read more
Cancer of the colon: Cancer that forms in the tissues of the colon (the longest part of the large intestine). Most colon cancers are adenocarcinomas (cancers that begin in cells that make and release mucus and other fluids). There are estimated 103, 170 (colon); 40, 290 (rectal) new cases and 51, 690 (colon and rectal combined) deaths from colon cancer in us in 2012. Screening with colonoscopy started at age of 50. ...Read more
Cancers: Cancers are abnormal, rapidly growing cells that do not know when to stop growing. These abnormal cells can damage local tissues, can attach to nearby organs or structures, can spread to lymph nodes, or can spread to other organs through the blood stream. Their growth damages what they are attached to, and often cancers encourage new blood flow to themselves. Cancer can grow in the colon. ...Read more
Not always: Colon cancer tends to not have any signs or symptoms when it is early (when it is easiest to treat). That is why screening colonoscopies are so important, to remove any polyps that may become cancer, and to directly look for cancers. Colon cancer can cause bleeding from the rectum, tiredness from anemia, stool changes, or abdominal pain. Other things can cause this too. Best to be seen if? S. ...Read more
Early detection!: The best thing that improves the chances of curing colon cancer is early detection. So preventive health care and screening are key. All adults should have a colonoscopy at age 50 to look for cancers or early cancers, usually as polyps. If you have a strong family history or certain conditions it is recommended you get earlier screening. Once detected, colon ca usually is cured by surgery, or drugs. ...Read more
Very complicated: Monoclonal theory says that just like we are a living thing, we are born, we have jobs to do and then we die, each cell has a similar cycle of birth, life, and death. Cancer occurs when a cell develops so many mutations that it does not follow that cycle and does not die but can still divide itself and hides from our immune system which is there to detect abnormal cells and destroy them. ...Read more
Genes: Most colon cancers are not inherited. However, there is a subset which is associated with inherited genetic abnormalities such as hereditary polyposis a this hereditary non polyposis gene (hnpp). There are also syndromes that make you susceptible to a variety of different cancers including colon cancer such as lynch syndrome. ...Read more
None really...: In the majority of patients (over 80%), colon cancer is silent. Symptoms and signs of altered stool pattern or appearance, weight loss, blood in the stool are often late manifestations of advanced disease. Unfortunately, these signs are nonspecific, and can present with many other GI issues--so don't freak out if you are experiencing them. Just get checked. ...Read more
Any symptoms?: It is very rare that you would at your age, but our med school had a scholarship named for a 26yr old med student who passed from colon cancer. If you are having symptoms, such as bleeding with bowel movements, unexplained pain or pressure, weight loss, or have a family history, or have other issues like inflammatory bowel disease, see your doc for some easy tests and go from there. Best of luck! ...Read more
Colon cancer: Colon Cancer may have no apparent signs until late in its course, such as bleeding in the stool, early satiety, bowel pain or discomfort, a change in bowels (diarrhea/constipation/consistency of stool). That is why it is important to get your routine screening tests at age 50 or younger if with a family history, and see your dr for regularly scheduled visits. Also, Never SMOKE or QUIT if you do! ...Read more
Signs or symptoms can include any of the following, change in your bowel habits, including diarrhea or constipation, change in the consistency of your stool, rectal bleeding or blood in your stool, persistent abdominal pain
a feeling that your bowel doesn't empty completely, weakness or fatigue from anemia. Also unintentional significant weight loss can be a sign. See your md if these occur. ...Read more
Combination: Environmental and genetic factors can increase the likelihood of developing colorectal cancer. 70% of cases are sporadic cases, only about 10% is a true inherited cancer and approximately 25% is familial type. Some risk factors include- inflammatory bowel disease, dietary habit (processed red meat), dm, alcohol, growth hormone, obesity, cigarette, immunosupressant, age, etc. ...Read more